A stable cell line inducibly expressing hERG1a/1b heteromeric channels
Publication date: Available online 29 May 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Erick B. Ríos-Pérez, Fang Liu, Whitney A. Stevens-Sostre, Catherine A. Eichel, Jonathan Silignavong, Gail A. Robertson (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Editorial Board
Publication date: May–June 2021Source: Journal of Pharmacological and Toxicological Methods, Volume 109Author(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - May 15, 2021 Category: Drugs & Pharmacology Source Type: research

Use of automated patch clamp in cardiac safety assessment: Past, present and future perspectives
Publication date: Available online 5 May 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Damian C. Bell, Bernard Fermini (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - May 5, 2021 Category: Drugs & Pharmacology Source Type: research

l-citrulline: A preclinical safety biomarker for the small intestine in rats and dogs in repeat dose toxicity studies
Publication date: Available online 1 May 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Sven Jäckel, Frederic Christian Pipp, Barbara Emde, Stefan Weigt, Enrico Vigna, Bettina Hanschke, Lena Kasper, Anindya Siddharta, Jürgen Hellmann, Stephanie Czasch, Michael W. Schmitt (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - May 1, 2021 Category: Drugs & Pharmacology Source Type: research

Mouse models for actinic keratoses
Publication date: Available online 30 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Justin Choi, Cameron E. West, Youkyung S. Roh, Nishadh Sutaria, Shawn G. Kwatra, Madan M. Kwatra (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 30, 2021 Category: Drugs & Pharmacology Source Type: research

The 2-year rodent bioassay in drug and chemical carcinogenicity testing: Panorama of its concordance, utility, configuration, and provisional regulatory role
Publication date: Available online 25 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Jose D. Suarez-Torres, Camilo Orozco, Carlos E. Ciangherotti (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 25, 2021 Category: Drugs & Pharmacology Source Type: research

Efficient and modified 2-NBDG assay to measure glucose uptake in cultured myotubes
Publication date: Available online 20 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Manju Bala, Prachi Gupta, Sanjeev Gupta, Anita Dua, Elisha Injeti, Ashwani Mittal (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 21, 2021 Category: Drugs & Pharmacology Source Type: research

The in vivo QTc core assay: An evaluation of QTc variability, detection sensitivity and implications for the improvement of conscious dog and non-human primate telemetry studies
Publication date: Available online 20 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Joel Baublits, Hugo M. Vargas, Michael J. Engwall (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 21, 2021 Category: Drugs & Pharmacology Source Type: research

Editorial Board
Publication date: March–April 2021Source: Journal of Pharmacological and Toxicological Methods, Volume 108Author(s): (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 14, 2021 Category: Drugs & Pharmacology Source Type: research

Automated blood sampling in canine telemetry studies: Enabling enhanced assessments of cardiovascular liabilities and safety margins
Publication date: Available online 7 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Yevgeniya E. Koshman, Amanda S. Wilsey, Brandan M. Bird, Sabine Sadilek, Debra A. Weisbecker, Paige A. Ebert, James S. Polakowski, Gary A. Gintant, Scott W. Mittelstadt, C. Michael Foley (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 9, 2021 Category: Drugs & Pharmacology Source Type: research

Cell-based actin polymerization assay to analyze chemokine inhibitors
Publication date: Available online 2 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Victoria I. Engemann, Ina Rink, Michelle F. Kilb, Maximilian Hungsberg, Dorothea Helmer, Katja Schmitz (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 3, 2021 Category: Drugs & Pharmacology Source Type: research

A novel murine model of pulmonary fibrosis: the role of platelets in chronic changes induced by bleomycin
Publication date: Available online 2 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): R. Carrington, S. Jordan, Y.J. Wong, S.C. Pitchford, C.P. Page (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 3, 2021 Category: Drugs & Pharmacology Source Type: research

Core battery safety pharmacology testing – An assessment of its utility in early drug development
Publication date: Available online 2 April 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Paul Baldrick (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 2, 2021 Category: Drugs & Pharmacology Source Type: research

Optimization of psoriasis mouse models
Publication date: Available online 26 March 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Christina Karamani, Ivi Theodosia Antoniadou, Aikaterini Dimou, Evgenia Andreou, Georgios Kostakis, Asimina Sideri, Andreas Vitsos, Athena Gkavanozi, Ioannis Sfiniadakis, Helen Skaltsa, Georgios Theodoros Papaioannou, Michail Christou Rallis, Howard Maibach (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - April 1, 2021 Category: Drugs & Pharmacology Source Type: research

Optimization of psoriasis-like mouse models: A comparative study
Publication date: Available online 26 March 2021Source: Journal of Pharmacological and Toxicological MethodsAuthor(s): Christina Karamani, Ivi Theodosia Antoniadou, Aikaterini Dimou, Evgenia Andreou, Georgios Kostakis, Asimina Sideri, Andreas Vitsos, Athena Gkavanozi, Ioannis Sfiniadakis, Helen Skaltsa, Georgios Theodoros Papaioannou, Michail Christou Rallis, Howard Maibach (Source: Journal of Pharmacological and Toxicological Methods)
Source: Journal of Pharmacological and Toxicological Methods - March 27, 2021 Category: Drugs & Pharmacology Source Type: research