International Journal of Gynecological Cancer This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Surgical Efforts Might Mitigate Difference in Response to Neoadjuvant Chemotherapy in Stage IIIC–IV Unresectable Ovarian Cancer: A Case-Control Multi-institutional Study
Conclusions Complete cytoreduction might mitigate the difference in response to neoadjuvant chemotherapy. The presence of RD at IDS is associated with worse survival outcomes. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Rectosigmoidectomy and Douglas Peritonectomy in the Management of Serosal Implants in Advanced-Stage Ovarian Cancer Surgery: Survival and Surgical Outcomes
Conclusions Douglas peritonectomy showed similar survival and surgical outcomes to RR and provided shorter hospital stay and earlier admission to chemotherapy in the management of serosal implants during advanced-stage ovarian cancer surgery. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Uterine and Tubal Lavage for Earlier Cancer Detection Using an Innovative Catheter: A Feasibility and Safety Study
Conclusions Our studies demonstrate that the UtL, using the new catheter, is a safe, reliable, and well-tolerated procedure, which does not require elaborate training. Therefore, UtL fulfils all prerequisites to be used in a potential screening setting. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Borderline Ovarian Tumors: Fifteen Years’ Experience at a Scottish Tertiary Cancer Center
Conclusions To our knowledge, this study is the largest BOT cohort in the United Kingdom. Recurrent disease is rare in optimally staged, completely resected, early-stage BOT, without high-risk features. Caution is needed in women electing not to undergo completion staging after diagnosis and in those opting for a fertility-preserving approach. Thorough informed consent and clear plans for surveillance and follow-up are needed with consideration of delayed completion surgery as appropriate. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Prognostic Value of Pathologic Chemotherapy Response Score in Patients With Ovarian Cancer After Neoadjuvant Chemotherapy
Conclusions Patients with CRS 3 have longest progression-free survival and highest CA125 drop after NACT. These parameters have important prognostic value and can be used for clinical decision-making. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Intraoperative Ultrasound-Guided Excision of Cardiophrenic Lymph Nodes in an Advanced Ovarian Cancer Patient
Conclusions Intraoperative transdiaphragmatic ultrasound represents a possible approach to localize suspicious CPLNs and to guide their surgical eradication. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Predictive and Prognostic Implication of Bowel Resections During Primary Cytoreductive Surgery in Advanced Epithelial Ovarian Cancer
Conclusions Anastomotic leakage rate after rectosigmoid resection in advanced EOC is acceptably low and outweighs increased perioperative risks when performed in a high-volume institution. Nonetheless, the occurrence of AL is a severe adverse event, which even seems to negatively affect patients’ overall prognosis. As no factor could be identified to clearly predict AL, extensive procedures comprising multiple bowel resections, should be avoided particularly when complete resection cannot be achieved. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Comparison of Laparoscopic and Open Surgery for Patients With Borderline Ovarian Tumors
This study included patients with BOTs who underwent open (n = 433) or laparoscopic (n = 210) surgery between 1990 and 2015. Surgical outcomes, perioperative morbidity, and disease-free survival and overall survival were compared. Results There was no significant difference in age, histologic type of tumor, and laterality of tumor. However, body mass index was slightly higher for the open surgery group (P = 0.046). The open surgery group had a higher serum cancer antigen 125 level (P (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Malignant Transformation of Mature Cystic Teratoma: Is Squamous Cell Carcinoma Different From the Other Types of Neoplasm?
Conclusions Clinical characteristics and outcomes did not differ significantly between SCC and non-SCC. However, chemotherapy regimens differed to some extent, and the possibility of difference in overall survival among pathological types of non-SCC was suggested. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Clinicopathologic Features and Risk Factors for Recurrence of Mucinous Borderline Ovarian Tumors: A Retrospective Study With Follow-up of More Than 10 Years
This study aimed to evaluate the clinicopathologic features of mucinous borderline ovarian tumors (MBOTs), with an emphasis on the risk factors for recurrence. Methods Data of 76 patients with MBOT diagnosed and treated between 2000 and 2007 at a single institution were analyzed in this retrospective study. The clinicopathologic features of different tumor subgroups were analyzed, including pathology, surgical methodology, recurrence, and overall survival. Results The median patient age was 40 years (13–85 years). Forty-six patients with gastrointestinal mucinous borderline tumors (intestinal MBOTs) (73.7%) and 20 ...
Source: International Journal of Gynecological Cancer - November 1, 2018 Category: Cancer & Oncology Tags: Ovarian Cancer Source Type: research

Acute Myeloid Leukemia Following Gynecologic Cancer in the Era of Platinum-Based Chemotherapy
Conclusions Therapy-related AML following chemotherapy treatment for a gynecologic malignancy is a very rare late treatment-related event associated with a poor prognosis. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Quality of Life Source Type: research

Treatment Results and Prognostic Factors of Brain Metastases From Ovarian Cancer: A Single Institutional Experience of 56 Patients
The objective of this study was to describe clinical results of treatment and prognostic factors of patients with brain metastases from ovarian cancer treated at a single institution. Materials and Methods We retrieved information from the electronic medical records of 56 consecutive patients (2.8%) with brain metastases, from a total of 2008 patients with ovarian cancer. Endpoints were the pattern of treatment failure, progression-free survival, and overall survival (OS). Results Radiation was the most common initial treatment for brain metastases (59%), followed by surgery (23%). The median progression-free surviva...
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Uterine Cancer Source Type: research

Endometrial Cancer Presentation and Outcomes Based on Mismatch Repair Protein Expression From a Population-Based Study
The objective was to evaluate clinical characteristics and outcomes of endometrial cancers based on MMR status within a population-based study. Methods This was a retrospective population-based cohort study of all endometrial cancer cases from the Vancouver Coastal Health Authority region, evaluated for 4 MMR proteins using immunohistochemistry from 2012 to 2015. Patients were classified as MMR deficient (dMMR, any MMR protein absent) or MMR proficient (pMMR), Demographics, tumor characteristics, recurrences, and survival rates were compared according to MMR status. Results There were 892 patients, with 650 pMMR (72....
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Uterine Cancer Source Type: research

The Clinical Features of Recurrent Endometrial Cancer in Japan: Chemotherapy Instead of Radiotherapy as Postoperative Adjuvant Treatment
Conclusions Adjuvant chemotherapy was insufficient to reduce the incidence of distant recurrence. The prognosis of patients recurred within regional LN and/or vagina was significantly better than that of patients with recurrence in other lesions because of treatment with surgery and/or radiotherapy. The disease-free interval was a significant prognostic factor for REC patients. (Source: International Journal of Gynecological Cancer)
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Uterine Cancer Source Type: research

Trends and Complications of Vulvar Reconstruction After Vulvectomy: A Study of a Nationwide Cohort
The objective of this study was to determine complications associated with primary closure compared with reconstruction after vulvar excision and predisposing factors to these complications. Methods Patients undergoing vulvar excision with or without reconstruction from 2011 to 2015 were abstracted from the National Surgical Quality Improvement Program database. Common Procedural Terminology codes were used to characterize surgical procedures as vulvar excision alone or vulvar excision with reconstruction. Patient characteristics and 30-day outcomes were used to compare the 2 procedures. Descriptive and univariate stati...
Source: International Journal of Gynecological Cancer - October 1, 2018 Category: Cancer & Oncology Tags: Vulvar Cancer Source Type: research