Cold atmospheric pressure plasma jet modulates Candida albicans virulence traits
In conclusion, He-CAPPJ was able to attenuate fungal adherence and morphogenesis with low cytotoxicity after short treatment times. Periods of exposure effective against biofilms were cytotoxic to Vero cells. He-CAPPJ did not show genotoxic effect. Therefore, He-CAPPJ has potential to be applied as an adjuvant in the treatment of C. albicans superficial infections. (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - August 15, 2017 Category: Research Source Type: research

Effect of N2/O2 composition on inactivation efficiency of Escherichia coli by discharge plasma at the gas-solution interface
Publication date: December 2017 Source:Clinical Plasma Medicine, Volumes 7–8 Author(s): Zhigang Ke, Prutchayawoot Thopan, Greg Fridman, Vandana Miller, Liangdeng Yu, Alexander Fridman, Qing Huang Bacterial inactivation by discharge plasma is affected by many factors including gas type. No uniform conclusion for the effect of working gas type on the inactivation efficiency has been reached until now. In this work, the gas type and composition (O2, N2 and air) on the inactivation efficiency of Escherichia coli by corona discharge plasma at the gas-solution interface produced using needle high-voltage electrode abo...
Source: Clinical Plasma Medicine - August 15, 2017 Category: Research Source Type: research

Evaluation the Effectiveness of Combinative Treatment of Cold Plasma Jet, Indonesian Honey, and Micro-Well Dressing to Accelerate Wound Healing
Publication date: Available online 7 March 2017 Source:Clinical Plasma Medicine Author(s): Nasruddin, Indri Kartika Putri, Sodiq Kamal, Heni Setyowati Esti Rahayu, Heni Lutfiyati, Prasojo Pribadi, Tiara Mega Kusuma, Zaenul Muhlisin, Muhammad Nur, Laela Hayu Nurani, Budi Santosa, Tatsuo Ishijima, Toshio Nakatani A combinative treatment of cold plasma jet, honey solution, and micro-well dressing to accelerate acute wound healing of mouse skin was evaluated. A honey solution 1% in phosphate-buffered saline (PBS) 20µL was dropped into micro-well dressing that is attached on an acute wound before a 2-minute cold...
Source: Clinical Plasma Medicine - March 6, 2017 Category: Research Source Type: research

Bonding to Zirconia Ceramic: The Effect of Cold Plasma Treatment and 4-META
Conclusions While adhesive monomers demonstrated significant increases of SBS, plasma treatment showed inconsistent results. Pretreatment measures may be crucial for the success of bonding procedures and only validated procedures should be applied in the clinical routine. (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - January 4, 2017 Category: Research Source Type: research

Corrigendum to ‘Bactericidal efficacy of cold plasma in processed bone. A new approach for adjuvant therapy of medication-related osteonecrosis of the jaw?’ [Clin. Plasma Med. 4(1) (2016) 9–13]
Publication date: Available online 26 December 2016 Source:Clinical Plasma Medicine Author(s): Shady Abu-Sirhan, Moritz Hertel, Saskia Preissner, Henrik Carl Wirtz, Sascha Rudolf Herbst, Philipp Pierdzioch, Jan-Dirk Raguse, Stefan Hartwig (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - December 25, 2016 Category: Research Source Type: research

In vitro killing of mycobacteria by low temperature atmospheric pressure plasma and dielectric barrier discharge plasma for treatment of tuberculosis
Conclusion Plasma treatment (both sources) may serve as a future option for treatment of skin tuberculosis evolved from M. tuberculosis (lupus vulgaris), NTM and leprosy and also for surface decontamination after suspected contact with acid fast microbes. (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - November 25, 2016 Category: Research Source Type: research

Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma Source Construction and Investigation on the Effect of Grid on Wound Healing Application
Publication date: Available online 13 November 2016 Source:Clinical Plasma Medicine Author(s): Zahra Shahbazi Rad, Fereydoun Abbasi Davani Non-thermal atmospheric pressure plasma sources are already known as an attractive devices for therapeutic applications including wound healing. The purpose of this investigation was to construct a portable device for skin wound healing. A planar atmospheric pressure Dielectric Barrier Discharge (DBD) plasma device was constructed. The effect of using mesh grid with DBD device was investigated for uniformity treatment of skin wounds. Reactive Nitrogen and Oxygen species were observe...
Source: Clinical Plasma Medicine - November 13, 2016 Category: Research Source Type: research

Non-thermal plasma enhanced bonding of resin cement to zirconia ceramic
Publication date: Available online 27 August 2016 Source:Clinical Plasma Medicine Author(s): Tianshuang Liu, Liang Hong, Timothy Hottel, Xiaoqing Dong, Qingsong Yu, Meng Chen (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - August 27, 2016 Category: Research Source Type: research

First Insights on Plasma Orthodontics - Application of Cold Atmospheric Pressure Plasma to enhance the bond strength of orthodontic brackets
Conclusions Despite promising potential, surface conditioning with CAP could not improve the adhesive properties of GIC. By contrast, a decrease in shear bond strength was noticed after CAP treatment. Further investigations have to show whether it is possible to increase the retention values ​​of other orthodontic adhesives by CAP application and thus take advantage of positive characteristics and reduce side effects. (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - August 5, 2016 Category: Research Source Type: research

Research on plasma medicine-relevant plasma –liquid interaction: What happened in the past five years?
Publication date: December 2015 Source:Clinical Plasma Medicine, Volume 3, Issue 2 Author(s): Helena Jablonowski, Thomas von Woedtke During the last five years mechanisms of plasma-induced change of liquid chemistry have drawn huge attention in basic research in plasma medicine because liquid phase processes have been identified to be the main key to understand detailed mechanisms of atmospheric pressure plasma effects on living systems. Moreover, plasma-activated liquids are considered to be useful for several applications also in the medical field. This review gives a compilation of the work done in the past five...
Source: Clinical Plasma Medicine - July 20, 2016 Category: Research Source Type: research

Introduction to DIN-specification 91315 based on the characterization of the plasma jet kINPen ® MED
Publication date: December 2016 Source:Clinical Plasma Medicine, Volume 4, Issue 2 Author(s): Miriam Stella Mann, Regina Tiede, Karsten Gavenis, Georg Daeschlein, Rene Bussiahn, Klaus-Dieter Weltmann, Steffen Emmert, Thomas von Woedtke, Raees Ahmed Standardization is an important tool to reduce costs and risks of research. For the innovative field of plasma medicine, no national or international standards could be identified until now. The present study introduces the first German DIN (German Institute of Standardization)-specification 91315 named “General requirements for medical plasma sources” ...
Source: Clinical Plasma Medicine - July 20, 2016 Category: Research Source Type: research

Introduction to DIN-Specification 91315 based on the characterization of the plasma jet kINPen® MED
Publication date: Available online 17 June 2016 Source:Clinical Plasma Medicine Author(s): Miriam Stella Mann, Regina Tiede, Karsten Gavenis, Georg Daeschlein, Rene Bussiahn, Klaus-Dieter Weltmann, Steffen Emmert, Thomas von Woedtke, Raees Ahmed Standardization is an important tool to reduce costs and risks of research. For the innovative field of plasma medicine, no national or international standards could be identified until now. The present study introduces the first German DIN (German Institute of Standardization)-specification 91315 named “General requirements for medical plasma sources” whi...
Source: Clinical Plasma Medicine - June 16, 2016 Category: Research Source Type: research

The application of cold atmospheric plasma in medicine: The potential role of nitric oxide in plasma-induced effects
Publication date: Available online 12 May 2016 Source:Clinical Plasma Medicine Author(s): Christoph V. Suschek, Christian Opländer The use of non-thermal atmospheric pressure plasma (CAP) in medicine is promising and presents a new approach in the treatment of chronic wounds and skin infections. Many CAPs contain considerable amounts of nitric oxide (NO) and nitrogen dioxide (NO2), which induce acidification and nitrite/nitrate accumulation in treated tissues/liquids. Since many pathological conditions, such as impaired wound healing and microcirculation, are often related to restricted NO bioavailability, CAP sou...
Source: Clinical Plasma Medicine - May 11, 2016 Category: Research Source Type: research

Improving bond strength of ground and intact enamel to mild self-etch adhesive by plasma treatment
This study provides the prospect of replacing the traditional selective etching step using a simple non-thermal plasma treatment technique. (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - March 21, 2016 Category: Research Source Type: research

The Plasma Jet kINPen – A Powerful Tool for Wound Healing
Publication date: Available online 22 January 2016 Source:Clinical Plasma Medicine Author(s): Sander Bekeschus, Anke Schmidt, Klaus-Dieter Weltmann, Thomas von Woedtke The development of cold atmospheric pressure plasma sources was the starting point for the innovative field of plasma medicine many years ago. Today, a large body of information is available on the biomedical and clinical applications of plasma. Among the latter, wound healing is of special interest as there have been promising studies demonstrating a benefit of plasma in the treatment of chronic wounds. Wound healing is tightly regulated by redo...
Source: Clinical Plasma Medicine - January 22, 2016 Category: Research Source Type: research