Exogenous Cushing's syndrome as a result of ritonavir –budesonide interaction – A case report
We describe a case of a 43-year-old woman with HIV infection that presented with a clinical overt CS resulting from the interaction between ritonavir and intranasal budesonide at low doses. Similar cases have been described with long-term concomitant use of many glucocorticoids with ritonavir but very few concerning inhaled or intranasal budesonide. This case reinforces the importance of physicians to be aware of this interaction, promoting its early recognition and providing a careful assessment of potentially serious drug–drug interactions, especially when ritonavir is prescribed to a HIV-patient with bronchial hyperre...
Source: HIV and AIDS Review - June 17, 2016 Category: Infectious Diseases Source Type: research

HIV –TB co-infection and associated risk factors among HIV positive patients at Olabisi Onabanjo University Teaching Hospital, Ogun State, South-West Nigeria
Conclusion Study findings provide evidence of a decline in TB burden over time. However, given the retrospective nature of this study, there is a dire need for a more robust and expanded investigation into the true nature of active TB epidemiology in south-western Nigeria, in order to further our insight and target intervention delivery. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - June 17, 2016 Category: Infectious Diseases Source Type: research

Adherence to antiretroviral therapy and its associated factors among HIV positive patients in Nekemte public health institutions, West Ethiopia
Conclusions Self-reported adherence in this study was higher than that seen in developing countries. Management of depression and opportunistic infections using an alarm clock, nutrition education, encouragement of social support and counseling of the patient to attend their follow up at nearer health care facilities are recommended to improve the adherence level. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - June 8, 2016 Category: Infectious Diseases Source Type: research

Multicentric Castleman Disease and Kaposi sarcoma: Two HHV8 diseases with different prognosis and treatment
Conclusion High clinical suspension is required in cases of cutaneous and lymph node Kaposi sarcoma with diffuse lymphadenopathy and systemic manifestation for early detection and proper treatment of aggressive and possibly fatal MCD. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - June 4, 2016 Category: Infectious Diseases Source Type: research

Efavirenz as component of initial combination antiretroviral therapy – Data from the Polish Observational Cohort of HIV/AIDS Patients (POLCA) Study Group
Conclusions EFV-based cART proved to be effective and safe treatment option for HIV-positive patients observed in POLCA study. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - May 12, 2016 Category: Infectious Diseases Source Type: research

Kaposi sarcoma presenting as “diffuse gingival enlargement”: Report of three cases
Conclusions Patients presenting reddish blue macules, plaques or nodular lesions on the skin or oropharyngeal mucosa, should be suspected for having KS whenever an immunosuppressive therapy is involved. If the patient is not treated by immunosuppressive medications, it is important to determine the HIV status, as it is crucial in the overall management of patients diagnosed with KS. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - May 5, 2016 Category: Infectious Diseases Source Type: research

Peripheral facial palsy leading to the diagnosis of acute HIV infection
We present the case of a patient who developed a peripheral facial palsy and a trigeminal neuralgia during an acute HIV infection, and the laboratory and microbiological findings, including the HIV viral load in CSF, which strongly suggest an HIV primary infection as the etiology of these neuropathies. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - April 19, 2016 Category: Infectious Diseases Source Type: research

Exogenous Cushing's syndrome as a result of ritonavir–budesonide interaction – A case report
We describe a case of a 43-year-old woman with HIV infection that presented with a clinical overt CS resulting from the interaction between ritonavir and intranasal budesonide at low doses. Similar cases have been described with long-term concomitant use of many glucocorticoids with ritonavir but very few concerning inhaled or intranasal budesonide. This case reinforces the importance of physicians to be aware of this interaction, promoting its early recognition and providing a careful assessment of potentially serious drug–drug interactions, especially when ritonavir is prescribed to a HIV-patient with bronchial hyperre...
Source: HIV and AIDS Review - April 13, 2016 Category: Infectious Diseases Source Type: research

Reported quality of life of HIV-positive people in Maseru, Lesotho: The need to strengthen social protection programmes
Conclusion PLWHA in Lesotho are least satisfied with the physical and environmental aspects of their lives. Their QoL is determined by age, level of education, marital status, economic status and level of social support. Lesotho needs to scale up the implementation of social protection policy to improve QoL of PLWHA. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - April 13, 2016 Category: Infectious Diseases Source Type: research

Isolated cryptococcuria in a patient with impaired immunity
We describe isolated cryptococcuria in a patient on chronic corticosteroid therapy for sclerosing mesenteritis that was later found to have metastatic adenocarcinoma as well as combined T- and B-cell deficiency. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - April 4, 2016 Category: Infectious Diseases Source Type: research

Genetic diagnosis of seronegative (HIV−) partner of female patient with AIDS in the context of HIV transmission
Conclusion Genetic diagnosis is not routinely recommended, observation of exposed and uninfected individuals would allow to implement new knowledge into more effective care. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - April 1, 2016 Category: Infectious Diseases Source Type: research

HIV–TB co-infection and associated risk factors among HIV positive patients at Olabisi Onabanjo University Teaching Hospital, Ogun State, South-West Nigeria
Conclusion Study findings provide evidence of a decline in TB burden over time. However, given the retrospective nature of this study, there is a dire need for a more robust and expanded investigation into the true nature of active TB epidemiology in south-western Nigeria, in order to further our insight and target intervention delivery. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - April 1, 2016 Category: Infectious Diseases Source Type: research

Is there an association between African national HIV prevalence values and socio-economic status of their albino populations?
Conclusion There is an association between national HIV prevalence values in Africa and socio-economic status of their albino populations. It shows poverty-stricken African albinos to be apparently more likely to be HIV positive than their normal-pigmented counterparts. Neglecting the special educational needs of this group exposes the general society to danger. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - March 19, 2016 Category: Infectious Diseases Source Type: research

Kawasaki-like disease (KLD) in an adult with congenital HIV infection
Conclusion It is a challenging task to diagnose Kawasaki-like disease in HIV infected adults due to a high likelihood of opportunistic infections or possible hypersensitivity to any one of the plethora of prescribed medications. A high suspicion of KLD is advised in HIV infected adults with severe immunosuppression and unexplained fever lasting>5 days to ensure timely diagnosis and treatment. (Source: HIV and AIDS Review)
Source: HIV and AIDS Review - December 13, 2015 Category: Infectious Diseases Source Type: research

Effectiveness of HIV/AIDS educational intervention in increasing knowledge, attitude and practices for primary school teachers in some part of Africa
Publication date: Available online 1 December 2015 Source:HIV & AIDS Review Author(s): Mustapha Abdu, Ahmad Umar, Bin Hj. Ibrahim Faisal, Syed Hassan Syed Tajuddin, Binti Ismail Suria, Musa Garba Yakasai Human immunodeficiency virus (HIV) is virus that weakens the immune system of the body through destruction of the white blood cells. Whereas, AIDS term as; acquired immune deficiency syndrome is a disease due to the infection of HIV. Knowledge of health, and practices among teachers of primary school are scanty. Studies indicated that few teachers have heard or even became aware that HIV/AIDS is a v...
Source: HIV and AIDS Review - December 1, 2015 Category: Infectious Diseases Source Type: research