Adherence to single-tablet versus multiple-tablet regimens in the treatment of HIV infection—A questionnaire-based survey on patients satisfaction

Conclusion The efficacy of antiretroviral treatment largely depends on the degree of patient adherence. The study has confirmed greater acceptance of the simplified single-tablet treatment regimen among the patients, which was associated with the greater ease of regularly taking medication and with higher quality of life. In the group of patients receiving multiple-tablet regimens, suboptimal suppression of HIV replication was observed more often, which may negatively affect remote treatment outcomes. Patients treated for HIV infection highly rate the convenience of simplified single-tablet regimens, which is associated with improved adherence and improved quality of life. The use of simplified single-tablet regimens may improve treatment efficacy.
Source: HIV and AIDS Review - Category: Infectious Diseases Source Type: research