Cervical intraepithelial lesions in females attending Women's Health Clinics in Alexandria, Egypt
Conclusion: We concluded that cervical cancer screening programs, although life-saving for a number of women, are not a sufficiently high priority in our community. Money for national health screening programs should preferably be directed more towards recruiting women for breast cancer screening, since breast cancer accounts for about 33% of all female cancers in Egypt ranking number one, while cervical cancer ranks number 13. (Source: CytoJournal)
Source: CytoJournal - June 23, 2015 Category: Pathology Authors: Mona Abdel-HadiAdel KhalafHanaa AboulkassemNoha NaeemMohamed Abdel BaqyHassan Sallam Source Type: research
Survey of cytopathologists and cytotechnologists for the clinical impact of the use of atypia or follicular lesion of undetermined significance
Conclusions: Reporting of the AUS/FLUS category varied widely among different institutions. The median follow-up rate was lower than published guidelines. The most common follow-up diagnosis was benign thyroid nodule. Improved standardization of cytologic criteria should be adopted to reduce such variation. (Source: CytoJournal)
Source: CytoJournal - June 23, 2015 Category: Pathology Authors: Aziza NassarJordan P ReynoldsSarah E KerrSarah M JenkinsKandace A LackoreVictor Bernet Source Type: research
Cervical intraepithelial lesions in females attending Women's Health Clinics in Alexandria, Egypt
Conclusion: We concluded that cervical cancer screening programs, although life-saving for a number of women, are not a sufficiently high priority in our community. Money for national health screening programs should preferably be directed more towards recruiting women for breast cancer screening, since breast cancer accounts for about 33% of all female cancers in Egypt ranking number one, while cervical cancer ranks number 13. (Source: CytoJournal)
Source: CytoJournal - June 22, 2015 Category: Pathology Authors: Mona Abdel-Hadi Adel Khalaf Hanaa Aboulkassem Noha Naeem Mohamed Abdel Baqy Hassan Sallam Source Type: research
Subacute granulomatous (De Quervain's) thyroiditis: Fine-needle aspiration cytology and ultrasonographic characteristics of 21 cases
Conclusion: Though hypoechoic and heterogeneous areas with irregular margins are strongly associated with thyroiditis, SGT may also appear as painful or painless hypoechoic, solid nodules and generate challenges in differential diagnosis. Although the most remarkable characteristic observed in FNA cytology was the presence of multiple MNGCs with cytoplasm, a dirty background accompanied by mild-moderate cellularity, degenerated-proliferated follicular epithelium cells, rare epithelioid granulomas and mixed type inflammatory cells are characteristic for SGT. The assessment of these radiological and cytological findings in c...
Source: CytoJournal - May 21, 2015 Category: Pathology Authors: Çigdem VuralNadir PaksoyNazli D GökKadri Yazal Source Type: research
Thyroid gland and adjacent lesions: Cytomorphological clues!
Amarpreet Bhalla, Linette Meijas-Badillo, Amy Jencks, Vinod B ShidhamCytoJournal 2015 12(1):10-10 (Source: CytoJournal)
Source: CytoJournal - May 21, 2015 Category: Pathology Authors: Amarpreet BhallaLinette Meijas-BadilloAmy JencksVinod B Shidham Source Type: research
Tibial bone metastasis as an initial presentation of endometrial carcinoma diagnosed by fine-needle aspiration cytology: A case report and review of the literature
We report a case of a 77-year-old female with a clinically silent endometrial carcinoma who presented with a left tibial metastasis as the first manifestation of her disease. Ours is only the third case diagnosed by fine-needle aspiration (FNA) cytology, and the first to detail the cytomorphologic features of metastatic endometrial cancer to bone. These microscopic findings, including three-dimensional cohesive clusters with cellular overlapping and cuboidal to columnar cells exhibiting low nuclear: cytoplasmic ratios and partially vacuolated cytoplasm, differ significantly from those of endometrial carcinoma on a Papanico...
Source: CytoJournal - May 21, 2015 Category: Pathology Authors: Sarag Aboujafar BoukharRicky KaneshiroAlan SchillerKeith TeradaPamela Tauchi-Nishi Source Type: research
Subacute granulomatous (De Quervain's) thyroiditis: Fine-needle aspiration cytology and ultrasonographic characteristics of 21 cases
Conclusion: Though hypoechoic and heterogeneous areas with irregular margins are strongly associated with thyroiditis, SGT may also appear as painful or painless hypoechoic, solid nodules and generate challenges in differential diagnosis. Although the most remarkable characteristic observed in FNA cytology was the presence of multiple MNGCs with cytoplasm, a dirty background accompanied by mild-moderate cellularity, degenerated-proliferated follicular epithelium cells, rare epithelioid granulomas and mixed type inflammatory cells are characteristic for SGT. The assessment of these radiological and cytological findings in c...
Source: CytoJournal - May 20, 2015 Category: Pathology Authors: Ç igdem Vural Nadir Paksoy Nazli D G ö k Kadri Yazal Source Type: research
Noninvasive carcinoma ex pleomorphic adenoma of the parotid gland: A difficult diagnosis on fine needle aspiration
Theresa Scognamiglio, Rohan Joshi, William I Kuhel, Sana O Tabbara, M Katayoon Rezaei, Rana S HodaCytoJournal 2015 12(1):7-7Carcinoma ex pleomorphic adenoma (CXPA) is a rare epithelial malignancy that arises from a primary or recurrent pleomorphic adenoma (PA). It may be noninvasive (NI) or invasive. NI CXPA is extremely rare. Preoperative diagnosis on fine needle aspiration (FNA) of CXPA may be difficult and poses a diagnostic challenge to clinicians and pathologists. Herein, we describe the FNA findings of a case of NI-CXPA. A 69-year-old woman presented with rapid enlargement of a stable parotid mass of 25 years. Cytolo...
Source: CytoJournal - April 29, 2015 Category: Pathology Authors: Theresa ScognamiglioRohan JoshiWilliam I KuhelSana O TabbaraM Katayoon RezaeiRana S Hoda Source Type: research
Cytological variations and typical diagnostic features of endocervical adenocarcinoma in situ: A retrospective study of 74 cases
Conclusions: The relatively low diagnostic accuracy AIS was caused by the underestimation of microbiopsies/HCG and the overestimation of polymorphic components. The typical cytological features of AIS are the presence of microbiopsies/HCG with mitotic figures in the absence of necrotic tumor diathesis in specimens containing endocervical samples. The recognition of infrequent AIS subtypes (endometrioid and intestinal subtypes) is also important. (Source: CytoJournal)
Source: CytoJournal - April 29, 2015 Category: Pathology Authors: Takashi UmezawaMiyaka UmemoriAyana HoriguchiKouichi NomuraHiroyuki TakahashiKyosuke YamadaKazunori OchiaiAikou OkamotoMasahiro IkegamiMotoji Sawabe Source Type: research
Cytologic diagnosis of adrenal oncocytic pheochromocytoma in a lung cancer patient: Report of a case and review of the literature
We describe the cytomorphologic findings in our case and provide a review of the reported cases of adrenal oncocytic pheochromocytoma - all of which appear to be benign, nonfunctional, occur in adults, and have similar morphologic features. The pathologist should be aware of this uncommon diagnostic entity and its potential diagnostic pitfalls. (Source: CytoJournal)
Source: CytoJournal - March 25, 2015 Category: Pathology Authors: Anna S NamJune H KoizumiTamar Giorgadze Source Type: research
Detection of pAkt protein in imprint cytology of invasive breast cancer: Correlation with HER2/neu, hormone receptors, and other clinicopathological variables
Conclusions: pAkt expression can be evaluated in cytological material and may add valuable information to current prognostic models for breast cancer. pAkt overexpression appears to be linked with potentially aggressive tumor phenotype in invasive breast carcinoma. (Source: CytoJournal)
Source: CytoJournal - March 25, 2015 Category: Pathology Authors: Olympia VasouLazaros SkagiasMargariti AnastasiaAthanasiadou PaulinaEfstratios PatsourisEkaterini Politi Source Type: research
Pulmonary artery intimal sarcoma diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration
This report describes the cytomorphologic features of this rare intravascular tumor and demonstrates how EBUS-TBNA with ROSE was instrumental in obtaining optimal cytologic sampling for ancillary studies, thus expediting the management. (Source: CytoJournal)
Source: CytoJournal - February 18, 2015 Category: Pathology Authors: Nancy P CarawayDavide SalinaMichael T DeaversRodolfo MoriceGene Landon Source Type: research
Frequency and characterization of celiac ganglia diagnosed on fine-needle aspiration
Conclusions: These data show that celiac ganglia may be infrequently encountered, especially with intra-abdominal EUS-guided FNA targeting nodes or masses near the celiac region. Therefore, cytologists should be aware of the possibility of finding ganglionic cells in EUS-guided FNA samples. (Source: CytoJournal)
Source: CytoJournal - February 18, 2015 Category: Pathology Authors: Ehab A ElGabrySara E MonacoLiron Pantanowitz Source Type: research
Fine-needle aspiration detects primary neuroendocrine carcinoma of the breast in a patient with breast implants
We report a case of a 51-year-old woman with breast implants presenting with an initial diagnosis of fibroadenoma by imaging studies. A definite diagnosis of mammary carcinoma with plasmacytoid cells was made on ultrasound (US)-guided FNAB of the breast mass with rapid on-site evaluation which initiated core needle biopsy of the mass and subsequent mastectomy with sentinel lymph node biopsy. Our case exemplifies the role of US-guided FNAB for the initial investigation of breast masses in patients with implants. In addition, the case illustrates the cytomorphological features of the tumor cells in primary neuroendocrine car...
Source: CytoJournal - January 22, 2015 Category: Pathology Authors: Janet I MalowanyUma KunduLumarie SantiagoSavitri Krishnamurthy Source Type: research
Comparative study of ProEx C immunocytochemistry and UroVysion fluorescent in-situ hybridization assays on urine cytology specimens
Conclusion: ProEx C immunocytochemistry has a more favorable performance than fluorescent in-situ hybridization with a significant difference between the two assays using paired two-tail t-test (P = 0.0033). (Source: CytoJournal)
Source: CytoJournal - January 22, 2015 Category: Pathology Authors: Sue ChangElaine SmithMary LevinJian Yu RaoNeda A Moatamed Source Type: research
