Dual color multiplex TTF-1 + Napsin A and p63 + CK5 immunostaining for subcategorizing of poorly differentiated pulmonary non-small carcinomas into adenocarcinoma and squamous cell carcinoma in fine needle aspiration specimens
Conclusions: Simultaneous coordinate or individual immunostaining for Napsin A / TTF-1 in ADC and p63 / CK5 in SCC demonstrated high sensitivity and specificity. The panel with multiplex Napsin A / TTF-1 and p63 / CK5 dual color immunostains could specifically subcategorize PDC into ADC and SCC in lung FNA specimens. Multiplex dual color Napsin A / TTF-1 and p63 / CK5 immunostaining is especially recommended for evaluation of FNA specimens with relatively scant cellularity. (Source: CytoJournal)
Source: CytoJournal - March 30, 2012 Category: Pathology Authors: Seema Sethi Lili Geng Vinod B Shidham Pamela Archuletta Sudeshna Bandyophadhyay Jining Feng Shashi Madan Dongping Shi Paul Tranchida Tamar Giorgadze Source Type: research

Authors' Reply
Adrienne Carruth Griffin, Lauren Ende Schwartz, Zubair BalochCytoJournal 2012 9(1):3-3 (Source: CytoJournal)
Source: CytoJournal - January 30, 2012 Category: Pathology Authors: Adrienne Carruth Griffin Lauren Ende Schwartz Zubair Baloch Source Type: research

Case study documenting the diagnosis of idiopathic CD4 + Lymphocytopenia in a patient with atypical fungal infection (disseminated blastomycosis) by FNA of adrenal mass
We report a case of a 59-year-old male with ring-enhancing brain lesions, bilateral adrenal masses, lung and vocal cord nodules, where the diagnosis of exclusion was metastatic malignancy. Fine needle aspiration (FNA) of the adrenal mass and a subsequent vocal cord biopsy confirmed chronic widely disseminated blastomycosis. Flow cytometric evaluation of peripheral blood documented persistent selective CD4+ lymphocytopenia with T8 (suppressor) T-Lymphocyte count within normal range. We believe that idiopathic CD4+ lymphocytopenia is an important etiologic factor to be considered for patients who present with m...
Source: CytoJournal - August 4, 2010 Category: Pathology Authors: Richard H Siderits Osman Ouattara Alan Marcus Hong Guang Gao Hong Bing Deng Janusz Godyn Source Type: research

Broom versus broom-and-brush: A comparison of surepath & #174; liquid-based papanicolaou test (LBPT) collection devices
Min Yi Ngae, Clinton D Crowder, Klint Kjeldahl, Roberto Gamez, Samantha Paulson, Daniel M McKeon, Priti Goyal, Stefan E PambuccianCytoJournal 2009 6(1):20-20 (Source: CytoJournal)
Source: CytoJournal - October 8, 2009 Category: Pathology Authors: Min Yi Ngae Clinton D Crowder Klint Kjeldahl Roberto Gamez Samantha Paulson Daniel M McKeon Priti Goyal Stefan E Pambuccian Source Type: research

Does the ThinPrep Imaging System increase the detection of high-risk HPV-positive ASC-US and AGUS ? The Women and Infants Hospital experience with over 200,000 cervical cytology cases
Conclusions: The ASC-US and AGUS rates did not change statistically before and after the introduction of the Imager in our cytology laboratory. Although use of the Imager did not increase detection of HPV+ ASC-US, it did appear to increase the detection rate of HPV+ AGUS and subsequent abnormal biopsy follow-up rates in all categories. However, the increase in the detection rate did not reach the point of statistical significance (Source: CytoJournal)
Source: CytoJournal - August 5, 2009 Category: Pathology Authors: M Ruhul Quddus Theresa Neves Mary E Reilly Margaret M Steinhoff C James Sung Source Type: research

CytoJournal's move to the new platform: More on financial model to the support open-access charter in cytopathology, publication quality indicators, and other issues
Vinod B Shidham, Martha B Pitman, Richard M DeMay, Barbara F AtkinsonCytoJournal 2008 5(1):15-15 (Source: CytoJournal)
Source: CytoJournal - December 15, 2008 Category: Pathology Authors: Vinod B Shidham Martha B Pitman Richard M DeMay Barbara F Atkinson Source Type: research

Myoepithelial Cells : Any role in aspiration cytology smears of breast tumors ?
Conclusion: The number of ME cell in breast lesions may be helpful in distinguishing PBD versus invasive malignant tumors on FNAC smears. However it is not helpful to distinguish benign lesions versus PBD. (Source: CytoJournal)
Source: CytoJournal - April 20, 2008 Category: Pathology Authors: Sanjib Kumar Pattari Pranab Dey Subhash K Gupta Kusum Joshi Source Type: research

Pathologist performed fine needle aspirations & implementation of JCAHO Universal Protocol and " Time out "
This article gives background perspective on the development of the Universal Protocol. It also elaborates the JCAHO National Patients Safety Goals regarding the performance of fine needle aspirations. The compliance with the Universal Protocol for performance of fine needle aspirations is now mandated for all cytopathologists who perform fine needle aspirations and this present paper provides a guideline for fulfilling the requirements of the Universal Protocol for practicing cytopathologists. (Source: CytoJournal)
Source: CytoJournal - September 19, 2007 Category: Pathology Authors: Momin T Siddiqui Source Type: research

Lymphocytic Thyroiditis - is cytological grading significant ? A correlation of grades with clinical, biochemical, ultrasonographic and radionuclide parameters
Conclusion: Despite the availability of several tests for diagnosis of LT, FNAC remains the gold standard. The grades of thyroiditis at cytology however do not correlate with clinical, biochemical, radionuclide and ultrasonographic parameters. (Source: CytoJournal)
Source: CytoJournal - April 29, 2007 Category: Pathology Authors: Alka Bhatia Arvind Rajwanshi Radharaman J Dash Bhagwant R Mittal Akshay K Saxena Source Type: research

Book Review on " Modern Uterine Cytopathology: Moving to the Molecular Smear " by Alexander Meisels MD and Carol Morin, MSc, PhD
Barbara MahoneyCytoJournal 2007 4(1):8-8 (Source: CytoJournal)
Source: CytoJournal - April 12, 2007 Category: Pathology Authors: Barbara Mahoney Source Type: research

Should LSIL with ASC-H (LSIL-H) in cervical smears be an independent category ? A study on SurePath ™ specimens with review of literature
Conclusion: LSIL-H overlapped with LSIL and ASC-H, but was distinct from HSIL. A management algorithm comparable to ASC-H and HSIL appears to be appropriate in LSIL-H cases. (Source: CytoJournal)
Source: CytoJournal - March 19, 2007 Category: Pathology Authors: Vinod B Shidham Nidhi Kumar Raj Narayan Gregory L Brotzman Source Type: research

Introduction of the Thin Prep Imaging System ™ (TIS): Experience in a high volume academic practice
Conclusion :The overall performance of the TIS in our lab appears to be highly satisfactory in terms of improving sensitivity in screening cervical precursor lesions. The increased accuracy of detection of HSIL indicates a positive impact of the TIS in our laboratory. (Source: CytoJournal)
Source: CytoJournal - February 7, 2007 Category: Pathology Authors: Mamatha Chivukula Reda S Saad Esther Elishaev Susan White Nancy Mauser David J Dabbs Source Type: research

Atlas of Salivary Gland Tumor Cytopathology, Oral & Surgical Pathology - CD-ROM Disk 2: by Kini S. & Dardick I. Pathology Images Inc, 2006
Zainab BasirCytoJournal 2006 3(1):26-26This CD-ROM version of Atlas of Salivary Gland Tumor Cytopathology, Oral & Surgical Pathology is an excellent and concise tool for easy reference during sign out of cytology and surgical cases. It is also invaluable as a teaching tool for residents and fellows. Atlas of Salivary Gland Tumor Cytopathology, Oral & Surgical Pathology CD-ROM (ISBN 0-9736518-0-7), Published by Pathology images Inc Ottawa, Ontario K2B 7L4, Canada (Source: CytoJournal)
Source: CytoJournal - November 20, 2006 Category: Pathology Authors: Zainab Basir Source Type: research

First CytoJournal Peer-Reviewer's Retreat in 2006 - Open access, peer-review, and impact factor
Vinod B Shidham, Lynn Sandweiss, Barbara F AtkinsonCytoJournal 2006 3(1):5-5CytoJournal organized its first Peer-Reviewer's Retreat of 2006 during the United States and Canadian Academy of Pathology Annual Meeting at Atlanta on Feb 12, 2006. The major topics discussed were open access, peer review, and impact factors. Representative participants volunteered to join the task force to prepare an instructional guide for peer-reviewing cytopathology manuscripts. Concern about the impact factor for CytoJournal was discussed. A feedback to its readers and authors was recommended. Impact factor calculation needs at least t...
Source: CytoJournal - March 26, 2006 Category: Pathology Authors: Vinod B Shidham Lynn Sandweiss Barbara F Atkinson Source Type: research

Cytologic findings of peripheral T-cell lymphoma (PTCL) with high epitheloid cell content (Lennert's lymphoma) in imprint smear. A case report
Conclusion: Cytologic findings of this variant of lymphoma is distinctive enough for a correct initial suggestive diagnosis. However the presence of high content of epitheloid cell clusters can cause cytologic misinterpretation with other benign and malignant conditions. (Source: CytoJournal)
Source: CytoJournal - February 5, 2006 Category: Pathology Authors: Yahya Daneshbod Source Type: research