Can Fundus Fluorescein Angiography be Performed for Diabetic Patients on Oral Metformin?
This article analyzed contrast-induced nephropathy(CIN) and the related contrast agent, as well as the adverse reactions of fluorescein angiography. It pointed out that the discrepancy may be caused by misunderstanding of contrast agents used in FFA. For angiography using iodine contrast agent, metformin must be stopped because of the increased possibility of CIN, while for FFA using fluorescein sodium, no CIN has been reported yet. Therefore, the authors believe FFA is safe for diabetic patients with oral metformin and it is unnecessary to stop metformin before the examination. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
The Characteristics of Blood Supply and Tissue Hypoxia in Pathological Scars
Publication date: June 2017 Source:Chinese Medical Sciences Journal, Volume 32, Issue 2 Author(s): Zifei Li, Qingliang Liu, Xiaojun Wang, Jie Luan Blood supply is believed to be an important aspect in the development of pathological scars. However, there are controversies about vascular distribution, vascular structure and blood flow in pathological scars. Additionally, hypoxic microenvironment plays an important role in the vascularization of pathological scar tissues, and hypoxic conditions can be reflected by metabolic indexes and some cytokines. Furthermore, the correlation between blood supply and tissue hypoxia...
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
Prevalence of Carbapenem-Resistant Klebsiella Pneumoniae (CRKP) and the Distribution of Class 1 Integron in Their Strains Isolated from a Hospital in Central China
Conclusions CRKP has an increasing trend in a clinical setting in China, and most of them were resistant to multiple antibiotics. Class 1 integron in CRKP has strong ability to capture the genes resistant to aminoglycosides antibiotics from environment, with the aadA2 gene as the most popular one. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
Clinical Evaluation of Color Doppler Ultrasound in Selecting the Optimal Treatment Modality for Infantile Hemangioma
Conclusion With the guidance of color Doppler ultrasound, the efficacy and safety of long pulse 1064 nmNd:YAG laser, intense pulsed light, and lauromacrogol injection in the treatment of infantile hemangioma have better outcomes compared to laser treatment alone without preoperative ultrasound examination. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
Neuroprotective Effects of Grape Seed Procyanidin Extract on Ischemia-Reperfusion Brain Injury
Conclusion GSPE administration protects mice from ischemia-reperfusion brain injury through attenuating oxidative stress and apoptosis, promoting angiogenesis, and activating antioxidant enzyme GSH-Px. GSPE may represent a new therapeutical direction for the treatment of ischemia-reperfusion brain injury. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
Effects of Aging on the Proliferation and Differentiation Capacity of Human Periodontal Ligament Stem Cells
Conclusion Human PDLSC could be successfully isolated from periodontal ligament tissues of different aged donors. However, the proliferation and osteogenic differentiation capacity of PDLSC decreased while donor aging. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
Abnormal Alterations of Cortical Thickness in 16 Patients with Type 2 Diabetes Mellitus: A Pilot MRI Study
Conclusion A widespread cortical thinning was revealed in patients with T2DM by the analysis of brain cortical thickness on MR. Our finding supports the idea that T2DM could lead to subtle diabetic brain structural changes. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
The Correlation of Indices in r-TEG with Intra-operative Blood Loss in Neurosurgical Patients
Conclusions Peri-operative change of α-angle, as an index of r-TEG, exhibited a significant negative correlation with intra-operative blood loss. The impact of hemorrhage on fibrinogen, instead of clotting factors, should be scrutinized. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 13, 2017 Category: General Medicine Source Type: research
IgG4-related Autoimmune Pancreatitis Mimicking Acute Pancreatitis: A Case Report
Publication date: March 2017 Source:Chinese Medical Sciences Journal, Volume 32, Issue 1 Author(s): Xing Chen, Lihua Wang, Lixian Zhang, Caihong Zhao (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
Anesthetic Management of Patients with Anti-N-methyl-D-aspartate Receptor Encephalitis: A Report of Two Cases
Publication date: March 2017 Source:Chinese Medical Sciences Journal, Volume 32, Issue 1 Author(s): Xiaoling Zhang, Jian Li, Dongxin Wang (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
Immunosuppressive Treatment of Non-infectious Uveitis: History and Current Choices
Publication date: March 2017 Source:Chinese Medical Sciences Journal, Volume 32, Issue 1 Author(s): Chan Zhao, Meifen Zhang Non-infectious uveitis is one of the leading causes of preventable blindness worldwide. Long-term immunosuppressive treatment is generally required to achieve durable control of inflammation in posterior and panuveitis. Although systemic corticosteroids have been the gold standard of immunosuppressive treatment for uveitis since first introduced in 1950s, its side effects of long-term use often warrant an adjuvant treatment to reduce the dosage/duration of corticosteroids needed to maintain diseas...
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
Up-regulation of Let-7a Expression Induces Gastric Carcinoma Cell Apoptosis In Vitro
Conclusion Up-regulating let-7a expression promoted apoptosis in SGC-7901 cells. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
microRNA-18a Promotes Cell Migration and Invasion Through Inhibiting Dicer l Expression in Hepatocellular Carcinoma In Vitro
Conclusion Our findings suggest that miR-18a promotes migration and invasion of HCC cells by inhibiting Dicer l expression. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
Value of Multi-detector CT in Detection of Isolated Spontaneous Superior Mesenteric Artery Dissection
Conclusion Multi-detector CT is a valuable method in diagnosis and classification of ISSMAD and monitoring the changes of dissection. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
Efficacy and Safety of SGLT2 Inhibitors in Patients with Type 1 Diabetes: A Meta-analysis of Randomized Controlled Trials
Conclusion SGLT2 inhibitors combined with insulin might be an efficient and safe treatment modality for T1DM patients. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2017 Category: General Medicine Source Type: research
