Journal of Pharmacological and Toxicological Methods This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Assessment of the drug-induced toxicity on left ventricular function by pattern-cultured hiPSC-CMs
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Atsuhiko Naito, Masamichi Ito, Fengying Gao, Akihiro Furuya, Hiroko Izumi-Nakaseko, Mihoko Hagiwara-Nagasawa, Atsushi Sugiyama (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Allowance for diastolic interval distinguishes Na channel block in iPSC-derived cardiomyocytes
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Godfrey Smith, Niall MacQuaide, Jill Nichols (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Sex differences in repolarization reserve, a possible mechanism for sex-related differences in drug-induced QT prolongation and torsades de pointes
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Feng Wei, Chengzhong Cai, Beverly Lyn-Cook, Li Pang (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Wendy Keung, Patrick K. Chan, Peter Backeris, Eugene K. Lee, Nicodemus Wong, Gabriel K. Wong, Camie W. Chan, Bernard Fermini, Kevin D. Costa, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Modeling cardiac dysfunction of Friedreich's ataxia using ventricular sheets, tissues and chambers engineered from human pluripotent stem cells
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Andy O.-T. Wong, Deborah K. Lieu, Gabriel K. Wong, Bimal Gurung, Wan Wai Tse, Kevin D. Costa, Camie W. Chan, Joseph D. Nabhan, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Directly visualizing drug-induced arrhythmias with aligned human pluripotent stem cell-based ventricular cardiac anisotropic sheet
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Angie Shum, Andy O.-T. Wong, Camie W. Chan, Kevin D. Costa, Michelle Khine, Chi-Wing Kong, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Automated drug classification by machine learning analysis of drug screening data from human pluripotent stem cell-derived engineered cardiac tissue assays
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Eugene K. Lee, David D. Tran, Wendy Keung, Patrick K. Chan, Gabriel K. Wong, Camie W. Chan, Kevin D. Costa, Michelle Khine, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

“Human heart-in-a-Jar”: An electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Ronald A. Li, Wendy Keung, Timothy Cashman, Peter Backeris, Bryce V. Johnson, Evan S. Bardot, Andy O.-T. Wong, Patrick K. Chan, Camie W. Chan, Kevin D. Costa (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Controlled physiomimetic preload augments inotropic sensitivity and contractile phenotypes in human pluripotent stem cell-derived engineered cardiac tissues and chambers
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Andy O.-T. Wong, Camie W. Chan, Kevin D. Costa, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Scaling human ventricular cardiac chamber models for preclinical screening and monitoring of organ-level pump function
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): David D. Tran, Eugene K. Lee, Kevin D. Costa, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Modeling the congenital heart condition of pulmonary atresia with intact ventricular septum using human induced pluripotent stem cells
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Wendy Keung, Yin Yu Lam, Chun Ho Chan, Lin Geng, Yiu-Fai Cheung, Ronald A. Li (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Novel high-throughput human cells-based co-culture screen for chemotherapeutics induced neurotoxicity
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Anup Dutt Sharma, Laurie McCoy, Hannah Willey, Hieu Nguyen, Lowry Curley, Michael Moore (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

A patient-centric CRISPR-Cas9 in vitro cardiovascular safety model to examine genetic variability in calcium handling and its impact on drug-induced cardiotoxicity
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Linda Starnes, Andrew Hall, Anna-Lina Cavallo, Damla Etal, Shailesh Gupta, Caroline Hirst, Ellinor Hornberg, Marcello Maresca, Ryan Hicks, Amy Pointon (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Bridging HTS Ion channel and myocyte data
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Atsushi Ohtsuki, Sonja Stoelzle-Feix, Tim Strassmaier, George Okeyo, Corina Bot, Krisztina Juhasz, Nadine Becker, Ulrich Thomas, Leo Doerr, Markus Rapedius, Nina Brinkwirth, Claudia Haarmann, Tom Goetze, Matthias Beckler, Michael George, Niels Fertig (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research

Utilization of human induced pluripotent stem cell-derived cardiomyocytes on an MEA platform for prediction of liabilities with chronic drug treatment
Publication date: September–October 2019Source: Journal of Pharmacological and Toxicological Methods, Volume 99Author(s): Christopher J. Strock (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - November 1, 2019 Category: Drugs & Pharmacology Source Type: research