Possible therapeutic option of aqueous plasma for refractory ovarian cancer
Publication date: Available online 22 December 2015 Source:Clinical Plasma Medicine Author(s): Hiroaki Kajiyama, Fumi Utsumi, Kae Nakamura, Hiromasa Tanaka, Masaaki Mizuno, Shinya Toyokuni, Masaru Hori, Fumitaka Kikkawa Based on a number of recent reports, plasma exerts anti-proliferative and apoptotic effects on various cancer cells. Besides a direct effect on the cells, the proliferation of normal and tumorous mammalian cells was reported to be downregulated by indirect plasma-exposed medium through the generation of reactive oxidative species. We demonstrated that plasma-activated medium (PAM) also h...
Source: Clinical Plasma Medicine - December 22, 2015 Category: Research Source Type: research
Chemical analysis of reactive species and antimicrobial activity of water treated by nanosecond pulsed DBD air plasma
Publication date: Available online 31 October 2015 Source:Clinical Plasma Medicine Author(s): R. Laurita, D. Barbieri, M. Gherardi, V. Colombo, P. Lukes Deionized water, phosphate buffer and dilute electrolyte solution from sodium dihydrogenphosphate were treated by nanosecond pulsed DBD air plasma. Hydrogen peroxide, nitrates and nitrites produced by plasma treatment were measured by means of both quantitative and semi-quantitative methods. Phenol was used as chemical probe for ROS and RNS. Post-discharge kinetic of phenol degradation gave evidence of the formation of peroxynitrite by H+-catalyzed reaction o...
Source: Clinical Plasma Medicine - December 14, 2015 Category: Research Source Type: research
Preliminary investigation of the antibacterial efficacy of a handheld Plasma Gun source for endodontic procedures
Publication date: Available online 11 November 2015 Source:Clinical Plasma Medicine Author(s): E. Simoncelli, D. Barbieri, R. Laurita, A. Liguori, A. Stancampiano, L. Viola, R. Tonini, M. Gherardi, V. Colombo The investigation of the efficiency of a handheld Plasma Gun (PG) in the decontamination of tooth root canals is here reported. The antibacterial efficacy of the PG was first assessed on Enterococcus faecalis contaminated agar plates to determine optimal operating conditions that were then quantitatively evaluated treating contaminated liquid suspensions. Moreover, two different procedures for th...
Source: Clinical Plasma Medicine - December 14, 2015 Category: Research Source Type: research
Call for trials – Strategic criteria of clinical studies using physical plasma in head and neck cancer
Publication date: Available online 23 November 2015 Source:Clinical Plasma Medicine Author(s): Christian Seebauer, Matthias Schuster, Rico Rutkowski, Maria Mksoud, David S. Nedrelow, Philine H. Metelmann (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - December 14, 2015 Category: Research Source Type: research
Focus issue: “Plasma–liquid interactions: Key role in plasma medical research and new fields of application”
Publication date: Available online 23 November 2015 Source:Clinical Plasma Medicine Author(s): Thomas von Woedtke, Hans-Robert Metelmann (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - December 14, 2015 Category: Research Source Type: research
Research on plasma medicine-relevant plasma–liquid interaction: What happened in the past five years?
Publication date: Available online 23 November 2015 Source:Clinical Plasma Medicine Author(s): Helena Jablonowski, Thomas von Woedtke During the last five years mechanisms of plasma-induced change of liquid chemistry have drawn huge attention in basic research in plasma medicine because liquid phase processes have been identified to be the main key to understand detailed mechanisms of atmospheric pressure plasma effects on living systems. Moreover, plasma-activated liquids are considered to be useful for several applications also in the medical field. This review gives a compilation of the work done in the past fiv...
Source: Clinical Plasma Medicine - December 14, 2015 Category: Research Source Type: research
Bactericidal efficacy of cold plasma in processed bone. A new approach for adjuvant therapy of medication-related osteonecrosis of the jaw?
Conclusion These results suggest that cold atmospheric pressure plasma has profound effectiveness on the bacterially contaminated bone in vitro. The use on cancellous bone is possibly a promising technique and could be a useful tool in the therapeutic range for the treatment of medication-related osteonecrosis of the jaw. (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - December 14, 2015 Category: Research Source Type: research
Investigation of air-DBD effects on biological liquids for in vitro studies on eukaryotic cells
Publication date: Available online 3 October 2015 Source:Clinical Plasma Medicine Author(s): Ilaria Trizio, Eloisa Sardella, Edda Francioso, Giorgio Dilecce, Vito Rizzi, Pinalysa Cosma, Michael Schmidt, Mareike Hänsch, Thomas von Woedtke, Pietro Favia, Roberto Gristina Atmospheric pressure (AP) Dielectric Barrier Discharges (DBD) generated in air were performed on water, Phosphate Buffer Saline (PBS) and Dulbecco's Modified Eagle's Medium (DMEM) in order to evaluate their potential to generate hydrogen peroxide (H2O2), nitrite (NO2 -) and nitrate (NO3 -) species. Differences in cell growth and mo...
Source: Clinical Plasma Medicine - October 4, 2015 Category: Research Source Type: research
Non-thermal microwave argon plasma affects interactions of listeria monocytogenes with mammalian cells but it does not kill the intracellular pathogen
Publication date: Available online 14 September 2015 Source:Clinical Plasma Medicine Author(s): Elena Sysolyatina, Konstantin Sobyanin, Mikhail Vasiliev, Oleg Petrov, Gregor Morfill, Vladimir Fortov, Alexander Gintsburg, Svetlana Emolaeva Effects of microwave argon non-thermal plasma (NTP) on the facultative intracellular pathogen Listeria monocytogenes were studied. NTP treatment for 2 minutes caused a 3log10 decrease of wild type strain EGDe extracellular bacteria. Similar treatment of infected HEK293 cells caused a 1.5-fold decrease of intracellular EGDe bacteria. The intraphagosomal EGDeΔhly lacked...
Source: Clinical Plasma Medicine - September 15, 2015 Category: Research Source Type: research
Plasma with High electron density and Plasma-Activated Medium for Cancer Treatment
Publication date: Available online 11 September 2015 Source:Clinical Plasma Medicine Author(s): Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Hiroki Kondo, Keigo Takeda, Hiroshi Hashizume, Kae Nakamura, Fumi Utsumi, Hiroaki Kajiyama, Hiroyuki Kano, Yasumasa Okazaki, Shinya Toyokuni, Shin’ichi Akiyama, Shoichi Maruyama, Suguru Yamada, Yasuhiro Kodera, Hiroki Kaneko, Hiroko Terasaki, Hirokazu Hara, Tetsuo Adachi, Machiko Iida, Ichiro Yajima, Masashi Kato, Fumitaka Kikkawa, Masaru Hori Cancer treatment using non-thermal atmospheric pressure plasma is a brand new and c...
Source: Clinical Plasma Medicine - September 12, 2015 Category: Research Source Type: research
Clinical plasma medicine—position and perspectives in 2012
Publication date: June 2013 Source:Clinical Plasma Medicine, Volume 1, Issue 1 Author(s): Steffen Emmert, Georg Isbary, Franziska Kluschke, Jürgen Lademann, Fred Podmelle, Hans-Robert Metelmann, Georg Daeschlein, Kai Masur, Thomas von Woedtke, Klaus-Dieter Weltmann (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - July 29, 2015 Category: Research Source Type: research
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Publication date: June 2015 Source:Clinical Plasma Medicine, Volume 3, Issue 1 (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - June 20, 2015 Category: Research Source Type: research
Cell migration and adhesion of a Human melanoma cell line Is decreased by cold plasma treatment
Publication date: Available online 27 May 2015 Source:Clinical Plasma Medicine Author(s): Anke Schmidt , Sander Bekeschus , Thomas von Woedtke , Sybille Hasse Treatment of tumor metastasis continues to be of major importance in the field of cancer medicine. The biological responses of the human melanoma cancer cell line SK-Mel-147 after exposure to cold plasma-treated medium were investigated. Plasma reduced tumor cell motility and colony formation while cell metabolism, apoptosis, and cell cycle progression were less affected. Plasma treatment was associated with an inhibition of migration and disorganization of t...
Source: Clinical Plasma Medicine - May 29, 2015 Category: Research Source Type: research
Plasma treatment of dentin surfaces for improving self-etching adhesive/dentin interface bonding
This study is to evaluate plasma treatment effects on dentin surfaces for improving self-etching adhesive and dentin interface bonding. Extracted unerupted human third molars were used after crown removal to expose dentin. One half of each dentin surface was treated with atmospheric non-thermal argon plasmas, while another half was untreated and used as the same tooth control. Self-etching adhesive and universal resin composite was applied to the dentin surfaces as directed. After restoration, the adhesive-dentin bonding strength was evaluated by micro-tensile bonding strength (μTBS) test. Bonding strength data was analyz...
Source: Clinical Plasma Medicine - May 23, 2015 Category: Research Source Type: research
Air pLASMA-GENERATED nITRIC OXIDE IN TREATMENT OF SKIN SCARS AND ARTICULAR MUSCULOSKELETAL DISORDERS: PRELIMINARY rEVIEW OF OBSERVATIONS
Publication date: Available online 14 May 2015 Source:Clinical Plasma Medicine Author(s): Victor N. Vasilets , Anatoly B. Shekhter , Anna E. Guller , Alexander V. Pekshev The generation of gaseous mixtures containing nitric oxide (gNO) from different plasma sources has been widely used for various clinical applications. Concentrations of biologically active species generated in those discharges in addition to gNO were calculated for different gas temperatures. Synergistic actions of gNO with other plasma species are discussed. New therapeutic effects of gNO-containing plasmas achieved for the treatment of skin scar...
Source: Clinical Plasma Medicine - May 14, 2015 Category: Research Source Type: research
