Cortical structural involvement and cognitive dysfunction in early Parkinson's disease
Magnetic resonance imaging (MRI) studies in early Parkinson's disease (PD) have shown promise in the detection of disease‐related brain changes in the white and deep grey matter. We set out to establish whether intrinsic cortical involvement in early PD can be detected with quantitative MRI. We collected a rich, multi‐modal dataset, including diffusion MRI, T1 relaxometry and cortical morphometry, in 20 patients with early PD (disease duration, 1.9 ± 0.97 years, Hoehn & Yahr 1–2) and in 19 matched controls. The cortex was reconstructed using FreeSurfer. Data analysis employed linked independent component analys...
Source: NMR in Biomedicine - February 13, 2018 Category: Radiology Authors: J.C. Klein, M. Rolinski, L. Griffanti, K. Szewczyk ‐Krolikowski, F. Baig, C. Ruffmann, A.R. Groves, R.A.L. Menke, M.T. Hu, C. Mackay Tags: RESEARCH ARTICLE Source Type: research
Corrigendum
(Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 13, 2018 Category: Radiology Tags: CORRIGENDUM Source Type: research
Spin ‐lock imaging of early tissue pH changes in ischemic rat brain
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 9, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 9, 2018 Category: Radiology Source Type: research
Quantitative MRI in murine radiation ‐induced rectocolitis: comparison with histopathological inflammation score
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 6, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 6, 2018 Category: Radiology Source Type: research
Comparison of metabolic adaptations between endurance ‐ and sprint‐trained athletes after an exhaustive exercise in two different calf muscles using a multi‐slice 31P‐MR spectroscopic sequence
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 2, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 2, 2018 Category: Radiology Source Type: research
Multi ‐compartmental diffusion characterization of the human cervical spinal cord in vivo using the spherical mean technique
NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 1, 2018 Category: Radiology Source Type: research
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NMR in Biomedicine,Volume 31, Issue 4, April 2018. (Source: NMR in Biomedicine)
Source: NMR in Biomedicine - February 1, 2018 Category: Radiology Source Type: research
Comparison of reproducibility of single voxel spectroscopy and whole ‐brain magnetic resonance spectroscopy imaging at 3T
To date, single voxel spectroscopy (SVS) is the most commonly used MRS technique. SVS is relatively easy to use and provides automated and immediate access to the resulting spectra. However, it is also limited in spatial coverage. A new and very promising MRS technique allows for whole‐brain MR spectroscopic imaging (WB‐MRSI) with much improved spatial resolution. Establishing the reproducibility of data obtained using SVS and WB‐MRSI is an important first step for using these techniques to evaluate longitudinal changes in metabolite concentration. The purpose of this study was to assess and directly compare the repr...
Source: NMR in Biomedicine - February 1, 2018 Category: Radiology Authors: Yue Zhang, Edward Taub, Nouha Salibi, Gitendra Uswatte, Andrew A. Maudsley, Sulaiman Sheriff, Brent Womble, Victor W. Mark, David C. Knight Tags: RESEARCH ARTICLE Source Type: research
Spin ‐lock imaging of early tissue pH changes in ischemic rat brain
We have previously reported that the dispersion of spin‐lattice relaxation rates in the rotating frame (R1ρ) of tissue water protons at high field can be dominated by chemical exchange contributions. Ischemia in brain causes changes in tissue pH, which in turn may affect proton exchange rates. Amide proton transfer (APT, a form of chemical exchange saturation transfer) has been shown to be sensitive to chemical exchange rates and able to detect pH changes non‐invasively following ischemic stroke. However, the specificity of APT to pH changes is decreased because of the influence of several other factors that affect ma...
Source: NMR in Biomedicine - February 1, 2018 Category: Radiology Authors: Zhongliang Zu, Aqeela Afzal, Hua Li, Jingping Xie, John C. Gore Tags: RESEARCH ARTICLE Source Type: research
Quantitative MRI in murine radiation ‐induced rectocolitis: comparison with histopathological inflammation score
Murine radiation‐induced rectocolitis is considered to be a relevant animal model of gastrointestinal inflammation. The purpose of our study was to compare quantitative MRI and histopathological features in this gastrointestinal inflammation model.
Radiation rectocolitis was induced by localized single‐dose radiation (27 Gy) in Sprague‐Dawley rats. T2‐weighted, T1‐weighted and diffusion‐weighted MRI was performed at 7 T in 16 rats between 2 and 4 weeks after irradiation and in 10 control rats. Rats were sacrificed and the histopathological inflammation score of the colorectal samples was assessed.
The irradi...
Source: NMR in Biomedicine - February 1, 2018 Category: Radiology Authors: Magaly Zappa, Sabrina Doblas, Dominique Cazals ‐Hatem, Fabien Milliat, Jérémy Lavigne, Fanny Daniel, Abelhak Jallane, Philippe Garteiser, Valérie Vilgrain, Eric Ogier‐Denis, Bernard E. Van Beers Tags: RESEARCH ARTICLE Source Type: research
