A potential influence of vitamin D on HIV infection and bone disease in HIV-positive patients
Publication date: 2013 Source:HIV & AIDS Review, Volume 12, Issue 4 Author(s): Waldemar Misiorowski Vitamin D has long been recognized as essential to the skeletal system. Newer evidence suggests that it also protect against cancer, heart disease, fractures and falls, type 2 diabetes, and depression and play a major role regulating the immune system. Vitamin D polarizes the adaptive immune system away from Th-1 and toward Th-2 responses, and enhances innate immunity. Though vitamin D's anti-viral mechanism has not been fully established, it may be linked to vitamin D's ability to up-regulate the anti-microbial...
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Komentarz do rekomendacji PTN AIDS 2013 – rozpoczynanie i monitorowanie leczenia antyretrowirusowego
Publication date: 2013 Source:HIV & AIDS Review, Volume 12, Issue 4, Supplement Author(s): Piotr Pulik , Andrzej Horban (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Risk perception, HIV/AIDS related knowledge, attitude and practice of the university community: The case of Ethiopian Civil Service College
Conclusions Positive changes in awareness and attitudes toward HIV/AIDS were noted, yet comprehensive knowledge is lacking. An improved strategy to promote comprehensive knowledge and behavioral change interventions is needed in ECSC. Implications from these finding suggest that other institutions may benefit from similar changes. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Vulnerability factors for malnutrition among people living with HIV under antiretroviral treatment in an outpatient clinic: Kinshasa, Democratic Republic of Congo
Conclusions Determining factors underlying vulnerability to malnutrition may be helpful to health providers in poor income settings for more effectively target patient interventions. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Adverse drug reactions of antiretroviral therapy in patients receiving methadone substitution treatment
Conclusion A study found that co-administration of methadone may increase the incidence of adverse effects, which in turn has a significant impact on patient quality of life. This issue has not been fully explained and requires further studies in a larger group of patients. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Interpatient variability of darunavir concentrations in plasma during long-term antiretroviral monotherapy
Conclusions In the above presented results confirmed variability of DRV range concentration in plasma during long-term antiretroviral therapy. The presented HPLC method meets the requirements typical for analytical methods applied in TDM. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Epidemiological trends of cancers in AIDS patients
Publication date: 2014 Source:HIV & AIDS Review, Volume 13, Issue 1 Author(s): Loveleena Agarwal , Amitabh Agarwal Since the advent of highly active antiretroviral therapy (HAART), patients with human immunodeficiency virus (HIV) infection have seen a significant improvement in their morbidity, mortality and life expectancy. The incidence of AIDS-defining illnesses, including AIDS-defining malignancies, has been on the decline. However, deaths due to non-AIDS-defining illnesses have been on the rise. These so-called non-AIDS-defining cancers (NADCs) include cancers of the lung, liver, anus, and Hodgkin's lymp...
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Distinct advancements and challenges in HIV 1 vaccine development and cure—A review
Publication date: 2014 Source:HIV & AIDS Review, Volume 13, Issue 1 Author(s): Sandeep Raja Dangeti HIV vaccine development demands for two crucial needs to be successful; firstly, to identify immunologic vulnerabilities of HIV, and secondly, to develop a vaccine approach that safely and durably exploits such vulnerabilities. Rv144 vaccine trail has laid foundations for identification of HIV vulnerabilities and HIV broadly neutralizing monoclonal antibodies as an approach for the HIV vaccine development. Even though this trail failed, it provided a platform for the extensive research options and challenges fac...
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Two endocrine diseases in one case of immune reconstitution inflammatory syndrome
Publication date: 2014 Source:HIV & AIDS Review, Volume 13, Issue 2 Author(s): Marta Almeida Ferreira , André Couto Carvalho , Sara Vieira Silva , Margarida França , Fátima Borges Highly active antiretroviral therapy (HAART) reduces the incidence of opportunistic events and death in patients with HIV infection, but it may be associated with serious complications, like the immune reconstitution inflammatory syndrome (IRIS). This syndrome can include a wide group of infectious, autoimmune and immune-mediated inflammatory diseases. Endocrine autoimmune diseases are rarely diagnosed in patients with IRIS. T...
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
High CD4 cells count in a naïve HIV-infected patient with disseminated Kaposi sarcoma
In conclusion, KS should be taken into consideration in differential diagnosis even in patients with a high CD4 count. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Family dysfunction among depressed HIV/AIDS patients on HAART, in a secondary health institution, in north central Nigeria
Conclusion Depression is very prevalent among HIV/AID patient. They have low family APGAR score, because family dysfunction is a common problem among them. There was a significant association between depression and family dysfunction. This may partly be responsible for non-disclosure of their HIV/AID status to their family members. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Viral hepatitis B, C and HIV coinfection: Evaluation of some immunological and epidemiological aspects
Conclusion It is important to initiate additional studies on the influence of hepatitis B and C in people infected with HIV on clinical progression of HIV for optimization of epidemiological surveillance measures, especially in endemic for viral hepatitis countries. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Assessment of the usefulness of β2-microglobulin and retinol binding protein for the purpose of testing kidney function in HIV-positive patients
Conclusion β2M and RBP concentrations in urine may become useful in diagnosis of renal failure and are more sensitive than the standard determination of creatinine in plasma and eGFR in patients treated with tenofovir. The determination of the excretion of β2M seems a better measurement of tenofovir nephrotoxicity than RBP. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Molecular epidemiology of HIV in Asia
Publication date: 2014 Source:HIV & AIDS Review, Volume 13, Issue 2 Author(s): Shuvra Kanti Dey , Nazneen Zahan , Sabrina Afrose , Tarequl Islam , Md Shajahan , Suchi Saha , Siraje Arif Mahmud , Ali Azam Talukder , Masashi Mizuguchi , Hiroshi Ushijima Human immunodeficiency virus (HIV) is the worldwide disseminated causative agent of acquired immunodeficiency syndrome (AIDS). HIV is grouped in two types named HIV-1 and HIV-2. Asia is home to 60% of the world's population and to 19% of the men, women and children living with HIV in 2004. Close to a million of people has been infected and a half million...
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
Adherence to single-tablet versus multiple-tablet regimens in the treatment of HIV infection—A questionnaire-based survey on patients satisfaction
Conclusion The efficacy of antiretroviral treatment largely depends on the degree of patient adherence. The study has confirmed greater acceptance of the simplified single-tablet treatment regimen among the patients, which was associated with the greater ease of regularly taking medication and with higher quality of life. In the group of patients receiving multiple-tablet regimens, suboptimal suppression of HIV replication was observed more often, which may negatively affect remote treatment outcomes. Patients treated for HIV infection highly rate the convenience of simplified single-tablet regimens, which is associated wi...
Source: HIV and AIDS Review - November 1, 2014 Category: Infectious Diseases Source Type: research
