Neuropathology and Applied Neurobiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Meningeal SWI/SNF related, matrix ‐associated, actin‐dependent regulator of chromatin, subfamily B member 1 (SMARCB1)‐deficient tumours: an emerging group of meningeal tumours
ConclusionsThe phenotype and genotype of these two cases did not fit diagnostically with entities already known to be SMARCB1‐deficient tumours. As both tumours shared common features, they are regarded as belonging to an emerging group of primary meningeal SMARCB1‐deficient tumours, not described to date. To facilitate the identification and characterization of these tumours, we recommend SMARCB1 immunohistochemistry for primary meningeal tumours which are difficult to classify, especially if immunopositive for EMA and CD34. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - December 27, 2016 Category: Neurology Authors: B. Dadone, D. Fontaine, L. Mondot, G. Cristofari, A. Jouvet, C. Godfraind, P. Varlet, D. Ranch ère‐Vince, J.‐M. Coindre, L. Gastaud, C. Baudoin, A.‐C. Peyron, A. Thyss, M. Coutts, J.‐F. Michiels, F. Pedeutour, F. Burel‐Vandenbos, Tags: Original Article Source Type: research

Sudan black: a fast, easy, and non ‐toxic method to assess myelin repair in demyelinating diseases
ConclusionOur adapted sudan black staining can be used to rapidly and non‐toxically screen for remyelinating therapies in demyelinating diseases.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - December 22, 2016 Category: Neurology Authors: Benjamin. V. Ineichen, Oliver Weinmann, Nicolas Good, Patricia Plattner, Carla Wicki, Elisabeth J. Rushing, Michael Linnebank, Martin E. Schwab Tags: Original Article Source Type: research

Distinctive genomic signature of neural and intestinal organoids from familial Parkinson's disease patient ‐derived induced pluripotent stem cells
ConclusionWe provide the first evidence that LK2GS also causes significant changes in gene expression in the intestinal cells. These hNES and hIO models from the same genetic background of PD patients could be invaluable resources for understanding PD pathophysiology and for advancing the complexity of in vitro models with 3D expandable organoids.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Mi ‐Young Son, Hyuna Sim, Ye Seul Son, Kwang Bo Jung, Mi‐Ok Lee, Jung‐Hwa Oh, Sun‐Ku Chung, Cho‐Rok Jung, Janghwan Kim Tags: Original Article Source Type: research

Glial papillary tumour of the spinal cord with SMARCB1/INI1 ‐loss and favourable long‐term outcome
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Martin Hasselblatt, Anastasia Dewi Kurniawan, Stephanie Rozsnoki, Pascal D. Johann, Susanne Bens, Florian Oyen, Reinhard Schneppenheim, Reiner Siebert, David Capper, Marcel Kool, Christoph Schul, Werner Paulus Tags: Scientific Correspondence Source Type: research

Frontotemporal lobar degeneration ‐TDP with ‘multiple system atrophy phenocopy syndrome’
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Ana Lu ísa Sousa, Ricardo Taipa, Niall Quinn, Tamas Revesz, Manuel Melo Pires, Marina Magalhães Tags: Scientific Correspondence Source Type: research

Locus coeruleus at asymptomatic early and middle Braak stages of neurofibrillary tangle pathology
ConclusionsComplex alteration of several metabolic pathways occurs in the LC accompanying NFT formation at early and middle asymptomatic stages of NFT pathology. Dopaminergic/noradrenergic denervation and increased expression of α2A adrenergic receptor in the hippocampus and amygdala occur at first stages of NFT pathology, suggesting compensatory activation in the face of decreased adrenergic input occurring before clinical evidence of cognitive impairment and depression.This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Pol Andr és‐Benito, Victor Fernández‐Dueñas, Margarita Carmona, Luis Alberto Escobar, Benjamín Torrejón‐Escribano, Ester Aso, Francisco Ciruela, Isidro Ferrer Tags: Original Article Source Type: research

Myopathology in times of modern imaging
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Heinz Jungbluth Tags: Invited Review Source Type: research

Review: Integrated classification of inflammatory myopathies
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Y. Allenbach, O. Benveniste, H ‐H. Goebel, W. Stenzel Tags: Invited Review Source Type: research

Review: Tau in biofluids ‐ relation to pathology, imaging and clinical features
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Henrik Zetterberg Tags: Invited Review Source Type: research

Commentary on Human adult neurogenesis across the ages: An immunohistochemical study
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Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Gianluca Marucci Tags: Letter to the Editor Source Type: research

Review: Myopathology in the times of modern genetics
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Markus Schuelke, Nancy Christine Øien, Anders Oldfors Tags: Invited Review Source Type: research

K27M midline gliomas display malignant progression by imaging and histology
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Franziska J. Vettermann, Julia E. Neumann, Bogdana Suchorska, Peter Bartenstein, Armin Giese, Mario M. Dorostkar, Nathalie L. Albert, Ulrich Sch üller Tags: Scientific Correspondence Source Type: research

Globular glial inclusions unveil enigmas of MAPT mutations
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Gabor G. Kovacs Tags: Editorial Source Type: research

Myopathology in Congenital Myopathies
This article is protected by copyright. All rights reserved. (Source: Neuropathology and Applied Neurobiology)
Source: Neuropathology and Applied Neurobiology - November 30, 2016 Category: Neurology Authors: Caroline A Sewry, Carina Wallgren ‐Pettersson Tags: Invited Review Source Type: research

Review: Roles for astrocytes in epilepsy: insights from malformations of cortical development
Malformations of cortical development (MCDs), such as cortical dysplasia and tuberous sclerosis complex, are common causes of intractable epilepsy, especially in paediatric patients. Recently, mounting evidence points to a common pathology of these disorders. Hyperactivation of mammalian target of rapamycin (mTOR) has been proposed as a central mechanism in most, if not all, MCDs. The transition from mTOR hyperactivation and cellular abnormalities to large‐scale functional changes and seizure is, however, not fully understood. In this article we set out to review currently available information regarding MCD pathology, f...
Source: Neuropathology and Applied Neurobiology - November 26, 2016 Category: Neurology Authors: M. Kielbinski, K. Gzielo, Z. Soltys Tags: Review Source Type: research