Growth of Axons
The recently elucidated molecular structure of neuronal axons is based on a tubular sequence of adducin-capped actin rings connected by spectrin tetramers. It has been suggested that this structure is formed by supramolecular polymerization of repeating unimers based on spectrin tetramers bound to actin rings. The large number of spectrin molecules connected to each actin ring enormously increases the rigidity of the assembly and the degree of polymerization. During axonal growth, new unimers can dynamically polymerize and macroscopic dimensions are attained. Fundamental self-assembly mechanisms assist the growth of neuron...
Source: Current Chemical Biology - November 25, 2016 Category: Biochemistry Source Type: research
Meet Our Associate Editor
(Source: Current Chemical Biology)
Source: Current Chemical Biology - November 25, 2016 Category: Biochemistry Source Type: research
"Take and Run" and "Take and Hold" Therapeutical Electromagnetic Field Application Modalities in Physiotherapy: Some Clinically Significant Pathways of Action
This paper proposes and for the first time examines in parallel the most likely mechanisms of clinical effects unlocked by two modality applications: the therapeutic (acute) “take and run” and the occupational (chronic) “take and hold” of therapeutic EMFs. Electromagnetic fields (EMFs) for therapeutic use have a long pre-clinical and clinical history. The practical experience worldwide has increased the trust of the medical community due to the EMF potential for speeding up the recovery and reparative processes and for influencing the pathological ones – edema, pain, inflammation. We consider these favourable eff...
Source: Current Chemical Biology - July 21, 2016 Category: Biochemistry Source Type: research
Editorial (Thematic Issue: “Effects of Man-Made Electromagnetic Fields on Simple Organic Systems and Cellular Functions”)
(Source: Current Chemical Biology)
Source: Current Chemical Biology - July 21, 2016 Category: Biochemistry Source Type: research
Influence of Pulsing Electromagnetic Field Therapy on Gene Expression in Muscle Cells, Peripheral Circulation, and Metabolic Factors in Aging Adults
This study tested the acute effects of pulsating electromagnetic field (PEMF) therapy session on gene expression in muscle cells, and the changes in cardiovascular and metabolic function in a group of older adults after 12 weeks of treatment. Each therapy session involved 15 minutes of exposure to low frequency pulsating asymmetrical waveforms emitted by the Impulser™ Pro mattress. The treatment was provided five days per week for a total of 60 sessions. Pre and post session muscle biopsies provided tissue for analyses of selected genes. Blood pressure and arterial stiffness was determined for cardiovascular function whi...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
Electromagnetic Fields Act Similarly in Plants as in Animals: Probable Activation of Calcium Channels via Their Voltage Sensor
It has been shown that low intensity microwave/lower frequency electromagnetic fields (EMFs) act in animals via activation of voltage-gated calcium channels (VGCCs) in the plasma membrane, producing excessive intracellular calcium [Ca2+]i, with excessive [Ca2+]i leading to both pathophysiological and also in some cases therapeutic effects. The pathophysiological effects are produced largely through excessive [Ca2+]i signaling including excessive nitric oxide (NO), superoxide, peroxynitrite, free radical formation and consequent oxidative stress. The activation of the VGCCs is thought to be produced via EMF impact on the VG...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
Effects of Wi-Fi Radiation on Germination and Growth of Broccoli, Pea, Red Clover and Garden Cress Seedlings: A Partial Replication Study
Background: This is a partial replication study of work conducted by high school students in Denmark as part of their science fair project. Objective: The purpose of this study is to determine whether radiation from a Wi-Fi router affects germination and growth of garden cress (Lepidium sativum), broccoli (Brassica oleracea), red clover (Trifolium pratense) and pea (Pisum sativum). Method: One set of seeds was placed in Petri plates in a germination chamber kept under controlled conditions and was exposed to microwave radiation generated by a Wi-Fi router (mean and maximum exposures 20–40 and 96 mW/m2 respectively). The ...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
The Shielding Action of Disaccharides for Typical Proteins in Aqueous Solution Against Static, 50 Hz and 1800 MHz Frequencies Electromagnetic Fields
The present review paper deals with experimental findings on the shielding action effects of two homologous disaccharides, i.e. sucrose and trehalose, against applied electromagnetic fields. The study, performed by means of the Fourier Transform InfraRed technique, is addressed to examine the effects of electromagnetic fields exposure on the secondary structure of some prototypal proteins (haemoglobin, bovine serum albumin and lysozyme) in aqueous solution, both in the absence and presence of the disaccharides. More specifically, haemoglobin and bovine serum albumin water solutions, in the absence and presence of sucrose...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
"Take and Run" and "Take and Hold" Therapeutical Electromagnetic Field Application Modalities in Physiotherapy: Some Clinically Significant Pathways of Action
This paper proposes and for the first time examines in parallel the most likely mechanisms of clinical effects unlocked by two modality applications: the therapeutic (acute) “take and run” and the occupational (chronic) “take and hold” of therapeutic EMFs. Electromagnetic fields (EMFs) for therapeutic use have a long pre-clinical and clinical history. The practical experience worldwide has increased the trust of the medical community due to the EMF potential for speeding up the recovery and reparative processes and for influencing the pathological ones – edema, pain, inflammation. We consider these favourable eff...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
Early Development of Sea Urchin P.lividus Under Static (6 mT) and Pulsed Magnetic Fields (15 and 72 Hz)
The effects of exposure to 6 mT Static Magnetic Field (SMF) and to 15 and 72 Hz Pulsed ElectroMagnetic Fields (PEMFs) on the early development of the sea urchin P.lividus were evaluated. The amplitudes of PEMFs were chosen in the range of that approved for magnetotherapy and the magnetic induction of SMF was the one already shown to interfere with some cell functions in in vitro experiments. P.lividus embryos, from fertilization to pluteus larva (about 72 h of development) were exposed to the different MFs continuously or alternating periods under MFs exposure with periods without exposure. The type of applied MF (static o...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
Effect of Non-Ionizing Electromagnetic Fields of Anthropic Origin on Male Fertility
In conclusion, a further great research effort would be needed to clarify this controversial and important topic. (Source: Current Chemical Biology)
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
Bio Energy Man Produced Technique to Control the EMF of the Mitochondria in Order to Re Establish Cell´s Normal Functions
The importance of H1 in metabolic energy driving reactions due to its reductive power, seems to be a necessary cofactor and driving force in different metabolic processes, such as oxidative phosphorylation in the carcinogenic cell. Normal cells requires a production of a higher level of ATP (in energy way) to attain the transformation between neoplastic and normal differentiated cell, in order to sustain all the mechanisms required by the body to produce, in adequate levels, enough energy to ignite at that point, the production of amino acids and enzymes that are precursors of different types of neurotransmitters and hormo...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
The Effect of Non-Thermal Microwave-Treated Physiological Solution on Isolated Heart Muscle of Snail
The effects of non-thermal intensity of microwave (NT MW)- treated physiological solutions (PS) on muscle contractility, 45Ca uptake by muscle and muscle hydration of snail isolated heart in normal and K+-free PS were studied. The intra-cordial perfusion by NT MW-treated PS led to inhibition of heart beating with gradual decrease of the amplitudes of muscle contraction, the weakness of the Na+/K+ pump-induced transient inhibition of heart beating (TIHB), the inhibition of 45Ca2+ uptake by muscle, the increase of intracellular cGMP contents and muscle dehydration. The obtained data serve as additional evidence for hypothesi...
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
EDITORIAL: “Effects of Man-Made Electromagnetic Fields on Simple Organic Systems and Cellular Functions”
(Source: Current Chemical Biology)
Source: Current Chemical Biology - July 20, 2016 Category: Biochemistry Source Type: research
Acknowledgements to Reviewers:
(Source: Current Chemical Biology)
Source: Current Chemical Biology - March 11, 2016 Category: Biochemistry Source Type: research
