International Journal of Clinical and Experimental Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A case report for fatal Churg-Strauss syndrome complications: first reported death due to rapid progression of prominently huge hepatic capsular hematoma and multi-system organ hemorrhage.
We report a unique case of CSS, wherein, an elderly man experienced multiple organ hemorrhage -- a particularly huge hematoma under the capsule of the liver and poor prognosis. PMID: 25419420 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Osteonecrosis of the jaw in patient with denosumab therapy.
This article presents a female patient with mandibular ON related to the use of denosumab. The 55-year-old presented with bone exposure with 8 months of evolution after a dental extraction. The patient began subcutaneous injections of 60 mg denosumab four months prior to the extraction and the lesion remained after the procedure. The patient, with 14 months of follow-up, show mandible ON with no favorable evolution. The clinical condition is presented and the literature of ON associated with denosumab is discussed. PMID: 25419421 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

One-stage anatomic double bundle anterior and posterior cruciate ligament reconstruction.
CONCLUSION: Surgical technical details of one-staged double-bundle reconstruction for ACL and PCL injuries which is gaining popularity recently has been stated. PMID: 25419422 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Immuno-phenotypes and prognosis of acute leukemia in elderly patients.
CONCLUSIONS: These results suggest that CD123(+), CD117(+), CD34(+), and HLA-DR(+) are the factors related with the poor prognosis of elderly patients with acute leukemia. PMID: 25419423 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Factors related to survival rates for breast cancer patients.
This study is to analyze the relationship between clinical parameters and prognosis and survival rates of breast cancer patients. A total of 1541 cases of breast cancer were retrospectively reviewed with respect to clinical parameters and the correlation with prognosis and survival rates. Among these patients, follow-up investigation was performed for 1381 cases. Clinical parameters including disease sites (the lesion quadrant), incidences, the number of axillary lymph node metastasis, maximum diameter of tumor, tumor regional lymph node metastasis (TNM) stages, pathological types were investigated. The estrogen receptor, ...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Essential thrombocytosis accompanied by coagulation factor XII deficiency: a case report.
Authors: Wang Y, Wang Z, Li H, Bi K, Zhu C Abstract Essential thrombocytosis (ET) is a type of myeloproliferative neoplasm with clinical manifestations of thrombosis and hemorrhage, the mechanisms of which remains unclear. Some researches indicated that ET is mainly related to the defect of platelet function and the abnormality of coagulation mechanism. A few reports showed that ET accompanied by acquired hemophilia. However, no evidence of ET with coagulation factor XII deficiency has been published. we here report a case of ET accompanied with coagulation factor XII deficiency, which had clinically signi...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Expression and prognostic value of estrogen receptor beta in breast cancer patients.
This study is to determine the expression of estrogen receptor beta (ERβ) in breast cancer patients and to evaluate its relationship with clinicopathological parameters of breast cancer and its effects on the prognosis of breast cancer patients. Paraffin-embedded primary tumor tissue sections from 490 breast cancer patients were collected consecutively from January 2000 to December 2010. They had complete clinical data and follow-up records. Immunohistochemical staining was conducted to determine ERβ expression. The Kaplan-Meier method was used for survival analysis. Difference in survival was analyzed by the Log-Rank te...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Current status of quality evaluation of nursing care through director review and reflection from the Nursing Quality Control Centers.
CONCLUSION: It is of great realistic significance to ameliorate nursing quality evaluation criteria, modify the evaluation content based on patient needs-oriented idea, adopt scientific evaluation method to evaluate nursing quality, and scientifically and reasonably draw horizontal comparisons of nursing quality between hospitals, as well as longitudinal comparisons of a hospital's nursing quality. These methods mentioned above can all enhance a hospital's core competitiveness and benefit more patients. PMID: 25419427 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Evaluation and identification of microRNA-106 in the diagnosis of cancer: a meta-analysis.
Authors: Zhang B, Xu CW, Shao Y, Wang HT, Wu YF, Song YY, Li XB, Gao WB, Liang WB Abstract Recently, extensive research has identified the non-invasive and cost-effective biomarker microRNA-106 (miR-106) in cancer detection. However, inconsistent results have prevented its usage in clinical. Therefore, we conducted this meta-analysis aimed to systematically determine diagnostic accuracy of miR-106 in distinguishing patients with cancer from cancer-free controls and further evaluate its value serving as a biomarker in clinical. We conducted a systematically literature search in databases (PubMed, web of sci...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Voluntary drinking versus imposed drinking in the methodology of investigations about the drinking-induced thermoregulatory sweating.
CONCLUSION: There exists a difference between voluntary drinking and imposed drinking in the sweating response that follows rehydration. So it is suggested to use the methods of voluntary drinking in the investigations of this phenomenon, to reveal the natural events that happen in the actual circumstances. PMID: 25419429 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Proliferation and migration of hepatoblastoma cells are mediated by IRS-4 via PI3K/Akt pathways.
In conclusion, IRS-4 enhanced the proliferation and migration of the hepatoblastoma cells via PI3K/Akt pathways. PMID: 25419430 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Chronotype and a PERIOD3 variable number tandem repeat polymorphism in Han Chinese pilots.
In this study, we explored the genotype frequency and relationship to the chronotype of a PER3 VNTR polymorphism in Han Chinese pilots compared to other populations to further develop aviation safety research. DNA samples were genotyped with respect to the 4-repeat and 5-repeat alleles of the PER3 VNTR polymorphism. We compared and analyzed PER3 VNTR genotype frequencies of a general Han Chinese population and Han Chinese pilots. The chronotypes of our subjects were evaluated by the morningness-eveningness questionnaire (MEQ). The distribution of PER3 VNTR genotype frequencies from 240 Han Chinese was determined (PER3(4/4)...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

Plasminogen activator inhibitor-1 4G/5G polymorphism is associated with coronary artery disease risk: a meta-analysis.
CONCLUSIONS: This meta-analysis suggested that PAI-1 4G/5G polymorphism was a risk factor for CAD. PMID: 25419432 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

The individualized rehabilitation interventions for dysphagia: a multidisciplinary case control study of acute stroke patients.
CONCLUSION: The findings of present study showed evidence that the individualized rehabilitation interventions carried out by our multidisciplinary rehabilitation professionals provided effective therapeutic effects during the acute stroke dysphagia compared to the conventional rehabilitation interventions, which may shed light on a bright prospect of the individualized rehabilitation interventions in post-stroke dysphagic patients. PMID: 25419433 [PubMed - as supplied by publisher] (Source: International Journal of Clinical and Experimental Medicine)
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research

IL6-174G/C polymorphism and fracture risk.
Authors: Zhang Z, He N, Zhang T Abstract Several studies have examined the associations of polymorphism in interleukin-6 (IL6) with fracture risk. However, the results were conflicting. Thus, a meta-analysis was conducted to determine the relationship between IL6-174C/G polymorphism and risk of fracture. Databases including PubMed, EMBASE, Wanfang were searched. Summary odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were estimated using random-effects models. Six studies were included in this meta-analysis. IL6-174C/G polymorphism was associated with a significantly increased risk of fr...
Source: International Journal of Clinical and Experimental Medicine - December 2, 2014 Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research