Mutation Research Genetic Toxicology and Environmental Mutagenesis This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Genotoxic and mutagenic evaluation of the protective effect of exogenous melatonin in adult rats and their offspring exposed to the insecticides methomyl and cypermethrin during pregnancy
Publication date: Available online 19 October 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Ketsia Sabrina do Nascimento Marinho, Clovis José Cavalcanti Lapa Neto, Ilka Dayane Duarte de Sousa Coelho, Meykson Alexandre da Silva, Maria Eduarda Gomes Melo, Katharine Raquel Pereira dos Santos, Cristiano Aparecido Chagas, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley TeixeiraAbstractExposure of pregnant women to pesticides in an occupational or incidental manner has been pointed out as a possible cause of health problems in newborns. Cypermethrin and methomyl are insecticides who...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - October 20, 2019 Category: Genetics & Stem Cells Source Type: research

Analysis of historical negative control group data from the rat in vivo micronucleus assay
Publication date: Available online 12 October 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): D. P Lovell, M Fellows, J Saul, J Whitwell, L Custer, S Dertinger, P Escobar, R Fiedler, U Hemmann, J Kenny, R Smith, B.M. van der Leede, A ZellerAbstractA database of micronuclei counts for historical negative control data from rat in vivo micronuclei tests performed in 10 different laboratories was established. Data were available from over 4000 negative control rats from 10 laboratories. The mean frequency of micronucleated cells (MN)/1000 cells ranged from 0.44 to 2.22, a 5-fold range. ...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - October 14, 2019 Category: Genetics & Stem Cells Source Type: research

18F-FDG-induced DNA damage, chromosomal aberrations, and toxicity in V79 lung fibroblast cells
Publication date: Available online 11 October 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Tanmoy Mondal, Amit Nautiyal, Milee Agrawal, Deepanjan Mitra, Alpana Goel, Subrata Kumar DeyAbstract18F-FDG PET/CT imaging is used in the diagnosis of diseases, including cancers. The principal photons used for imaging are 511 keV gamma photons resulting from positron annihilation. The absorbed dose varies among body organs, depending on administered radioactivity and biological clearance. We have attempted to evaluate DNA double-strand breaks (DSB) and toxicity induced in V79 lung fibrob...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - October 12, 2019 Category: Genetics & Stem Cells Source Type: research

Editorial Board
Publication date: October 2019Source: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 846Author(s): (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - October 2, 2019 Category: Genetics & Stem Cells Source Type: research

Cytogenotoxic effects of fullerene C60 in the freshwater teleostean fish, Anabas testudineus (Bloch, 1792)
Publication date: Available online 26 September 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Nechat Sumi, Kumari Chidambaran ChitraAbstractIn recent years, carbon nanomaterials, including fullerene C60 is regarded as the building block in nanotechnology because of its widespread use in medicine, industry, cosmetics and commercial products. Despite the special properties, several reports have raised public health concerns due to the unknown and practically unexplored toxic effects of nanomaterials. However, there have been relatively few studies regarding the genotoxic responses o...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - September 28, 2019 Category: Genetics & Stem Cells Source Type: research

Optimization and Validation of Automated Dicentric Chromosome Analysis for Radiological/Nuclear Triage Applications
Publication date: Available online 23 September 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Terri L. Ryan, Maria B. Escalona, Tammy L. Smith, Joseph Albanese, Carol J. Iddins, Adayabalam S. BalajeeAbstractDicentric Chromosome Assay (DCA) is the most preferred cytogenetic technique for absorbed radiation dose assessment in exposed humans. However, DCA is somewhat impractical for triage application owing to its labor intensive and time consuming nature. Although lymphocyte culture for 48 hrs in vitro is inevitable for DCA, manual scoring of dicentric chromosomes (DCs) requires a...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - September 24, 2019 Category: Genetics & Stem Cells Source Type: research

My career development with Ames test: a personal recollection
Publication date: Available online 18 September 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Takehiko NohmiAbstractI first became acquainted with the Ames test at the very beginning of my career in 1978, when my task at the National Institute of Health Sciences (Tokyo) was to screen for mutagenicity of food additives used in Japan, using the Ames test. I also used this test to research the metabolic activation mechanisms of chemical carcinogens, in particular, the analgesic drug, phenacetin. This chemical was not mutagenic in Salmonella typhimurium TA100 with standard 9,000 x g s...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - September 19, 2019 Category: Genetics & Stem Cells Source Type: research

A personally guided tour on some of our data with the Ames Assay—A tribute to Professor Bruce Ames
Publication date: Available online 9 September 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): J. Rueff, A.S. Rodrigues, M. KranendonkAbstractIn contributing to this Special Issue of Mutation Research dedicated to Professor Bruce N. Ames in recognition of his 90th birthday in December 2018, we intend to portray the importance not only of the Ames Salmonella/mammalian-microsome mutagenicity assay in some of our studies over the years, but also the importance of the insight that Bruce Ames brought to the field of genetic toxicology. (Source: Mutation Research Genetic Toxicology and En...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - September 10, 2019 Category: Genetics & Stem Cells Source Type: research

Introducing article numbering to [MUTGEN]
Publication date: Available online 4 September 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - September 5, 2019 Category: Genetics & Stem Cells Source Type: research

Introduction to hCOMET special issue, ‘Comet assay in vitro’
Publication date: Available online 3 July 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Maria Dusinska, Solange Costa, Andrew Collins (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - August 22, 2019 Category: Genetics & Stem Cells Source Type: research

Combined treatment with cisplatin and the tankyrase inhibitor XAV-939 increases cytotoxicity, abrogates cancer-stem-like cell phenotype, and increases chemosensitivity of head-and-neck squamous-cell carcinoma cells
In conclusion, this study elucidated that combination of cisplatin and XAV-939 exerted cytotoxic and genotoxic effect to abrogate CSC mediated chemoresistance in HNSCC in synergistic manner. (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - August 18, 2019 Category: Genetics & Stem Cells Source Type: research

Editorial Board
Publication date: July 2019Source: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 843Author(s): (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - August 15, 2019 Category: Genetics & Stem Cells Source Type: research

The comet assay in human biomonitoring: Technical and epidemiological perspectives
Publication date: July 2019Source: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 843Author(s): Andrew Collins, Mirta Milic, Stefano Bonassi, Maria Dusinska (Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis)
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - August 15, 2019 Category: Genetics & Stem Cells Source Type: research

2,4-Decadienal does not induce genotoxic effects in in vivo micronucleus studies
Publication date: Available online 11 August 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Maria Bastaki, Vivian Lu, Michel Aubanel, Thierry Cachet, Jan Demyttenaere, Maodo Malick Diop, Sylvain Etter, Xing Han, Christie L. Harman, Shim-mo Hayashi, Zena Keig-Shevlin, Gerhard Krammer, Kevin J. Renskers, Jürgen Schnabel, Sean V. TaylorAbstract2,4-Decadienal (E,E-) occurs naturally in foods and is also used as a flavoring ingredient. In vivo micronucleus studies were used to evaluate the potential for 2,4-decadienal to cause genotoxic effects. Male Han Wistar rats were dosed either b...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - August 12, 2019 Category: Genetics & Stem Cells Source Type: research

Are All Bacterial Strains Required by OECD Mutagenicity Test Guideline TG471 Needed?
Publication date: Available online 9 August 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Richard Williams, David M. DeMarini, Leon F. Stankowski, Patricia A. Escobar, Errol Zeiger, Jonathan Howe, Rosalie Elespuru, Kevin P. CrossAbstractThe International Workshop on Genotoxicity Testing (IWGT) meets every four years to seek consensus on difficult or conflicting approaches to genotoxicity testing based upon experience, available data, and analysis techniques. At the 2017 IWGT meeting in Tokyo, one working group addressed the sensitivity and selectivity of the bacterial strains spec...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - August 10, 2019 Category: Genetics & Stem Cells Source Type: research