Perspectives of endoscopic plasma applications
Publication date: December 2013 Source:Clinical Plasma Medicine, Volume 1, Issue 2 Author(s): E. Robert , M. Vandamme , L. Brullé , S. Lerondel , A. Le Pape , V. Sarron , D. Riès , T. Darny , S. Dozias , G. Collet , C. Kieda , J.M. Pouvesle The development of the Plasma Gun, generating Pulsed Atmospheric-pressure Plasma Streams inside long and small diameter tubes flushed with low gas flow rates, is reported with a special emphasis on the first demonstration and perspectives for in vivo endoscopic applications. The safe delivery and antitumor action of plasma have been achieved for in vivo colorectal and ...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Plasma in cancer treatment
Publication date: December 2013 Source:Clinical Plasma Medicine, Volume 1, Issue 2 Author(s): Jürgen Schlegel , Julia Köritzer , Veronika Boxhammer "Plasma oncology", i.e., the use of cold atmospheric plasma (CAP) for the treatment of tumours is a new field in plasma medicine. The results of several studies that are summarized within this review show that CAP is effective against tumour cells both in vitro and in vivo. It has been shown, that CAP in low concentration is able to stop tumour cells growing, to induce cell death in higher concentrations and that this is more effective than standard therapies. Moreover...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

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Publication date: December 2013 Source:Clinical Plasma Medicine, Volume 1, Issue 2 Author(s): Thomas von Woedtke , Hans-Robert Metelmann (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Letter to the editors
Publication date: July 2014 Source:Clinical Plasma Medicine, Volume 2, Issue 1 (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Cold plasma on full-thickness cutaneous wound accelerates healing through promoting inflammation, re-epithelialization and wound contraction
Publication date: July 2014 Source:Clinical Plasma Medicine, Volume 2, Issue 1 Author(s): Nasruddin , Yukari Nakajima , Kanae Mukai , Heni Setyowati Esti Rahayu , Muhammad Nur , Tatsuo Ishijima , Hiroshi Enomoto , Yoshihiko Uesugi , Junko Sugama , Toshio Nakatani We investigated cold plasma effects on acute wounds of mice. The mice were classified into experimental and control groups. In the former, wounds were treated using cold plasma once daily for 1min, and then covered with hydrocolloid dressing; wounds in the control were left to heal under hydrocolloid dressing. Daily evaluation was conducted for 15 day...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Effects of tissue-tolerable plasma on psoriasis vulgaris treatment compared to conventional local treatment: A pilot study
Publication date: July 2014 Source:Clinical Plasma Medicine, Volume 2, Issue 1 Author(s): M. Klebes , J. Lademann , S. Philipp , C. Ulrich , A. Patzelt , M. Ulmer , F. Kluschke , A. Kramer , K.D. Weltmann , W. Sterry , B. Lange-Asschenfeldt The effect of tissue-tolerable plasma (TTP) on inflammatory diseases such as psoriasis was investigated. Three plaques of six psoriatic patients were subjected to different treatments (A: TTP, brine baths (BB)+5% salicylic acid ointment (SAO); B: BB+SAO; C: BB, UV irradiation, SAO+dithranol). While redness and infiltration was reduced in groups A and C, scaling was reduce...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Antimicrobial effects of non-thermal atmospheric plasma as a novel root canal disinfectant
This study aimed to investigate effects of non-thermal atmospheric plasma on an Enterococcus faecalis biofilm within the canals of extracted human teeth. A significant decrease in the number of CFU׳s was observed after 2min cold plasma treatment with an average kill rate of 99.999%. MTT assay showed a significant reduction in the viability of bacteria with a reduction rate of 98.939%. XTT assay showed a reduction of bacterial metabolic activity by 99.7%. Both 2min cold plasma and 6% NaOCl greatly reduced the viability and metabolic activity of E. faecalis bacteria, but there is no significant difference between them. (Sou...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

A mechanistic study of plasma treatment effects on demineralized dentin surfaces for improved adhesive/dentin interface bonding
This study is to achieve mechanistic understanding of the plasma treatment effects on dentin surface through investigating the plasma treated dentin surfaces and their interaction with adhesive monomer, 2-hydroxyethyl methacrylate (HEMA). The plasma treated dentin surfaces from human third molars were evaluated by water contact angle measurements and scanning electron microscopy (SEM). It was found that plasma-treated dentin surface with subsequent HEMA immersion (Plasma/HEMA Treated) had much lower water contact angle compared with only plasma-treated (Plasma Treated) or only HEMA immersed (HEMA Treated) dentin surfaces. ...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Plasma in dentistry
Publication date: July 2014 Source:Clinical Plasma Medicine, Volume 2, Issue 1 Author(s): Seunghee Cha , Young-Seok Park This review describes the contemporary aspects of plasma application in dentistry. Previous studies on plasma applications were classified into two categories, surface treatment and direct applications, and were reviewed, respectively according to the approach. The current review discussed modification of dental implant surface, enhancing of adhesive qualities, enhancing of polymerization, surface coating and plasma cleaning under the topics of surface treatment. Microbicidal activities, decontamin...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Guest editorial
Publication date: July 2014 Source:Clinical Plasma Medicine, Volume 2, Issue 1 Author(s): Stefan Rupf (Source: Clinical Plasma Medicine)
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Randomized placebo-controlled clinical trial showed cold atmospheric argon plasma relieved acute pain and accelerated healing in herpes zoster
In this study, weekday 5min plasma treatments with the MicroPlaSter ß device was assessed for safety, pain reduction and healing rates of herpes zoster. 37 inpatients with herpes zoster were treated in a prospective randomized placebo-controlled phase II study with either weekday 5min of cold atmospheric argon plasma (19, active) or with 5min of argon gas (18, placebo), in addition to a standard treatment regime. Pain was assessed by visual analogue scale before and after active or placebo application. Digital images of lesions were evaluated independently by three blinded clinicians, with regard to vesicles, erythema and...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research

Decomposition of sugars under non-thermal dielectric barrier discharge plasma
Publication date: Available online 30 September 2014 Source:Clinical Plasma Medicine Author(s): Yingying Li , Gary Friedman , Alex Fridman , Hai-Feng Ji Solutions of ribose, glucose, and sucrose in water and phosphate buffer were treated with non-thermal plasma generated by using a dielectric barrier discharge (DBD) device and the oxidation products were characterized by 1H NMR and GC–MS. Our results demonstrate that these sugars are decomposed to formic acid, glycolic acid, glyceric acid, tartronic acid, tartaric acid, acetic acid, and oxalic acid after direct exposure to DBD plasma. The concentrations of these ...
Source: Clinical Plasma Medicine - November 1, 2014 Category: Research Source Type: research