Outcome analysis of laporoscopic D1 and D2 dissection in patients 70 years and older with gastric cancer.
CONCLUSIONS: Although extensive dissection had an increased morbidity, there was no significant statistical difference between the two procedures. Early complications should not be attributed only to the extent of LND. The important prognostic factors related to long-time survival are the stage of the tumor, perineural and perivascular invasion, and metastatic lymph nodes. PMID: 25419390 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Does low pentraxin-3 levels associate with polycystic ovary syndrome and obesity?
This study included 64 new diagnosed PCOS patients who had been never treated previously with PCOS and 46 healthy controls with matched age and body mass index (BMI). PTX3, biochemical and hormonal parameters of both groups were measured. The patients were divided into obese and non-obese subgroups according to BMI (above or lower than 25 kg/m²). PTX3, HOMA-IR and high sensitive C-reactive protein (hs-CRP) levels of these subgroups were compared. Serum PTX3 (p=0.013), hs-CRP (p=0.015) and HOMA-IR (p=0.023) levels of PCOS patients were significantly higher than the control group. Serum PTX3 has been found to have negative ...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

The impact of psychiatric disorders with cardiac syndrome X on quality of life: 3 months prospective study.
Authors: Altintas E, Yigit F, Taskintuna N Abstract The aim of the study is to investigate the impact of psychiatric disorders with cardiac syndrome X (CSX) on the patients' quality of life, as well as the efficacy of psychiatric support. Fifty-six CSX and fifty-three Coronary Heart Disease patients were included in the study after coronary angiography. Patients were evaluated right after the angiography and 3 months thereafter. The socio-demographic characteristics, comorbid disorders, Beck Anxiety (BAI), Depression (BDI) Inventory, and Health Related Quality of Life (SF-36) were compared between groups. ...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Inflammatory and bone turnover markers in relation to PTH and vitamin D status among saudi postmenopausal women with and without osteoporosis.
Authors: Al-Daghri NM, Yakout S, Al-Shehri E, Al-Fawaz HA, Aljohani N, Al-Saleh Y Abstract Postmenopausal osteoporosis is characterized by rapid bone loss occurring in the post-menopausal period. The bone loss predominantly involves the trabecular bone and is brought about by an imbalance between the bone remodeling process which can be influenced by factors that could cause or contribute to osteoporosis. Pro-inflammatory cytokines (Il-1β, Il-6, IL-8 and TNF-α) have been implicated in the regulation of bone cells and play a critical role in bone remodeling. They act both directly and indirectly to increa...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Serum resistin levels may be new prognostic factor of crimean-congo hemorrhagic fever.
Authors: Erturk A, Cure E, Parlak E, Cure MC, Yuce S, Kizilkaya B Abstract Crimean-Congo hemorrhagic fever (CCHF) virus can cause potentially fatal infections in humans. During this disease, cytokines are intensive released. Resistin which is a good marker of inflammation is an adipocytokine released from adipose tissue. We aimed to investigate whether serum resistin level in patients with CCHF has a prognostic value in predicting recovery time. Twenty men and 22 women (a total of 42 CCHF patients) and a similar age group of 40 healthy individuals (16 men and 24 women) were included in the study. Hematolog...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Reliability and validity of the Chinese version of reporting of clinical adverse events scale (C-RoCAES).
CONCLUSION: C-RoCAES is applicable to healthcare services of China. The instrument provide information for the providers of healthcare services to develop staff education regarding patient safety, and also help them to evaluate strategies of preventing adverse events in clinical practice in China. PMID: 25419395 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Sperm motility inversely correlates with seminal leptin levels in idiopathic asthenozoospermia.
CONCLUSIONS: The findings indicate a pathophysiological relevance of seminal leptin in sperm motility. PMID: 25419396 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Infertility evaluation via laparoscopy and hysteroscopy after conservative treatment for tubal pregnancy.
CONCLUSION: Factors associated with tubal infertility affect patients who accepted conservative treatment for tubal pregnancy. In patients with a history of a tubal pregnancy, it may be less likely to compromise future reproductive function for conservative-medical treated patients than that for conservative-surgery treated patients. PMID: 25419397 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Safety and efficacy of laparoscopy-assisted gastrectomy for advanced gastric cancer in the elderly.
Authors: Qiu JF, Yang B, Fang L, Li YP, Shi YJ, Yu XC, Zhang MC Abstract To evaluate safety and efficacy of laparoscopy-assisted radical gastrectomy (LARG) for advanced gastric cancer patients aged 70 years or older. Clinical data were retrospectively collected from patients with IIA-IIIC gastric cancer who underwent LARG (n = 30) and open radical gastrectomy (ORG, n = 34) in Department of Gastrointestinal Surgery in the Ningbo First Hospital from January 2012 to December 2013. The mean operative time was longer in the LARG group than in the ORG group but there was no statistical difference between the two...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Flexible intramedullary nailing had better outcomes than kirschner wire fixation in children with distal humeral metaphyseal-diaphyseal junction fracture: a retrospective observational analysis.
Authors: Ge YH, Wang ZG, Cai HQ, Yang J, Xu YL, Li YC Abstract The effectiveness evaluation of flexible intramedullary nailing (FIN) and kirschner wire fixation (K-wire) used for MDJ fractures fixation have been described in multiple reports. But there have been few reports about comparison between FIN and K-wire in children with distal humeral MDJ fracture. In our retrospective study, Nineteen children received K-wire and twenty children received FIN, during the follow-up, six children in the K-wire group and one children in the FIN group was found to have postoperative cubitus varus; fixation method was ...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

MDR-1 gene C/T polymorphism in COPD: data from Aegean part of Turkey.
CONCLUSION: TT genotype of MDR-1 gene was significantly more frequent in COPD patients. MDR-1 gene C/T polymorphism may play a role in COPD development. PMID: 25419400 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Effect of angiogenesis inhibitor SU6668 in combination with 5-Fu on liver metastasis from transplantation tumors of human colorectal cancer in nude mice.
This study was to investigate inhibiting effect of angiogenesis inhibitor SU6668 in combination with 5-Fu on liver metastasis from human colon cancer. Results showed that metastasis rates in SU6668+5-Fu group, SU6668 group, 5-Fu group decreased obviously (P<0.01). Compared with 5-Fu group and control group, microvessel density significantly decreased in SU6668+5-Fu group and SU6668 group (P<0.05). Vascular endothelial growth factor and base fibroblast growth factor reduced obviously in SU6668+5-Fu group, SU6668 group and 5-Fu group compared with control group, and there were significant differences among SU6668+5-Fu ...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

The effect of loaded deep inhale training on mild and moderate COPD smokers.
CONCLUSIONS: Loaded deep inhale exercise has a remarkable effect on improving pulmonary function of mild and moderate COPD. PMID: 25419402 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Successful treatment of a case with pancreatic neuroendocrine carcinoma with focal hepatoid differentiation: a case report and literature review.
Authors: Xin BB, Li JA, Han X, Zhao J, Ji Y, Lou WH, Xu XF Abstract A 33-year-old Chinese woman was admitted to our hospital because of an elevated serum alpha-fetoprotein (AFP) level (300 ng/mL) found in a regular medical checkup. Computed tomography imaging of the abdomen revealed a 1.6 × 2.2 cm low-attenuation mass in the head of the pancreas, with no enlarged lymph nodes and no metastatic liver nodules, and a pancreaticoduodenectomy was performed and the tumor was completely removed. The tumor was solid, unencapsulated and poorly demarcated, measuring 2 × 1.4 × 1.8 cm, and the cut surface was grey-y...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Cyclic thrombocytopenia related to menstrual cycle: a case report and literature review.
Authors: Chen G, Chen L, Qin X, Xie X, Li G, Xu B Abstract Cyclic thrombocytopenia (CTP) is rarely seen and characterized by periodic fluctuations in platelet counts. In some cases, it occurs in phase with menstrual cycle. A 40-year-old female, presented firstly on June 30, 2012, with a 40-day history of appearance of purpuric skin rash and bruising, was readmitted on Aug 14, when she noted bruise on her lips. The platelet count was 24×10(9)/L on June 30, 32×10(9)/L on Aug 14, while it was 161×10(9)/L on July 1, 110×10(9)/L on Aug 16. Physical examination show skin purpuric spots and bruise over the li...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research