Towards an analytic solution for pulsed CEST
Chemical exchange saturation transfer (CEST) is an imaging method based on magnetization exchange between solutes and water. This exchange generates changes in the measured signal after off‐resonance radiofrequency irradiation. Although the analytic solution for CEST with continuous wave (CW) irradiation has been determined, most studies are performed using pulsed irradiation. In this work, we derive an analytic solution for the CEST signal after pulsed irradiation that includes both short‐time rotation effects and long‐time saturation effects in a two‐pool system corresponding to water and a low‐concentration ex...
Source: NMR in Biomedicine - February 20, 2018 Category: Radiology Authors: Daniel F. Gochberg, Mark D. Does, Zhongliang Zu, Christopher L. Lankford Tags: RESEARCH ARTICLE Source Type: research
Towards an analytic solution for pulsed CEST
NMR in Biomedicine, EarlyView. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 20, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine, Ahead of Print. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 20, 2018 Category: Radiology Source Type: research
Analysis of 13C and 14C labeling in pyruvate and lactate in tumor and blood of lymphoma ‐bearing mice injected with 13C‐ and 14C‐labeled pyruvate
This study shows that measurements of hyperpolarized 13C label exchange between pyruvate and lactate in a murine tumor model can provide an estimate of the true isotope flux if the concentration of labeled pyruvate that reaches the tumor can be determined.
Metabolic imaging with hyperpolarized [1‐13C]pyruvate has shown great promise in preclinical and clinical studies. This study shows, in a murine tumor model, that only a small fraction of the injected hyperpolarized [1‐13C]pyruvate reaches the tumor and that measurements of hyperpolarized 13C label exchange between pyruvate and lactate can provide a true estimate of...
Source: NMR in Biomedicine - February 19, 2018 Category: Radiology Authors: E.M. Serrao, M.I. Kettunen, T.B. Rodrigues, D.Y. Lewis, F.A. Gallagher, D.E. Hu, K.M. Brindle Tags: RESEARCH ARTICLE Source Type: research
Analysis of 13C and 14C labeling in pyruvate and lactate in tumor and blood of lymphoma ‐bearing mice injected with 13C‐ and 14C‐labeled pyruvate
NMR in Biomedicine, EarlyView. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 19, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine, Ahead of Print. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 19, 2018 Category: Radiology Source Type: research
Maximizing sensitivity for fast GABA edited spectroscopy in the visual cortex at 7 T
The combination of functional MRI (fMRI) and MRS is a promising approach to relate BOLD imaging to neuronal metabolism, especially at high field strength. However, typical scan times for GABA edited spectroscopy are of the order of 6‐30 min, which is long compared with functional changes observed with fMRI.
The aim of this study is to reduce scan time and increase GABA sensitivity for edited spectroscopy in the human visual cortex, by enlarging the volume of activated tissue in the primary visual cortex. A dedicated setup at 7 T for combined fMRI and GABA MRS is developed. This setup consists of a half volume multi‐t...
Source: NMR in Biomedicine - February 14, 2018 Category: Radiology Authors: Arjan D. Hendriks, Alessio Fracasso, Catalina S. Arteaga de Castro, Mark W.J.M. Gosselink, Peter R. Luijten, Natalia Petridou, Dennis W.J. Klomp Tags: RESEARCH ARTICLE Source Type: research
Maximizing sensitivity for fast GABA edited spectroscopy in the visual cortex at 7 T
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 14, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 14, 2018 Category: Radiology Source Type: research
Issue Information
No abstract is available for this article. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 14, 2018 Category: Radiology Tags: ISSUE INFORMATION Source Type: research
Cover Image, Volume 31, Issue 3
The cover image, by Katharina Paul et al., is based on the Research Article Multiband diffusion‐weighted MRI of the eye and orbit free of geometric distortions using a RARE‐EPI hybrid, DOI: 10.1002/nbm.3872. The authors would like to thank Oliver Stachs, University of Rostock for his support of the publication of this cover. Photo Credit: Celal Özerdem, The Berlin Ultrahigh Field Facility (B.U.F.F.) at the Max Delbrück Center. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 14, 2018 Category: Radiology Authors: Katharina Paul, Till Huelnhagen, Eva Oberacker, Daniel Wenz, Andr é Kuehne, Helmar Waiczies, Sebastian Schmitter, Oliver Stachs, Thoralf Niendorf Tags: COVER IMAGE Source Type: research
Comparison of reproducibility of single voxel spectroscopy and whole ‐brain magnetic resonance spectroscopy imaging at 3T
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 13, 2018 Category: Radiology Source Type: research
Corrigendum
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 13, 2018 Category: Radiology Source Type: research
Cortical structural involvement and cognitive dysfunction in early Parkinson's disease
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 13, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 13, 2018 Category: Radiology Source Type: research
