Cytopathology of neoplastic meningitis: A series of 66 cases from a tertiary care center
Conclusion: CSF cytology is an important tool for diagnosis of NM. Cytomorphologic features helped in diagnosis and for prediction of the primary site. Correct identification of this condition is important as it has therapeutic and prognostic implications. (Source: CytoJournal)
Source: CytoJournal - June 29, 2013 Category: Pathology Authors: Gurdeep SinghSandeep R MathurVK IyerDeepali Jain Source Type: research
Gallbladder carcinoma: An attempt of WHO histological classification on fine needle aspiration material
Conclusions: US guided FNAC is a safe and effective method to diagnose CaGB. Although, rare, clinically and prognostically significant variants described in WHO classification can be detected on cytology. (Source: CytoJournal)
Source: CytoJournal - June 18, 2013 Category: Pathology Authors: Rajni YadavDeepali JainSandeep R MathurAtul SharmaVenkateswaran K Iyer Source Type: research
Performance of endoscopic ultrasound-guided fine needle aspiration in diagnosing pancreatic neuroendocrine tumors
Conclusions: Our data demonstrated that EUS-FNA has a relatively high sensitivity for diagnosing PNETs. Lack of additional materials for immunocytochemical studies could lead to a less definite diagnosis. Non-diagnostic or false negative FNA diagnosis can be seen in a limited number of cases, especially in those small sized tumors. (Source: CytoJournal)
Source: CytoJournal - May 29, 2013 Category: Pathology Authors: Jane BernsteinBerrin UstunAhmed AlomariFang BaoHarry R AslanianUzma SiddiquiDavid ChhiengGuoping Cai Source Type: research
Cytodiagnosis of gouty tophus
Vaishali Walke, Sushma Ramraje, Vinod JadhaoCytoJournal 2013 10(1):11-11 (Source: CytoJournal)
Source: CytoJournal - May 29, 2013 Category: Pathology Authors: Vaishali WalkeSushma RamrajeVinod Jadhao Source Type: research
Metastatic colorectal adenocarcinoma in cervicovaginal cytology specimens confirmed by immunocytochemical stains on liquid base specimens: Two study cases with review of the literature
We present two cases of metastatic colorectal ACA diagnosed on cervicovaginal ThinPrep (TP) Pap smears, with one confirmed by ICC staining method. Recognition of extra-uterine malignancy in the cervicovaginal cytology specimen is critical for the disease diagnosis, prognosis, and the treatment. ICC staining performed on the residual LBC specimen is an important methodology to confirm the diagnosis. (Source: CytoJournal)
Source: CytoJournal - May 20, 2013 Category: Pathology Authors: Muhammad ZulfiqarSusan LiuDongping ShiShashi MadanSuzanne JacquesLaquita KingVinod ShidhamTamar Giorgadze Source Type: research
Cytomorphology of Boerhaave's syndrome: A critical value in cytology
We describe a case of an 81-year-old female with esophageal perforation who presented with a left sided pleural effusion. The correct diagnosis was established in this case by observing gastrointestinal-like fluid characteristics of the thoracic drainage upon cytological and chemical analyses and the rupture was confirmed by esophagography. The cytological examination of pleural fluid revealed benign reactive squamous cells, fungal organisms, bacterial colonies, and vegetable material consistent with a ruptured esophagus. Cytological examination of pleural fluid is a rapid and accurate technique that can help in establishi...
Source: CytoJournal - April 30, 2013 Category: Pathology Authors: Walid E KhalbussShveta HoodaManon Auger Source Type: research
Cytomorphology of Boerhaave's syndrome: A critical value in cytology
We describe a case of an 81-year-old female with esophageal perforation who presented with a left sided pleural effusion. The correct diagnosis was established in this case by observing gastrointestinal-like fluid characteristics of the thoracic drainage upon cytological and chemical analyses and the rupture was confirmed by esophagography. The cytological examination of pleural fluid revealed benign reactive squamous cells, fungal organisms, bacterial colonies, and vegetable material consistent with a ruptured esophagus. Cytological examination of pleural fluid is a rapid and accurate technique that can help in establishi...
Source: CytoJournal - April 29, 2013 Category: Pathology Authors: Walid E Khalbuss Shveta Hooda Manon Auger Source Type: research
Abdominopelvic washings: A comprehensive review
This article provides a comprehensive and contemporary review of abdominopelvic washings in the evaluation of gynecologic and non-gynecologic tumors, including primary peritoneal and mesothelial entities. (Source: CytoJournal)
Source: CytoJournal - April 24, 2013 Category: Pathology Authors: Erika F RodriguezSara E MonacoWalid KhalbussR Marshall AustinLiron Pantanowtiz Source Type: research
Effect of Thin Prep® imaging system on laboratory rate and relative sensitivity of atypical squamous cells, high-grade squamous intraepithelial lesion not excluded and high-grade squamous intraepithelial lesion interpretations
Conclusion: The similar rate of detection using TIS with an equal percentage of histologic correlation for ASC-H and HGSIL lesions on follow-up histology suggests patients screened by the TIS method are being sent for appropriate follow-up surveillance and treatment. A high-grade or possible high-grade lesion is as likely to be detected by TIS as by a manual screen. The similarities in relative sensitivity and specificity in a direct comparison between manual and TIS screening methodologies indicate that TIS compared to manual screening does not affect detection in patients with high-grade cervical lesions. (Source: CytoJournal)
Source: CytoJournal - March 30, 2013 Category: Pathology Authors: Brooke R KoltzDonna K RussellNaiji LuThomas A BonfiglioSharlin Varghese Source Type: research
Effect of Thin Prep & #174; imaging system on laboratory rate and relative sensitivity of atypical squamous cells, high-grade squamous intraepithelial lesion not excluded and high-grade squamous intraepithelial lesion interpretations
Conclusion: The similar rate of detection using TIS with an equal percentage of histologic correlation for ASC-H and HGSIL lesions on follow-up histology suggests patients screened by the TIS method are being sent for appropriate follow-up surveillance and treatment. A high-grade or possible high-grade lesion is as likely to be detected by TIS as by a manual screen. The similarities in relative sensitivity and specificity in a direct comparison between manual and TIS screening methodologies indicate that TIS compared to manual screening does not affect detection in patients with high-grade cervical lesions. (Source: CytoJournal)
Source: CytoJournal - March 29, 2013 Category: Pathology Authors: Brooke R Koltz Donna K Russell Naiji Lu Thomas A Bonfiglio Sharlin Varghese Source Type: research
Fine needle aspiration cytology in diagnosis of salivary gland lesions: A study with histologic comparison
Conclusion: FNAC continues to be a reliable diagnostic technique in hands of an experienced cytopathologist. The sensitivity of diagnosis of malignant lesions is high, though the rate of tumor type-specific characterization is lower, due to variable cytomorphology. In difficult cases, histologic examination may be employed for accurate diagnosis. (Source: CytoJournal)
Source: CytoJournal - March 25, 2013 Category: Pathology Authors: Ritu JainRuchika GuptaMadhur KudesiaSompal Singh Source Type: research
Constructing a modern cytology laboratory: A toolkit for planning and design
Conclusions: Lab construction should be a systematic process based on sound principles for safety, high quality testing, and finance. Our detailed planning and design process can be a model for others undertaking similar projects (Source: CytoJournal)
Source: CytoJournal - February 28, 2013 Category: Pathology Authors: Janie RobersonAllison WrennJohn PooleAndrew JaegerIsam A Eltoum Source Type: research
Micropapillary urothelial carcinoma: Cytologic features in a retrospective series of urine specimens
Conclusions and Summary : Further investigation of the core cytopathological characteristics of uPC is warranted to refine its diagnostic criteria by exfoliative urine cytology. (Source: CytoJournal)
Source: CytoJournal - February 28, 2013 Category: Pathology Authors: Jonas John HeymannAnjali SaqiAndrew Thomas TurkJohn Crapanzano Source Type: research
Metastatic urachal carcinoma in bronchial brush cytology
We present a case of metastatic urachal adenocarcinoma in bronchial brushings and review the use of immunohistochemistry in its diagnosis. A 47-year-old female was seen initially in 2007 with adenocarcinoma of the bladder dome for which she underwent partial cystectomy. She presented in 2011 with a left lung mass and mediastinal adenopathy. Bronchoscopy showed an endobronchial lesion from which brushings were obtained. These showed numerous groups of columnar cells with medium sized nuclei and abundant cytoplasm. The cells were positive for CK20 and CDX2 and negative for CK7. The cytomorphological findings were similar to ...
Source: CytoJournal - January 31, 2013 Category: Pathology Authors: Fatima Zahra AlyAbeer Z TabbarahLysandra Voltaggio Source Type: research
Oncocytic follicular nodules of the thyroid with or without chronic lymphocytic thyroiditis: An institutional experience
Conclusions: Based on this study, nodule size and not CLT appears to be an important clinicopathologic features in the management of thyroid FNA specimens diagnosed as OFN. (Source: CytoJournal)
Source: CytoJournal - January 31, 2013 Category: Pathology Authors: Sule CanberkA Carruth GriffinAbha GoyalHe WangKathleen MontoneVirginia LiVolsiZubair Baloch Source Type: research
