International Journal of STD and AIDS This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

HIV testing rates, prevalence, and knowledge among outpatients in Durban, South Africa: Time trends over four years
The HIV public health messages in South Africa have increased. Our objective was to evaluate changes over time in HIV testing behaviour, prevalence and knowledge. We prospectively enrolled adults (≥18 years) prior to HIV testing at one urban and one peri-urban outpatient department in Durban, South Africa. A baseline questionnaire administered before testing included the number of prior HIV tests and four knowledge items. We used test results to estimate previously undiagnosed HIV prevalence among those tested. We assessed linear trends over enrollment. From November 2006 to August 2010, 5229 subjects enrolled and 4877 ...
Source: International Journal of STD and AIDS - August 1, 2015 Category: Global & Universal Authors: Ramirez-Avila, L., Regan, S., Chetty, S., Giddy, J., Ross, D., Katz, J. N., Freedberg, K. A., Losina, E., Walensky, R. P., Bassett, I. V. Tags: Original research articles Source Type: research

Yaws
is a non-venereal endemic treponemal infection caused by Treponema pallidum sub-species pertenue, a spirochaete bacterium closely related to Treponema pallidum ssp. pallidum, the agent of venereal syphilis. Yaws is a chronic, relapsing disease predominantly affecting children living in certain tropical regions. It spreads by skin-to-skin contact and, like syphilis, occurs in distinct clinical stages. It causes lesions of the skin, mucous membranes and bones which, without treatment, can become chronic and destructive. Treponema pallidum ssp. pertenue, like its sexually-transmitted counterpart, is exquisitely sensitive t...
Source: International Journal of STD and AIDS - August 1, 2015 Category: Global & Universal Authors: Marks, M., Lebari, D., Solomon, A. W., Higgins, S. P. Tags: Review article Source Type: research

UK national guideline for the management of Genital Molluscum in adults, 2014 Clinical Effectiveness Group, British Association for Sexual Health and HIV
(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - August 1, 2015 Category: Global & Universal Authors: Fernando, I., Pritchard, J., Edwards, S. K., Grover, D. Tags: Guidelines Source Type: research

Response to article - R Dabis et al. Do attendees at sexual health and HIV clinics prefer to be called in by name or number? (Int J STD AIDS 2014; 25: 511-515)
(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Carlin, E., Kellock, D. Tags: Letters to the Editor Source Type: research

Response to article - S Seang et al. Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus (Int J STD AIDS 2014; 25: 676-682)
(Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Morgan, M., Brook, G. Tags: Letters to the Editor Source Type: research

Primary syphilis of the oropharynx: an unusual location of a chancre
A 33-year-old man presented with a two-week history of an asymptomatic ulcer of the oropharynx and submandibular lymph nodes swelling. Laboratory examinations were normal, but serological tests revealed positivity for rapid plasma reagin, Treponema pallidum haemagglutination assay and anti-T. pallidum IgM antibodies. Since the patient denied any homosexual relationship, a biopsy of the lesion was performed, which confirmed primary syphilis. The patient received an intramuscular injection of Benzathine Penicillin G (2.4 MU) with complete resolution of the lesion. Extragenital chancres occur in at least 5% of patients with p...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Drago, F., Ciccarese, G., Cogorno, L., Tomasini, C. F., Cozzani, E. C., Riva, S. F., Parodi, A. Tags: Case reports Source Type: research

Successful treatment of refractory Trichomonas vaginalis infection using intravenous metronidazole
Trichomonas vaginalis is a sexually transmitted protozoan infection resulting in a vulvo-vaginitis and altered vaginal discharge in symptomatic women. Since its introduction in the 1960 s, metronidazole has been the first-line drug for trichomonal infection. Other nitroimidazoles, such as tinidazole, are used as alternative regimens with similar activity but at a greater expense. Treatment failure usually represents patient non-compliance or reinfection, although metronidazole resistance has previously been documented. Sensitivity testing is currently not available in the UK. Patients with disease unresponsive to first-lin...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Hawkins, I., Carne, C., Sonnex, C., Carmichael, A. Tags: Case reports Source Type: research

Drug interactions between voriconazole, darunavir/ritonavir and tenofovir/emtricitabine in an HIV-infected patient treated for Aspergillus candidus lung abscess
We report an unusual case of pulmonary aspergillosis in a patient with AIDS and we demonstrated the drug-drug interactions between voriconazole, darunavir/ritonavir and tenofovir/emtricitabine. The combination darunavir-ritonavir-voriconazole should be avoided. (Source: International Journal of STD and AIDS)
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Becker, A., Sifaoui, F., Gagneux, M., Desprez, S., Vignoli, P., Huguet, D., Froidure, M., Leduc, D., Legout, L. Tags: Case reports Source Type: research

Measuring patient satisfaction: three years' data and experience of using a validated patient questionnaire
A validated patient satisfaction questionnaire for use in sexual health clinics was run throughout the southwest region (the UK) three times over three years (13 clinics in January 2012 and 12/13 clinics in January 2013 and the same 12 clinics again in January 2014). The questionnaire covered aspects of pre-appointment, performance of health care professionals, facilities, privacy, respectful communication, information on leaving and overall experience. Data from 1750 questionnaires are presented with means and 95% confidence intervals. Patients under the age of 25 were less likely to rate care as excellent and/or very goo...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Challenor, R., Perry, R. Tags: Original research articles Source Type: research

Self-administered sample collection for screening of sexually transmitted infection among reservation-based American Indian youth
American Indians suffer a disproportionate burden of sexually transmitted infection, particularly adolescents. Screening access barriers in rural and reservation-based communities necessitate alternatives to clinic-based options. Self-administered screening for three sexually transmitted infections was piloted among 32 American Indian adolescents aged 18 to 19. Participants self-collected in a private location; specimens were processed by trained, American Indian paraprofessionals and analysis was conducted by an outside laboratory. Participants testing positive were treated by a Public Health Nurse from the Indian Health ...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Tingey, L., Strom, R., Hastings, R., Parker, A., Barlow, A., Rompalo, A., Gaydos, C. Tags: Original research articles Source Type: research

The performance and clinical utility of cervical microscopy for the diagnosis of gonorrhoea in women in the era of the NAAT
We evaluated the performance and clinical utility of cervical microscopy for diagnosing genital gonorrhoea (GC) in women, using the APTIMA Combo 2 dual GC/Chlamydia trachomatis assay as the gold standard. Test performance was assessed overall and for patient subgroups (symptomatic, GC contacts, pelvic inflammatory disease [PID] diagnosis). It was found that 93 women had positive GC genital NAAT results; 15 had positive cervical microscopy (8 were GC contacts). In all subgroups except GC contacts, the PPV of cervical microscopy was below the nationally accepted target of 90%. Compared to APTIMA Combo 2, cervical microscopy ...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Thorley, N., Radcliffe, K. Tags: Original research articles Source Type: research

The difference between HIV and syphilis prevalence and incidence cases: results from a cohort study in Nanjing, China, 2008-2010
The available estimates of incidence and prevalence of syphilis among men who have sex with men (MSM) in Mainland China are high. We used respondent-driven sampling to recruit MSM in the study population. The participants were followed up to monitor the incidence and change of risk behaviours. A face-to-face interview was used to collect information about high-risk behaviours, demographics and recreational drug use. To test the difference between prevalent and incident cases, two nested matched case-control studies were carried out. The cases were the HIV or syphilis positives found at baseline and during follow-up. We use...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Tang, W., Babu, G. R., Li, J., Zhang, Y., Fu, G., Huan, X., Tucker, J. D., Zhao, J., Detels, R. Tags: Original research articles Source Type: research

Detecting re-infection in patients after an initial diagnosis of gonorrhoea: is routine recall for re-screening useful?
To assess the outcome of routine sexually transmitted infection re-screening after a three-month interval in unselected patients diagnosed with gonorrhoea, we sought to assess whether this active approach would result in an increase in the number of people attending clinic and subsequently diagnosed with gonorrhoea re-infection, compared with normal re-presentation rates. A recall group of patients were invited for re-screening three months after their initial diagnosis of gonorrhoea. Permission was sought to send a reminder two weeks prior to their scheduled recall appointment. Comparisons were made with a historical cont...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Fernando, K., Fowler, T., Harding, J., Flew, S., Caley, M., Phattey, J., Ross, J. Tags: Original research articles Source Type: research

Antiretroviral treatment failure predicts mortality in rural Tanzania
Virological monitoring of HIV-infected patients on antiretroviral treatment (ART) is rarely available in resource-limited settings and many patients experience unrecognized virological failure. We studied the long-term consequences of virological failure in rural Tanzania. Previously, virological efficacy was measured in a cohort treated with ART. In the present study, patients with virological failure (VF; HIV-RNA >400 copies/ml) were followed up and compared to those with virological response (VR; HIV-RNA <400 copies/ml) with regard to mortality, CD4 change and subsequent virological outcome. Fifty-six patients wit...
Source: International Journal of STD and AIDS - July 2, 2015 Category: Global & Universal Authors: Pettersen, P. S., Brox, I. K., Naman, E., Bruun, J. N., Dyrhol-Riise, A. M., Troseid, M., Johannessen, A. Tags: Original research articles Source Type: research