Zebrafish miR-462-731 is required for digestive organs development
Publication date: Available online 29 February 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Yan Huang, Chun-Xiao Huang, Wei-Feng Wang, Hong Liu, Huan-Ling Wang (Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics)
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - March 1, 2020 Category: Genetics & Stem Cells Source Type: research

Impact of polyethylene on salivary glands proteome in Galleria melonella
Publication date: Available online 24 February 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Asal Peydaei, Hedayat Bagheri, Leonid Gurevich, Nadieh de Jonge, Jeppe Lund Nielsen (Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics)
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 26, 2020 Category: Genetics & Stem Cells Source Type: research

Transcriptome analysis of Liriomyza trifolii (Diptera: Agromyzidae) in response to temperature stress
Publication date: Available online 24 February 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Ya-Wen Chang, Xiao-Xiang Zhang, Ming-Xing Lu, Wei-Rong Gong, Yu-Zhou Du (Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics)
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 26, 2020 Category: Genetics & Stem Cells Source Type: research

Deiminated proteins and extracellular vesicles - novel serum biomarkers in whales and Orca
Publication date: Available online 20 February 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Bergljot Magnadottir, Pinar Uysal-Onganer, Igor Kraev, Vilhjalmur Svansson, Polly Hayes, Sigrun LangeAbstractPeptidylarginine deiminases (PADs) are a family of phylogenetically conserved calcium-dependent enzymes which cause post-translational protein deimination. This can result in neoepitope generation, affect gene regulation and allow for protein moonlighting via functional and structural changes in target proteins. Extracellular vesicles (EVs) carry cargo proteins and genetic mate...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 20, 2020 Category: Genetics & Stem Cells Source Type: research

Transcriptome analysis of phototransduction-related genes in tentacles of the sea cucumber Apostichopus japonicus
In this study, we performed RNA-Seq analysis to examine the tentacle transcriptome of A. japonicus specimens that had been subjected to dark and light (5 min and 1 h) conditions. We specifically focused on detecting genes involved in opsin-based light perception, including opsins and members of phototransduction-related pathways. On the basis of comparisons with both vertebrate and invertebrate phototransduction pathways, we determined that components of two of the main metazoan phototransduction pathways were altered in response to illumination. Among the key phototransduction-related genes in tentacles, we identified...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 19, 2020 Category: Genetics & Stem Cells Source Type: research

Analysis of testis metabolome and transcriptome from the oriental river prawn (Macrobrachium nipponense) in response to different temperatures and illumination times
Publication date: Available online 13 February 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Shubo Jin, Yuning Hu, Hongtuo Fu, Shengming Sun, Sufei Jiang, Yiwei Xiong, Hui Qiao, Wenyi Zhang, Yongsheng Gong, Yan WuAbstractA better understanding of the mechanisms underlying the male sexual differentiation of Macrobrachium nipponense is urgently needed in order to maintain sustainable development of the M. nipponense industry. Environmental factors, especially temperature and illumination, have dramatic effects on gonadal development. The aim of the present study was to identify...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 13, 2020 Category: Genetics & Stem Cells Source Type: research

Editorial Board
Publication date: March 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, Volume 33Author(s): (Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics)
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 12, 2020 Category: Genetics & Stem Cells Source Type: research

In Appreciation
Publication date: March 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, Volume 33Author(s): (Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics)
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 12, 2020 Category: Genetics & Stem Cells Source Type: research

Effects of bacterial haemorrhagic septicemia on the immune response of Leiocassis longirostris by RNA-Seq and microRNA-Seq
In this study, a total of 92.16 and 95.61 million (M) high-quality transcriptome reads were generated from the control group (CG) and experimental group (EG) spleen samples, respectively, and 207 up-regulated and 185 down-regulated genes were identified. These genes were enriched in 29 GO terms and 30 KEGG pathways (P ≤ 0.05), including cytokine-cytokine receptor interaction and complement and coagulation cascades, with 17 up-regulated genes and 12 down-regulated genes related to immune responses in the EG relative to the CG. Based on the zebrafish genome, miRNA-seq identified a total of 343 miRNAs, of which 15 were ...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 10, 2020 Category: Genetics & Stem Cells Source Type: research

Acute air exposure modulates the microRNA abundance in stress responsive tissues and circulating extracellular vesicles in rainbow trout (Oncorhynchus mykiss)
In this study, adult rainbow trout were exposed to a 3-minute acute air stress and allowed to recover for 1-, 3-, or 24-h to determine how miRNAs were altered. MicroRNAs measured in this study were chosen based on their high relative abundance in tissues that drive the stress response (miR-21a-3p, let-7a-5p, miR-143-3p) or their role in regulating DNA methylation (miR-29a-3p). In general, miRNAs increased in circulating EVs during the recovery period while decreasing in head kidney and liver at the same timepoints. Predicted targets for these miRNAs were analyzed using KEGG and DAVID functional enrichment analysis. Pathway...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 5, 2020 Category: Genetics & Stem Cells Source Type: research

Protein lysine methylation in the regulation of anoxia tolerance in the red eared slider turtle, Trachemys scripta elegans
Publication date: Available online 1 February 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Kyle K. BiggarAbstractThe red eared slider turtle (Trachemys scripta elegans) is a champion vertebrate facultative anaerobe, capable of surviving for several months under conditions of exceptionally low oxygen availability. The ability of the turtle to facilitate this impressive tolerance to oxygen restriction is accomplished through a dramatic reduction in non-essential cellular processes. This is done in an attempt to conserve limited ATP stores and match demand in the anoxic state, ...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - February 1, 2020 Category: Genetics & Stem Cells Source Type: research

Identification and sex-biased profiles of candidate olfactory genes in the antennal transcriptome of the parasitoid wasp Cotesia vestalis
Publication date: Available online 29 January 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): Yipeng Liu, Lixiao Du, Yun Zhu, Shiyong Yang, Qiong Zhou, Guirong Wang, Yang LiuAbstractCotesia vestalis (Hymenoptera: Braconidae) is an endoparasitoid wasp that attacks larvae of the diamondback moth, Plutella xylostella (Linnaeus), one of the most important pests of cruciferous plants in the world. This natural enemy has been used to control populations of P. xylostella. To more fully understand the molecular mechanisms of olfactory reception in C. vestalis, the transcriptomes of mal...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - January 30, 2020 Category: Genetics & Stem Cells Source Type: research

Shotgun proteomics analysis reveals sub-lethal effects in Daphnia magna exposed to cell-bound microcystins produced by Microcystis aeruginosa
This study examines the effects of cell-bound microcystin exposure in Daphnia magna as a function of dose and time with shotgun proteomics in order to measure and provide insightful evidence describing functional mechanisms from, and relationships between, protein populations in response to toxic Microcystis aeruginosa. We further characterize the life-history fitness of D. magna in the presence of toxic exposure by measuring somatic growth rate. Chronic dietary exposure to cell-bound microcystins reduced the somatic growth rate of D. magna. Through proteomics analysis, we identified a significant increase in abundance of ...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - January 30, 2020 Category: Genetics & Stem Cells Source Type: research

Characterizing physical protein targets of chemical contaminants with chemical proteomics: Is it time to fill a crucial environmental toxicology knowledge gap?
Publication date: Available online 29 January 2020Source: Comparative Biochemistry and Physiology Part D: Genomics and ProteomicsAuthor(s): David Ross Hall, Hui PengAbstractCurrent environmental toxicological studies are challenged by the immense number (>80,000) of chemical contaminants. While several strategies including adverse outcome pathway (AOP), High-Throughput Screening (HTS), and computational toxicology have been proposed to tackle this challenge, we argue here that characterizing the protein targets of chemical contaminants is the major bottleneck. In this commentary article, we reviewed current environmental t...
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - January 30, 2020 Category: Genetics & Stem Cells Source Type: research

Comparative metabolomics analysis of ovarian developmental stages in Macrobrachium nipponense
This study provides a systematic and comprehensive metabolomics analysis of ovarian development in M. nipponense and lays a foundation for addressing the problem of rapid sexual maturity.Graphical abstract (Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics)
Source: Comparative Biochemistry and Physiology Part D: Genomics and Proteomics - January 30, 2020 Category: Genetics & Stem Cells Source Type: research