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Asymptomatic carotid artery disease – What is the evidence for intervention?
Publication date: Available online 3 December 2015 Source:Journal of Indian College of Cardiology Author(s): Rajsrinivas Parthasarathy, Vipul Gupta Strong evidence exists in favor of revascularization in symptomatic carotid artery stenosis. Contrarily, no unified consensus exits on the best management strategy in asymptomatic carotid artery disease. Early trials on carotid revascularization in asymptomatic stenosis suggested an absolute benefit in favor of intervention. However, with the advent in aggressive medical therapy, rate of stroke/TIA in the territory of asymptomatic stenosis is small and has dropped to ap...
Source: Journal of Indian College of Cardiology - December 5, 2015 Category: Cardiology Source Type: research

How should we manage subclavian vein thrombosis?
Publication date: Available online 4 December 2015 Source:Journal of Indian College of Cardiology Author(s): Saroj Das Subclavian vein thrombosis is a rare condition affecting 1-2 per 100,000 population. While thrombolysis and anticoagulation remain the main stay of treatment for subclavian vein thrombosis due to feeding lines and Hickman's lines, treatment of this condition due to thoracic outlet compression involves a different approach. Better understanding of the pathophysiology of subclavian vein thrombosis has led to staged management with improved outcome. In this brief review I have looked at the current know...
Source: Journal of Indian College of Cardiology - December 5, 2015 Category: Cardiology Source Type: research

New oral anticoagulants
Publication date: Available online 4 December 2015 Source:Journal of Indian College of Cardiology Author(s): Saroj Das The quest for finding an ideal anticoagulant that can replace the commonly used VKA (warfarin) continues. There is now a plethora of data regarding the safety and efficacy of newer oral anticoagulants (NOAC) compared to warfarin for wide ranging clinical indications. These NOACs fall into 2 distinct categories due to their specific targeted action - Factor Xa Inhibitors and Thrombin Inhibitors. Rivaroxaban, Apixaban and Edoxaban belong to the group of Factor Xa Inhibitors while Dabigatran remain the ...
Source: Journal of Indian College of Cardiology - December 5, 2015 Category: Cardiology Source Type: research

Review of treatment for varicose veins
Publication date: Available online 4 December 2015 Source:Journal of Indian College of Cardiology Author(s): Saroj Das Varicose veins affect 20-25% of the general population in the UK. Open surgery dominated the treatment approach until the end of the millennium with variable outcome. During the last 15 years minimally invasive endovenous approach have been developed with better overall result. Many of these newer methods have been tested through large scale clinical trials with promising result. In this review I have analysed the treatment outcome comparing radiofrequency ablation, laser ablation, open surgical proc...
Source: Journal of Indian College of Cardiology - December 5, 2015 Category: Cardiology Source Type: research

Coronary aneurysms and coronary arterial bypass graft disease as initial presentation of Takayasu's arteritis, induced by hepatitis B infection
Discussion The case highlights the diverse modes of presentation of Takayasu's arteritis. Our case presented as acute coronary syndrome with multiple coronary aneurysms and bypass graft disease, which was successfully treated with angioplasty and stenting. The case also highlights the importance of viral infections and vaccinations in the pathogenesis of Takayasu's arteritis. (Source: Journal of Indian College of Cardiology)
Source: Journal of Indian College of Cardiology - October 9, 2015 Category: Cardiology Source Type: research