CGM Versus FGM; or, Continuous Glucose Monitoring Is Not Flash Glucose Monitoring
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - September 1, 2015 Category: Endocrinology Authors: Heinemann, L., Freckmann, G. Tags: Editorial Source Type: research

Model Predictive Control for Type 1 Diabetes Based on Personalized Linear Time-Varying Subject Model Consisting of Both Insulin and Meal Inputs: An in Silico Evaluation
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Wang, Q., Xie, J., Molenaar, P., Ulbrecht, J. S. Tags: Letters to the Editor Source Type: research

Evaluation of Patient Satisfaction After Using Prefilled Insulin Pen in Real Life in Lithuania
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Radzeviciene, L., Apanaviciene, D. A. Tags: Letters to the Editor Source Type: research

Usability of the Gla-300 Injection Device Compared With Three Other Commercialized Disposable Insulin Pens: Results of an Interview-Based Survey
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Klonoff, D., Nayberg, I., Erbstein, F., Cali, A., Brulle-Wohlhueter, C., Haak, T. Tags: Letters to the Editor Source Type: research

ISO 15197:2013 Accuracy Evaluation of Two CE-Marked Systems for Self-Monitoring of Blood Glucose
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Jendrike, N., Rittmeyer, D., Pleus, S., Baumstark, A., Haug, C., Freckmann, G. Tags: Letters to the Editor Source Type: research

Holistic Impact of Closed-Loop Technology on People With Type 1 Diabetes
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Young, A. J., Thabit, H., Heller, S. R., Evans, M. L., Amiel, S. A., Hovorka, R., Barnard, K. D. Tags: Letters to the Editor Source Type: research

Intentional Large Insulin Overdose Captured on a Continuous Glucose Monitor: A Novel Case Report
(Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: El-Laboudi, A. H., Misra, S., Martineau, M., Deol, P., Sanders, A., Oliver, N. Tags: Letters to the Editor Source Type: research

PsychDT Working Group: Report Psychosocial Aspects of Artificial Pancreas Systems
Conclusions: This working group will serve as a platform to foster exchange, identify research needs, and guide and initiate collaborative research laying the groundwork for optimal utilization of diabetes technology in clinical diabetes care. A close collaboration among all key stakeholders is crucial to ensure that devices are designed, trialed, approved, and provided with minimal user burden and maximum beneficial effect. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Barnard, K. D., Venkat, M. V., Close, K., Heinemann, L., Weissberg-Benchell, J., Hood, K. K., Kubiak, T., Kowalski, A. J., Laffel, L. Tags: Proceedings of Meetings/Conferences Source Type: research

Does Visceral Fat Estimated by Dual-Energy X-ray Absorptiometry Independently Predict Cardiometabolic Risks in Adults?
Conclusions: Without requiring additional CT or MRI-based measurements, visceral fat detected by DXA might offer certain advantages over the traditional DXA adiposity parameters as means of assessing cardiometabolic risks. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Sasai, H., Brychta, R. J., Wood, R. P., Rothney, M. P., Zhao, X., Skarulis, M. C., Chen, K. Y. Tags: Obesity Technology Source Type: research

Technology to Reduce Hypoglycemia
This article reviews technological strategies, from simple to more advanced technologies, which may help prevent or mitigate exposure to hypoglycemia. More efficient insulin delivery systems, bolus advisor calculators, data downloads providing information on glucose trends, continuous glucose monitoring with alarms warning of hypoglycemia, predictive algorithms, and finally closed loop insulin delivery systems are reviewed. The building blocks to correct use and interpretation of this range of available technology require patient education and appropriate patient selection. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Yeoh, E., Choudhary, P. Tags: Review Articles Source Type: research

Performance of Cleared Blood Glucose Monitors
Cleared blood glucose monitor (BGM) systems do not always perform as accurately for users as they did to become cleared. We performed a literature review of recent publications between 2010 and 2014 that present data about the frequency of inaccurate performance using ISO 15197 2003 and ISO 15197 2013 as target standards. We performed an additional literature review of publications that present data about the clinical and economic risks of inaccurate BGMs for making treatment decisions or calibrating continuous glucose monitors (CGMs). We found 11 publications describing performance of 98 unique BGM systems. 53 of these 98...
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Klonoff, D. C., Prahalad, P. Tags: Review Articles Source Type: research

Analytical Performance Requirements for Systems for Self-Monitoring of Blood Glucose With Focus on System Accuracy: Relevant Differences Among ISO 15197:2003, ISO 15197:2013, and Current FDA Recommendations
In the European Union (EU), the ISO (International Organization for Standardization) 15197 standard is applicable for the evaluation of systems for self-monitoring of blood glucose (SMBG) before the market approval. In 2013, a revised version of this standard was published. Relevant revisions in the analytical performance requirements are the inclusion of the evaluation of influence quantities, for example, hematocrit, and some changes in the testing procedures for measurement precision and system accuracy evaluation, for example, number of test strip lots. Regarding system accuracy evaluation, the most important change is...
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Freckmann, G., Schmid, C., Baumstark, A., Rutschmann, M., Haug, C., Heinemann, L. Tags: Review Articles Source Type: research

A Negative Correlation Between Blood Glucose and Acetone Measured in Healthy and Type 1 Diabetes Mellitus Patient Breath
Conclusions: It is well known that the concentration of acetone is strongly influenced by diet, insulin treatment, and so on. Therefore, much more complex analysis with long-term measurements are required. Thus, presented results should be regarded as tentative, and validation studies with the analysis of clinical test and in a large number of patients, including control groups, need to be carried out. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Rydosz, A. Tags: Original Articles Source Type: research

Illustration of Cost Saving Implications of Lower Extremity Nerve Decompression to Prevent Recurrence of Diabetic Foot Ulceration
The US diabetic foot ulcer (DFU) incidence is 3-4% of 22.3 million diagnosed diabetes cases plus 6.3 million undiagnosed, 858 000 cases total. Risk of recurrence after healing is 30% annually. Lower extremity multiple nerve decompression (ND) surgery reduces neuropathic DFU (nDFU) recurrence risk by >80%. Cost effectiveness of hypothetical ND implementation to minimize nDFU recurrence is compared to the current $6.171 billion annual nDFU expense. A literature review identified best estimates of annual incidence, recurrence risk, medical management expense, and noneconomic costs for DFU. Illustrative cost/benefit calcula...
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Rankin, T. M., Miller, J. D., Gruessner, A. C., Nickerson, D. S. Tags: Original Articles Source Type: research

The Effect of a Global, Subject, and Device-Specific Model on a Noninvasive Glucose Monitoring Multisensor System
Conclusions: We demonstrate that the hardware of the 2 devices worn on the left and right arms are consistent yielding similar measured signals and thus glucose estimation results with a global model. The 2 devices also return similar values of glucose errors. These errors are mainly due to nonstationarities in the measured signals that are not solved by the linear model, thus suggesting for more sophisticated modeling approaches. (Source: Journal of Diabetes Science and Technology)
Source: Journal of Diabetes Science and Technology - June 30, 2015 Category: Endocrinology Authors: Caduff, A., Zanon, M., Mueller, M., Zakharov, P., Feldman, Y., De Feo, O., Donath, M., Stahel, W. A., Talary, M. S. Tags: Original Articles Source Type: research