Journal of Diabetes Science and Technology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Comprehensive Evaluation of a Novel Color Range Indicator in Multiple Blood Glucose Meters Demonstrates Improved Glucose Range Interpretation and Awareness in Subjects With Type 1 and Type 2 Diabetes
Conclusion: Interaction with a CRI improved the ability of subjects with T1 and T2DM to interpret and categorize BG values into recommended glycemic ranges, irrespective of the glucose meter providing the CRI insights. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Grady, M., Katz, L. B., Cameron, H., Levy, B. L. Tags: Original Articles Source Type: research

A Comprehensive Performance Evaluation of Five Blood Glucose Systems in the Hypo-, Eu-, and Hyperglycemic Range
Conclusions: This 3 range glucose clamp approach enables a systematic performance evaluation of BG systems under controlled and reproducible conditions. The random error of the tested BG systems was comparable, but some showed a lower systematic error than others. These BG systems allow an accurate glucose measurement at low, normal and high BG levels. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Zijlstra, E., Heinemann, L., Fischer, A., Kapitza, C. Tags: Original Articles Source Type: research

Long-Term Performance of Point-of-Care Hemoglobin A1c Assays
Conclusions: All who rely on POC methods as well as on central laboratory measurement of HbA1c must understand the potential limitations of these assays. The assessment of diabetes blood sugar control should proceed from the evaluation of HbA1c combined with review of plasma glucose and of self-monitored blood glucose values. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Paknikar, S., Sarmah, R., Sivaganeshan, L., Welke, A., Rizzo, A., Larson, K., Rendell, M. Tags: Original Articles Source Type: research

Glycated Hemoglobin, Plasma Glucose, and Erythrocyte Aging
Conclusions: RBC turnover seems to be dominated by a constant rate of cell loss, and a mechanism that targets cells of a specific age. Average RBC life span is 80 ± 10.9 days. Of HbA1c change toward treatment goal value, 50% is reached in about 30 days. Many factors contribute to the ratio of glycated hemoglobin, yet we can make accurate estimations considering only the in vivo glycation constant, MBG, and the age distribution of erythrocytes. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Beltran del Rio, M., Tiwari, M., Amodu, L. I., Cagliani, J., Rodriguez Rilo, H. L. Tags: Original Articles Source Type: research

First Clinical Experience with Retrospective Flash Glucose Monitoring (FGM) Analysis in South Africa: Characterizing Glycemic Control with Ambulatory Glucose Profile
Conclusions: Using AGP, the characteristics of glucose exposure, variability, stability, and hypoglycemia risk and occurrence were obtained within a short time and with minimal provider and patient input. In a survey at the time of the follow-up visit, clinicians indicated that aggregated AGP data analysis provided important new clinical information and insights. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Distiller, L. A., Cranston, I., Mazze, R. Tags: Original Articles Source Type: research

Evaluation of the Effect of Carbohydrate Intake on Postprandial Glucose in Patients With Type 1 Diabetes Treated With Insulin Pumps
This study evaluates the effect of carbohydrate intake on glycemic control and postprandial blood glucose concentrations. Methods: Insulin pump data from 148 adults with type 1 diabetes, trained in functional insulin therapy, using pumps for ≥6 months, with ≥2 weeks of consecutive downloaded data, ≥80% use of a bolus calculator, ≥3 capillary blood glucose tests/day, and a concurrent HbA1C, were analyzed. More detailed periprandial data (pre- and postmeal glucose, carbohydrate intake, insulin bolus) were collected from a subset of 105 downloads (3495 meals). Results: Mean (± SD) age of contributors was ...
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: James, M. L., Green, L., Amiel, S. A., Choudhary, P. Tags: Original Articles Source Type: research

Diabetes Educators Intended and Reported Use of Common Diabetes-Related Technologies: Discrepancies and Dissonance
Conclusions: Discrepancies and dissonance appear between diabetes educators’ intentions and behavior (intentions to use and reported technology use). Intentions were higher than current use, which was relatively low and not likely to provide significant support to people with type 1 diabetes for disease management, communication, and engagement with health care services. Continuing education and experiential learning may be key in supporting diabetes educators to align their intentions with their practice. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: James, S., Perry, L., Gallagher, R., Lowe, J. Tags: Original Articles Source Type: research

Early Detection of Infusion Set Failure During Insulin Pump Therapy in Type 1 Diabetes
Conclusion: The proposed method for early detection of infusion set failure based on glucose sensor and insulin data demonstrated favorable results on retrospective data and may be implemented as an additional safeguard in a future fully automated closed-loop system. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Cescon, M., DeSalvo, D. J., Ly, T. T., Maahs, D. M., Messer, L. H., Buckingham, B. A., Doyle, F. J., Dassau, E. Tags: Original Articles Source Type: research

Hypoglycemia-Induced Changes in the Electroencephalogram: An Overview
Hypoglycemia is defined by an abnormally low blood glucose level. The condition develops when rates of glucose entry into the systematic circulation are reduced relative to the glucose uptake by the tissues. A cardinal manifestation of hypoglycemia arises from inadequate supply of glucose to the brain, where glucose is the primary metabolic fuel. The brain is one of the first organs to be affected by hypoglycemia. Shortage of glucose in the brain, or neuroglycopenia, results in a gradual loss of cognitive functions causing slower reaction time, blurred speech, loss of consciousness, seizures, and ultimately death, as the h...
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Blaabjerg, L., Juhl, C. B. Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research

Continuous Glucose Monitoring: Impact on Hypoglycemia
This article provides an overview of the hypoglycemia outcomes of randomized controlled trials that investigate the effect of real-time continuous glucose monitoring alone or sensor-augmented pump therapy with a (predictive) low glucose suspend feature. Furthermore, several possible explanations are provided why trials have not shown a reduction in severe hypoglycemia. In addition, existing evidence is presented of real-time continuous glucose monitoring in patients with impaired awareness of hypoglycemia who have the highest risk of severe hypoglycemia. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: van Beers, C. A. J., DeVries, J. H. Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research

Glycemic Control Indices and Their Aggregation in the Prediction of Nocturnal Hypoglycemia From Intermittent Blood Glucose Measurements
Conclusion: The proposed approach shows potential to be used in telemedicine systems for NH prediction. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Sampath, S., Tkachenko, P., Renard, E., Pereverzev, S. V. Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research

Hypoglycemia Detection and Carbohydrate Suggestion in an Artificial Pancreas
Fear of hypoglycemia is a major concern for many patients with type 1 diabetes and affects patient decisions for use of an artificial pancreas system. We propose an alternative way for prevention of hypoglycemia by issuing predictive hypoglycemia alarms and encouraging patients to consume carbohydrates in a timely manner. The algorithm has been tested on 6 subjects (3 males and 3 females, age 24.2 ± 4.5 years, weight 79.2 ± 16.2 kg, height 172.7 ± 9.4 cm, HbA1C 7.3 ± 0.48%, duration of diabetes 209.2 ± 87.9 months) over 3-day closed-loop clinical experiments as part of a multivariable art...
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Turksoy, K., Kilkus, J., Hajizadeh, I., Samadi, S., Feng, J., Sevil, M., Lazaro, C., Frantz, N., Littlejohn, E., Cinar, A. Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research

Long-Term Prediction of Severe Hypoglycemia in Type 1 Diabetes: Is It Really Possible?
Conclusions: Long-term prediction of severe hypoglycemia in type 1 diabetes was not possible, although baseline hypoglycemia unawareness tended to remain a predictor for risk of SH at follow-up. Therefore, it is important repeatedly to assess the different risk factors of SH to determine the actual risk. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Henriksen, M. M., Faerch, L., Thorsteinsson, B., Pedersen-Bjergaard, U. Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research

Hypoglycemia-Associated EEG Changes in Prepubertal Children With Type 1 Diabetes
Conclusions: We found significant differences in the qEEG in euglycemia and hypoglycemia both during daytime and during sleep. The algorithm developed for adults detected hypoglycemia in all children during daytime. The algorithm had too many false alarms during the night because it was more sensitive to deep sleep EEG patterns than hypoglycemia-related EEG changes. An algorithm for nighttime EEG is needed for accurate detection of nocturnal hypoglycemic episodes in children. This study indicates that a hypoglycemia alarm may be developed using real-time continuous EEG monitoring. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Hansen, G. L., Foli-Andersen, P., Fredheim, S., Juhl, C., Remvig, L. S., Rose, M. H., Rosenzweig, I., Beniczky, S., Olsen, B., Pilgaard, K., Johannesen, J. Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research

Efficacy of an Overnight Predictive Low-Glucose Suspend System in Relation to Hypoglycemia Risk Factors in Youth and Adults With Type 1 Diabetes
Conclusions: The PLGS system tested in this study effectively reduced hypoglycemia without a meaningful increase in hyperglycemia across a variety of factors. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - October 31, 2016 Category: Endocrinology Authors: Calhoun, P. M., Buckingham, B. A., Maahs, D. M., Hramiak, I., Wilson, D. M., Aye, T., Clinton, P., Chase, P., Messer, L., Kollman, C., Beck, R. W., Lum, J., for the In Home Closed Loop Study Group Tags: Guest Editors: Wayne Bequette, Bruce Buckingham, Jesper Fleischer, and Brian Frier Source Type: research