Research on plasma medicine-relevant plasma –liquid interaction: What happened in the past five years?

Publication date: December 2015 Source:Clinical Plasma Medicine, Volume 3, Issue 2 Author(s): Helena Jablonowski, Thomas von Woedtke During the last five years mechanisms of plasma-induced change of liquid chemistry have drawn huge attention in basic research in plasma medicine because liquid phase processes have been identified to be the main key to understand detailed mechanisms of atmospheric pressure plasma effects on living systems. Moreover, plasma-activated liquids are considered to be useful for several applications also in the medical field. This review gives a compilation of the work done in the past five years mainly from an analytical point of view to reveal both the actual knowledge and the still missing parts for a more complete understanding of the plasma–liquid-tissue interaction. In general, independent both on the different atmospheric pressure plasma sources (dielectric barrier discharges, plasma jets; different working gases) and the different liquid systems (water, non-buffered and buffered saline solutions, cell culture media) investigated, hydrogen peroxide (H2O2) as well as nitrite (NO2 −) and nitrate (NO3 −) were detected as stable reactive oxygen and nitrogen species (ROS, RNS/RONS). In non-buffered systems, pH decrease was found. It is hypothesized that the basic pathways of generation of reactive species in liquids after treatment with atmospheric pressure plasmas can be generalized. These stable and easy to detect ROS and RNS/RONS ar...

Source: Clinical Plasma Medicine - July 20, 2016 Category: Research Source Type: research