Association of calpain-10 rs2975760 polymorphism with type 2 diabetes mellitus: a meta-analysis.
Authors: Yan ST, Li CL, Tian H, Li J, Pei Y, Liu Y, Gong YP, Fang FS, Sun BR Abstract Type 2 diabetes mellitus (T2DM) accounts for the majority of diabetes cases and affects a significant proportion of the adult population worldwide. Calpain-10 has been implicated in the development of type 2 diabetes, and some polymorphisms in the CAPN10 gene have been associated with an increased risk of developing this disease. Several molecular epidemiological studies were conducted in recent years to evaluate the association between the CAPN10 rs2975760 polymorphism and T2DM risk in diverse populations. However, the r...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Surgical femorocaval bypass for treating chronic iliac vein occlusion: a case report.
Authors: Hao Q, Ma R, Kang Y, Chen B, Wang B, Zheng Y Abstract Chronic inferior vena cava and iliac vein occlusion, caused by long-term of deep venous thrombosis, will lead to swelling of the limbs, venous claudication and intractable ulcer. However, conservative treatment is often ineffective for vein occlusion. With the development of interventional techniques, endovascular therapy has become the first choice for the treatment of vein occlusion with higher success rate and lower trauma. However, for cases those fail endovascular therapy or for segmental veno-occlusive diseases with low long-term patency ...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Association between polymorphisms and haplotypes of the beta-2 adrenergic receptor gene and asthma in a Chinese Han population.
Authors: Liu ZQ, Jiao Y, Liu CJ, Zhang HC, Hu BR Abstract Conflicting data have been reported on the association of variants of the beta-2 adrenergic receptor (ADRB2) gene with asthma etiology. To provide a scientific basis for the prevention and treatment of asthma, the relationship between single nucleotide polymorphisms and haplotypes of ADRB2 and asthma was examined in a Chinese Han population. Six loci (base positions -2387, -47, 46, 79, 491, and 523) of ADRB2 were examined in a group of individuals with asthma (n = 429) and a control group of individuals who do not have the disease (n = 483). Polymor...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research