Pitfall in immunohistochemical staining for thyroglobulin in case of thyroid metastasis from lung carcinoma
Napatt Kanjanahattakij, Palapong Chayangsu, Wasana Kanoksil, Sasiphat Chontong, Chutintorn SriphrapradangCytoJournal 2015 12(1):27-27 (Source: CytoJournal)
Source: CytoJournal - November 30, 2015 Category: Pathology Authors: Napatt KanjanahattakijPalapong ChayangsuWasana KanoksilSasiphat ChontongChutintorn Sriphrapradang Source Type: research
Human Immunodeficiency Virus-associated primary effusion lymphoma: An exceedingly rare entity in cerebrospinal fluid
We report another case of PEL diagnosed in CSF from a 61-year-old male with Acquired Immunodeficiency Syndrome that presented with neurological symptoms. Imaging studies of his brain showed leptomeningeal/periventricular enhancement, but no mass lesion. His CSF demonstrated human herpesvirus-8 positive pleomorphic lymphoplasmacytoid cells of null cell phenotype. This case highlights that albeit rare, PEL should be included in the differential diagnosis when large atypical cells are encountered in CSF of HIV-positive patients, even when such patients have no history of lymphoma. As in this case, ancillary studies are requir...
Source: CytoJournal - October 23, 2015 Category: Pathology Authors: Sarika JainAlka PalekarSara E MonacoFiona E CraigGhassan BejjaniLiron Pantanowitz Source Type: research
The effectiveness of acetic acid wash protocol and the interpretation patterns of blood contaminated cervical cytology ThinPrep® specimens
Conclusions: While AAW had a significantly higher percent of UNS interpretations, the protocol was effective in rescuing 94.2% of specimens which otherwise may have been reported unsatisfactory. This improved patient care by avoiding a repeat test. The prevalence of ASCUS and HSIL interpretations between AAW and non-AAW groups were comparable. Though not statistically significant, HSIL interpretations were relatively higher in the AAW group. LSIL interpretations showed lower prevalence in AAW group. (Source: CytoJournal)
Source: CytoJournal - October 23, 2015 Category: Pathology Authors: Nora K FrischYasin AhmedSeema SethiDaniel NeillTatyana KalinichevaVinod Shidham Source Type: research
The route of science: Labyrinths and algorithms - Inspirations by human papillomavirus testing and cervical cancer
Mehmet Uhri, Binnur OnalCytoJournal 2015 12(1):24-24 (Source: CytoJournal)
Source: CytoJournal - October 23, 2015 Category: Pathology Authors: Mehmet UhriBinnur Onal Source Type: research
Utility of endobronchial ultrasound-guided-fine-needle aspiration and additional value of cell block in the diagnosis of mediastinal granulomatous lymphadenopathy
Conclusion: Our study supports the use of EBUS-FNA, by virtue of being a safe, minimally invasive, and an outpatient procedure, in the diagnosis of granulomatous mediastinal lymphadenopathy, thereby obviating more invasive testing in a significant number of patients. Also, cell block provides additional data in the diagnosis in these benign mediastinal diseases. (Source: CytoJournal)
Source: CytoJournal - September 22, 2015 Category: Pathology Authors: Shaesta Naseem ZaidiEmad Raddaoui Source Type: research
Etiologic factors related to unsatisfactory ThinPrep® cervical cytology: Evaluation and potential solutions to improve
Conclusion: LUBE was the most common cause of unsatisfactory TP in addition to interference by blood and association with atrophic changes. Knowing the morphological spectrum of LUBE would help to identify it as the cause of "unsatisfactory" TP. Communicating the cause of unsatisfactory TP such as LUBE, ACC, and blood would hint the provider to take appropriate precaution during submission of the repeat specimen, leading to improved patient care. (Source: CytoJournal)
Source: CytoJournal - September 22, 2015 Category: Pathology Authors: Tatyana KalinichevaNora FrischTamar GiorgadzeShashi MadanAnushree ShidhamAmarpreet BhallaLinette Mejias-BadilloPaul TranchidaSudeshna BandyopadhyayInderpreet DhillonVinod B Shidham Source Type: research
Etiologic factors related to unsatisfactory ThinPrep & #174; cervical cytology: Evaluation and potential solutions to improve
Conclusion: LUBE was the most common cause of unsatisfactory TP in addition to interference by blood and association with atrophic changes. Knowing the morphological spectrum of LUBE would help to identify it as the cause of "unsatisfactory" TP. Communicating the cause of unsatisfactory TP such as LUBE, ACC, and blood would hint the provider to take appropriate precaution during submission of the repeat specimen, leading to improved patient care. (Source: CytoJournal)
Source: CytoJournal - September 21, 2015 Category: Pathology Authors: Tatyana Kalinicheva Nora Frisch Tamar Giorgadze Shashi Madan Anushree Shidham Amarpreet Bhalla Linette Mejias-Badillo Paul Tranchida Sudeshna Bandyopadhyay Inderpreet Dhillon Vinod B Shidham Source Type: research
Is DOG1 really useful in the diagnosis of salivary gland acinic cell carcinoma? - A DOG1 (clone K9) analysis in fine needle aspiration cell blocks and the review of the literature
Conclusions: FNA is a common tool in the diagnosis and management of salivary gland tumors. DOG1-K9 clone was very useful with a unique staining pattern of apical-luminal positivity in the differential diagnosis of AciCC from other oncocytic salivary gland tumors. (Source: CytoJournal)
Source: CytoJournal - August 31, 2015 Category: Pathology Authors: Sule CanberkMine OnenerkElif SaymanCeren Canbey GoretMurat ErkanTugba AtasoyGamze Z Kilicoglu Source Type: research
Merkel cell carcinoma presenting as malignant ascites: A case report and review of literature
We describe the cytologic findings as well as the immunohistochemical stains supportive of the diagnosis. Given the fatal prognosis of this tumor compared to melanoma and rarity of its occurrence in ascitic fluid, awareness of this tumor and use of immunohistochemical stains are critical in arriving at the diagnosis. (Source: CytoJournal)
Source: CytoJournal - August 31, 2015 Category: Pathology Authors: Maria Luisa C Policarpio NicolasDiane L AveryTaylor Hartley Source Type: research
Is DOG1 really useful in the diagnosis of salivary gland acinic cell carcinoma ? - A DOG1 (clone K9) analysis in fine needle aspiration cell blocks and the review of the literature
Conclusions: FNA is a common tool in the diagnosis and management of salivary gland tumors. DOG1-K9 clone was very useful with a unique staining pattern of apical-luminal positivity in the differential diagnosis of AciCC from other oncocytic salivary gland tumors. (Source: CytoJournal)
Source: CytoJournal - August 30, 2015 Category: Pathology Authors: Sule Canberk Mine Onenerk Elif Sayman Ceren Canbey Goret Murat Erkan Tugba Atasoy Gamze Z Kilicoglu Source Type: research
Amyloidoma secondary to insulin injection: Cytologic diagnosis and pitfalls
We present a case of amyloidoma associated with insulin injection site found incidentally in an 80-year-old male with multiple co-morbidities who presented with diverticulitis associated bleeding. A subcutaneous abdominal mass was found on physical examination. Imaging revealed a 5 cm Χ 1.6 cm homogenous subcutaneous lesion. A fine-needle aspiration (FNA) and core biopsy were performed under ultrasound guidance to reveal amorphous material proven to be amyloidosis at insulin injection sites (AIns) type amyloid. The patient had no treatment for this lesion and has had his care triaged to his more serious health ...
Source: CytoJournal - July 28, 2015 Category: Pathology Authors: Dianne GrunesAmy RapkiewiczAylin Simsir Source Type: research
Urine cytology: Pitfall due to a "remnant" lesion
Michael Chaump, Tamar Giorgadze, Andrew M SchreinerCytoJournal 2015 12(1):16-16 (Source: CytoJournal)
Source: CytoJournal - July 28, 2015 Category: Pathology Authors: Michael ChaumpTamar GiorgadzeAndrew M Schreiner Source Type: research
Upper tract urinary cytology to detect upper tract urothelial carcinoma: Using the Johns Hopkins Hospital template and evaluation of its feasibility
Conclusions: UT washing cytology has high specificity for detecting UC, especially HGUC. Using JHHT on UT washing cytology is feasible, but the category of LGUC may need modification. (Source: CytoJournal)
Source: CytoJournal - July 28, 2015 Category: Pathology Authors: Longwen ChenHuiying HeMatthew A ZarkaMing ZhouCristina Magi-Galluzzi Source Type: research
Urine cytology: Pitfall due to a " remnant " lesion
Michael Chaump, Tamar Giorgadze, Andrew M SchreinerCytoJournal 2015 12(1):16-16 (Source: CytoJournal)
Source: CytoJournal - July 27, 2015 Category: Pathology Authors: Michael Chaump Tamar Giorgadze Andrew M Schreiner Source Type: research
Amylase crystalloids in fine needle aspiration cytology of parotid gland: A diagnostic challenge
Büsra Y Bayrak, Çigdem Vural, Nadir PaksoyCytoJournal 2015 12(1):12-12 (Source: CytoJournal)
Source: CytoJournal - June 23, 2015 Category: Pathology Authors: Büsra Y BayrakÇigdem VuralNadir Paksoy Source Type: research
