Metastatic mesothelioma to the thyroid
Sarika N. Rao, Archana Swami, Ashraf Khan, Madhavi Toke, Giles Whalen, Andrew Fischer, Mira Sofia TorresCytoJournal 2014 11(1):11-11A 69 year-old male patient with a history of malignant mesothelioma treated with chemotherapy and surgical resection with removal of the right lung and right pleural pneumonectomy was clinically in remission for 1 ½ years. A positron emission tomography (PET) scan revealed limited uptake in the right pleural space, thought to represent post-surgical changes, and uptake in the left thyroid lobe. Thyroid ultrasound revealed a solid left lobe nodule with peripheral vascularity and abs...
Source: CytoJournal - May 22, 2014 Category: Pathology Authors: Sarika N. RaoArchana SwamiAshraf KhanMadhavi TokeGiles WhalenAndrew FischerMira Sofia Torres Source Type: research
Molecular testing guidelines for lung adenocarcinoma: Utility of cell blocks and concordance between fine-needle aspiration cytology and histology samples
Conclusions: Identification of mutations in lung adenocarcinomas affects clinical decision-making, and it is important that results from small samples be accurate. This study demonstrates that molecular testing on cytology CBs is as sensitive and specific as that on histology. (Source: CytoJournal)
Source: CytoJournal - May 22, 2014 Category: Pathology Authors: Jonas J. HeymannWilliam A. BulmanRoger A. MaxfieldCharles A. PowellBalazs HalmosJoshua SonettNike T. BeaubierJohn P. CrapanzanoMahesh M. MansukhaniAnjali Saqi Source Type: research
Verification bias is common in cytopathology studies on diagnostic accuracy
Robert L. SchmidtCytoJournal 2014 11(1):13-13 (Source: CytoJournal)
Source: CytoJournal - May 22, 2014 Category: Pathology Authors: Robert L. Schmidt Source Type: research
Is 58% sensitivity for detection of cervical intraepithelial neoplasia 3 and invasive cervical cancer optimal for cervical screening?
R. Marshall Austin, Chengquan ZhaoCytoJournal 2014 11(1):14-14Recent Food and Drug Administration (FDA) approval of a Roche cobas human papillomavirus (HPV) test application as a first line primary cervical screening tool in women 25 and older introduces a new era of complex cervical screening choices. Perhaps the most surprising findings in Roche's supporting ATHENA trial data were the unexpectedly low verification bias-adjusted CIN3+ sensitivities documented by the FDA for both the proposed cobas HPV testing algorithm (58.26%) and Pap testing algorithm (42.63%). These unexpectedly low sensitiv...
Source: CytoJournal - May 22, 2014 Category: Pathology Authors: R. Marshall AustinChengquan Zhao Source Type: research
Is 58 % sensitivity for detection of cervical intraepithelial neoplasia 3 and invasive cervical cancer optimal for cervical screening ?
R. Marshall Austin, Chengquan ZhaoCytoJournal 2014 11(1):14-14Recent Food and Drug Administration (FDA) approval of a Roche cobas human papillomavirus (HPV) test application as a first line primary cervical screening tool in women 25 and older introduces a new era of complex cervical screening choices. Perhaps the most surprising findings in Roche's supporting ATHENA trial data were the unexpectedly low verification bias-adjusted CIN3+ sensitivities documented by the FDA for both the proposed cobas HPV testing algorithm (58.26%) and Pap testing algorithm (42.63%). These unexpectedly low sensitiv...
Source: CytoJournal - May 21, 2014 Category: Pathology Authors: R. Marshall Austin Chengquan Zhao Source Type: research
Fine-needle aspiration of metastatic renal cell carcinoma to a male breast: A rare initial presentation
Karan Saluja, Beenu Thakral, Esther Bit-Ivan, Michael Kaufman, Lin LiuCytoJournal 2014 11(1):8-8 (Source: CytoJournal)
Source: CytoJournal - April 29, 2014 Category: Pathology Authors: Karan SalujaBeenu ThakralEsther Bit-IvanMichael KaufmanLin Liu Source Type: research
Cytomorphologic spectrum of Hashimoto's thyroiditis and its clinical correlation: A retrospective study of 52 patients
Conclusions: HT is a disease of young and middle age and mostly occur in females. Clinical findings alone may not be adequate for definitive diagnosis. FNA is the gold standard for diagnosis. In the presence of abundant colloid, follicular hyperplasia or co-existing neoplasm, careful interpretation of cytology smears should be done. Aspiration from more than one site minimizes the diagnostic pitfalls. (Source: CytoJournal)
Source: CytoJournal - April 29, 2014 Category: Pathology Authors: Shirish S ChandanwaleCharusheela R GoreSunita A BamanikarNidhi GuptaKanika Gupta Source Type: research
Authors attain comparable or slightly higher rates of citation publishing in an open access journal (CytoJournal) compared to traditional cytopathology journals - A five year (2007-2011) experience
Conclusion : We observed that for the same author, the publications in the OA journal attained a higher rate of citation than the publications in the traditional non-OA journals in the field of cytopathology over a 5 year period (2007-2011). However, this increase was statistically insignificant if the meeting abstracts were excluded from the analysis. Overall, the rates of citation for OA and non-OA were slightly higher to comparable. (Source: CytoJournal)
Source: CytoJournal - April 29, 2014 Category: Pathology Authors: Nora K FrischRomil NathanYasin K AhmedVinod B Shidham Source Type: research
Cytomorphologic spectrum of Hashimoto's thyroiditis and its clinical correlation: A retrospective study of 52 patients
Conclusions: HT is a disease of young and middle age and mostly occur in females. Clinical findings alone may not be adequate for definitive diagnosis. FNA is the gold standard for diagnosis. In the presence of abundant colloid, follicular hyperplasia or co-existing neoplasm, careful interpretation of cytology smears should be done. Aspiration from more than one site minimizes the diagnostic pitfalls. (Source: CytoJournal)
Source: CytoJournal - April 28, 2014 Category: Pathology Authors: Shirish S Chandanwale Charusheela R Gore Sunita A Bamanikar Nidhi Gupta Kanika Gupta Source Type: research
Utility of molecular tests in cytopathology
Arthur David Somoza, F Zahra AlyCytoJournal 2014 11(1):5-5With the popularity of interventional radiology, diagnostic material obtained can be limited requiring critical decisions on making the best use of it. Molecular testing using nanogram amounts of tissue can add useful diagnostic information by improving sensitivity and/or specificity of the diagnosis. This review examines the use of molecular tests in cervical cytology, "indeterminate" thyroid cytology specimens, pancreatic cyst fluid, urinary tract and pulmonary adenocarcinoma cytologic material. Molecular human papillomavirus (HPV) testing combined with ...
Source: CytoJournal - March 20, 2014 Category: Pathology Authors: Arthur David SomozaF Zahra Aly Source Type: research
Thank you CytoJournal reviewers for your 2012 and 2013 services!
Vinod B Shidham, Richard M DeMayCytoJournal 2014 11(1):6-6 (Source: CytoJournal)
Source: CytoJournal - March 20, 2014 Category: Pathology Authors: Vinod B ShidhamRichard M DeMay Source Type: research
The state of cell block variation and satisfaction in the era of molecular diagnostics and personalized medicine
Discussion: Many are dissatisfied with their current method of CB preparation, and there is no consistent method to prepare CBs. In today's era of personalized medicine with an increasing array of molecular tests being applied to cytological specimens, there is a need for a standardized protocol for CB optimization to enhance cellularity. (Source: CytoJournal)
Source: CytoJournal - March 20, 2014 Category: Pathology Authors: John P CrapanzanoJonas J HeymannSara MonacoAziza NassarAnjali Saqi Source Type: research
Cytomorphometric analysis of exfoliated cells in oral lichen planus
Conclusions: The cytomorphometric analysis of OLP shows that erosive/atrophic subtypes of OLP are at more risk and exfoliative cytology and cytomorphometry can be used as a tool to assess the malignant changes. (Source: CytoJournal)
Source: CytoJournal - February 15, 2014 Category: Pathology Authors: Chitturi Suryaprakash Ravi TejaA Santha DevyR Madhavan NirmalPM SunilM Deepasree Source Type: research
Pleural fluid metastases of salivary duct carcinoma: A case report and review of the literature
Julie Huss, Rachel Conrad, Sharon Hirschowitz, Neda MoatamedCytoJournal 2014 11(1):4-4Salivary duct carcinoma (SDC) comprises a small proportion of salivary gland tumors; however, it is known to be aggressive with a high rate of metastasis. Although frequent references are made to pulmonary dissemination, metastases in the pleural fluid have not been described. In this article, we report the cytologic features of metastatic SDC in the pleural fluid. The clinical history, cytomorphology and immunohistochemical features used for diagnosis are described. To the best of our knowledge, this is the first case of pleural fluid in...
Source: CytoJournal - February 15, 2014 Category: Pathology Authors: Julie HussRachel ConradSharon HirschowitzNeda Moatamed Source Type: research
Cytodiagnosis of scar endometriosis
Sandhya Poflee, Anjali Bode, Sonam MahanaCytoJournal 2014 11(1):1-1 (Source: CytoJournal)
Source: CytoJournal - January 31, 2014 Category: Pathology Authors: Sandhya PofleeAnjali BodeSonam Mahana Source Type: research
