Trends and Prospects of Stem Cell Research in China
Publication date: June 2016 Source:Chinese Medical Sciences Journal, Volume 31, Issue 2 Author(s): Jing-wen Cao, Lu Zhang, Ye Li, Qing Yang, Wen-hua Fu, Xiao-chen Wang, Wen-long Huang Great progresses have been made in fundamental and clinical stem cell research in China in recent years. The official policy on stem cells, which was announced in 2015, seems as the spring of stem cell therapy in China. However, the regulation, governance, and management of clinical expectations are still challenging. This review summarized the current stem cell research and development in the field, as well as its rapidly e...
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Low-dose Simvastatin Increases Skeletal Muscle Sensitivity to Caffeine and Halothane
Conclusions The myotoxic side effect of simvastatin was found to change the sensitivity of myotubes in response to high-dose caffeine and halothane. When dose was low, sensitivity increased mainly because of increased Ca2+ content in the sarcoplasmic reticulum, which might explain why some individuals with statin-induced myotoxic symptoms may show positive caffeine-halothane contracture test results. However, when the dose was high and the damage to the myotubes was severer, sensitivity was lower. It is here supposed that the damage itself might put individuals with statin-induced myotoxic symptoms at greater risks of pres...
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Mechanical Strain Regulates Osteoblast Proliferation Through Ca2+-CaMK-CREB Signal Pathway
Conclusion The mechanical strain regulates osteoblasts proliferation through Ca2+-CaMK-CREB signal pathway via Ca2+ channel and PLC/IP3 transduction cascades. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Effect of 4-week Whole Body Vibration on Distal Radius Density
Conclusion A 4-week whole body vibration was feasible and contributed to increase of rBMD. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Impact of Intraoperative Blood Pressure Control and Temporary Parent Artery Blocking on Prognosis in Cerebral Aneurysms Surgery
Conclusions Timely controlled hypertension after aneurysm clipping and embolization can significantly shorten the stay time in ICU. The degree of controlled hypotension associates with postoperative mortality, the greater systolic blood pressure difference before and after antihypertensive treatment is, the higher the mortality will be. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Effect of Point-of-care Hemoglobin/Hematocrit Devices and Autologous Blood Salvage on Reduction of Perioperative Allogeneic Blood Transfusion
Conclusion Intraoperative usage of POC HGB/HCT devices and increasing autologous transfusion ratio could reduce perioperative allogeneic blood transfusion. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Determinants of Detection of Stones and Calcifications in the Hepatobiliary System on Virtual Nonenhanced Dual-energy CT
Conclusions Although the CT values and CNR of the lesions decreased in VNE images, the lesions of which attenuation greater than 229.21 HU and size larger than 0.15 cm2 could be detected with good reliability and obvious dose reduction. There was good consistency in the size of stones and calcifications in hepatobiliary system between VNE images and TNE images, which ensured the possibility of the clinical application of VNE images. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Clinical Characteristics of 261 Cases of Hospitalized Patients with Type 1 Diabetes Mellitus
Conclusions Compared with the non-adult onset T1DM patients, the islet function of adult onset patients was even worse. In the T1DM antibodies positive patients, the islet β cell function decreased more rapidly, so the antibodies could not only clarify the diagnosis of T1DM and also predict prognosis of the islet β cell function. In the management of T1DM patients, regular hospital revisits contributed to get better glycemic control and reduced the occurrence of diabetic complications. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 9, 2016 Category: Journals (General) Source Type: research
Effect of Autophagy Over Liver Diseases
This article states the effect of autophagy on liver diseases (hepatic fibrosis, fatty liver, viral hepatitis, and liver cancer), which aims to provide a new direction for the treatment of liver diseases. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
Roles of Long-chain Acyl Coenzyme A Synthetase in Absorption and Transport of Fatty Acid
Publication date: March 2016 Source:Chinese Medical Sciences Journal, Volume 31, Issue 1 Author(s): Fan Gao, Xue-feng Yang, Nian Fu, Yang Hu, Yan Ouyang, Kai Qing Abstract Long-chain acyl coenzyme A synthetase (ACSL) is a member of the synthetase family encoded by a multigene family; it plays an important role in the absorption and transport of fatty acid. Here we review the roles of ACSL in the regulating absorption and transport of fatty acid, as well as the connection between ACSL and some metabolic diseases. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
Treatment of Breast Cancer Accompanied by POEMS Syndrome: A Case Report
Publication date: March 2016 Source:Chinese Medical Sciences Journal, Volume 31, Issue 1 Author(s): Jian-yu Dong, Yan Yan, Min-feng Liu, Zhao-ze Guo, Jing-yun Guo, Chang-sheng Ye (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
Pathology Verified Concomitant Papillary Thyroid Carcinoma in the Sonographically Suspected Thyroid Lymphoma: A Case Report
Publication date: March 2016 Source:Chinese Medical Sciences Journal, Volume 31, Issue 1 Author(s): Qiong Wu, Yu-xin Jiang, Jun-chao Guo, Yu Xiao, Xiao Yang, Rui-na Zhao, Xing-jian Lai, Shen-ling Zhu, Xiao-yan Zhang, Bo Zhang (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
Therapy and Prevention of Postoperative Urosepsis of Ureter Endoscopic Lithotripsy for “Non-infection”
Conclusions Stone and operation themselves are potential factors to cause urosepsis after ureter endoscopic lithotripsy. Especially for patients who had not presented infection preoperatively, careful preparation preoperatively, corrective manipulation, low pressure irrigation, drainage and controlling time during operation, and early diagnosis, appropriate treatment postoperatively are the key to cure and prevent urosepsis. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
Life-threatening Spontaneous Retroperitoneal Haemorrhage: Role of Multidetector CT-angiography for the Emergency Management
Conclusion MDCTA was useful in the diagnosis of SRH and proved to be predictive for the outcome of conservative treatment and early intervention. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
Respiratory and Cardiac Characteristics of ICU Patients Aged 90 Years and Older: A Report of 12 Cases
Conclusions Elderly patients in shock tend to develop Takotsubo cardiomyopathy. Diastolic heart dysfunction might be a major contributor to difficult weaning from ventilator in elderly patients. Bedside lung ultrasonography and echocardiography could help decide the actual cause of respiratory failure and shock more accurately and effectively. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 5, 2016 Category: Journals (General) Source Type: research
