Journal of Pharmacological and Toxicological Methods This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Drug Safety Africa Meeting Abstracts
Publication date: July–August 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 98Author(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - August 14, 2019 Category: Drugs & Pharmacology Source Type: research

Editorial Board
Publication date: July–August 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 98Author(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - August 14, 2019 Category: Drugs & Pharmacology Source Type: research

Relationship of clinical adverse event reports to models of arrhythmia risk
This study proposes the use of adverse event reports obtained from the FDA Adverse Event Reporting System as a representation of clinical TdP risk. By incorporating these reports into computational models, a more accurate risk prediction may be developed. (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - August 8, 2019 Category: Drugs & Pharmacology Source Type: research

Publisher's Note
Publication date: Available online 24 July 2019Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - July 26, 2019 Category: Drugs & Pharmacology Source Type: research

Reprint of "EEG: Characteristics of drug-induced seizures in rats, dogs and non-human primates"
The objective was to characterize EEG morphologies and premonitory signs in drug-induced seizures in preclinical species. A comparative (inter-species) retrospective analysis for drug-induced seizures recorded by video-telemetry was conducted in rats (n = 53), dogs (n = 195), and non-human primates (n = 234). The most frequent premonitory signs were, in rats, myoclonus (100%), tremors (93%), salivation (75%), partial ptosis (58%) and chewing/bruxism (58%); in dogs, tremors (77%), ataxia/uncoordination (60%), myoclonus (45%), salivation (43%), excessive licking (38%), high vocalization (38%) and decreased activi...
Source: Journal of Pharmacological and Toxicological Methods - July 26, 2019 Category: Drugs & Pharmacology Source Type: research