Extrarenal Wilms' Tumor of the Female Genital System: A Case Report and Literature Review
Publication date: December 2017Source: Chinese Medical Sciences Journal, Volume 32, Issue 4Author(s): Minmin Cao, Cuiping Huang, Yafen Wang, Demei MaAbstractExtrarenal Wilms' Tumors (ERWTs) are rare. There have been only 25 cases of ERWT arising from the female genital system reported in the literature. In this paper, we report a 60-year-old woman with a complaint of vaginal bleeding and a polypoid mass in the uterine cavity by sonography that was demonstrated as ERWT by pathology after resection. The pathological characteristics, histological origination, diagnosis, therapy and prognosis of ERWT in female reproductive sys...
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Recombinant Expression and Purification of Mouse Nectin-like 4 Glycoprotein in 293ET Cell Line
ConclusionsBy using modified AP mammalian protein expression system, we can easily screen the high productive stable cell lines by using AP activity assay. By adding mannosidase inhibitor kifunensine into the medium and cutting purified protein by using endoglycosidase H, we can obtain deglycosylated Necl-4 protein in milligram quantities. Our method might throw a light on the expression and purification of glycoprotein for structural and functional studies. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Therapy of Rituximab in Idiopathic Membranous Nephropathy with Nephrotic Syndrome: A Systematic Review and Meta-analysis
ConclusionsRTX treatment in IMN was efficient, well tolerated and safe. More than 60% patients can reach partial remission or CR in 24 months, and relapse is rare. Adverse events of RTX are mostly infusion-related reactions and generally mild. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Gray Matter Volume Changes over the Whole Brain in the Bulbar- and Spinal-onset Amyotrophic Lateral Sclerosis: a Voxel-based Morphometry Study
ConclusionsThe asymmetric GM atrophy of the motor cortex and extra-motor cortex represents the common MRI structural signatures of spinal-onset ALS, and sole extra-motor cortex atrophy represents the structural signatures of bulbar-onset ALS. The present study also demonstrated that the pattern of GM damage is likely to distribute wider in spinal-onset ALS than in bulbar-onset ALS. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Astragaloside IV Protects Against Aβ1-42-induced Oxidative Stress, Neuroinflammation and Cognitive Impairment in Rats
ConclusionOur findings suggest that AS-IV might be a useful chemical in improving the spatial memory and relieving the oxidative stress and neuroinflammation in Alzheimer patients. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Reliability of Three Dimentional Pseudo-continuous Arterial Spin Labeling: A Volumetric Cerebral Perfusion Imaging with Different Post-labeling Time and Functional State in Health Adults
ConclusionThis work demonstrated that 3D pc-ASL might be a reliable imaging technique to measure CBF over the whole brain at different PLD in the resting state or controlled state. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Gene Expression Profile of Hypertrophic Chondrocytes Treated with H2O2: A Preliminary Investigation
ConclusionsH2O2 significantly changed the expression of several genes involved in a variety of biological functions. Because of the link between oxidative damage and Kashin-Beck disease, these genes may also be involved in the deep-zone necrosis of the cartilage observed in Kashin-Beck disease. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Progress in the Diagnosis and Management of Chorea-acanthocytosis
Publication date: March 2018Source: Chinese Medical Sciences Journal, Volume 33, Issue 1Author(s): Yang Liu, Ziyuan Liu, Xinhua Wan, Yi GuoAbstractChorea-acanthocytosis (ChAc) is the most common subtype of neuroacanthocytosis syndrome, characterized by the presence of acanthocytes and neurological disorders. It is thought to be caused by VPS13A mutations. Characteristic movement disorders in ChAc is choreiform movements affecting both trunk and extremities and prominent orolingual dyskinesia is pathognomonic. Acanthocytosis in peripheral blood smear, elevated serum creatine kinase and atrophy of heads of caudate nuclei and...
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Fibronectin Glomerulopathy Caused by the Y973C Mutation in Fibronectin: A Case Report and Literature Review
Publication date: March 2018Source: Chinese Medical Sciences Journal, Volume 33, Issue 1Author(s): Chao Li, Yubing Wen, Hang Li, Mingxi Li, Xuewang Li, Xuemei LiAbstractFibronectin glomerulopathy is a rare autosomal dominant inherited glomerular disease associated with massive deposition of fibronectin. We recently diagnosed fibronectin glomerulopathy in a 29-year-old woman presenting nephrotic syndrome. Genetic analysis of fibronectin 1 gene showed heterozygosity for the Y973C mutation. However, this mutation was not found in her parents. She had stable renal function but persistent nephrotic proteinuria after one-year fo...
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Solitary Fibrous Tumor of the Kidney Treated with Laparoscopic Partial Nephrectomy: A Case Report
Publication date: March 2018Source: Chinese Medical Sciences Journal, Volume 33, Issue 1Author(s): Xing Chen, Jianfeng Wang, Zhenshan Ding, Xiaofeng ZhouAbstractWe herein reported a 27-year-old woman with a right renal mass for two years. She underwent laparoscopic partial nephrectomy. Immunohistochemical examination of the specimen confirmed the diagnosis of solitary fibrous tumor by revealing its positive staining for cluster of differentiation (CD)34, epithelial membrane antigen (EMA), B-cell lymphoma-2 (Bcl-2) and CD99 in the tumor cells. No adjuvant treatment was carried out. The patient was in good health without loc...
Source: Chinese Medical Sciences Journal - July 5, 2018 Category: General Medicine Source Type: research
Solitary Fibrous Tumor of the Kidney Treated with Laparoscopic Partial Nephrectomy: A Case Report
Publication date: March 2018 Source:Chinese Medical Sciences Journal, Volume 33, Issue 1 Author(s): Xing Chen, Jianfeng Wang, Zhenshan Ding, Xiaofeng Zhou We herein reported a 27-year-old woman with a right renal mass for two years. She underwent laparoscopic partial nephrectomy. Immunohistochemical examination of the specimen confirmed the diagnosis of solitary fibrous tumor by revealing its positive staining for cluster of differentiation (CD)34, epithelial membrane antigen (EMA), B-cell lymphoma-2 (Bcl-2) and CD99 in the tumor cells. No adjuvant treatment was carried out. The patient was in good health without loc...
Source: Chinese Medical Sciences Journal - April 6, 2018 Category: General Medicine Source Type: research
Fibronectin Glomerulopathy Caused by the Y973C Mutation in Fibronectin: A Case Report and Literature Review
Publication date: March 2018 Source:Chinese Medical Sciences Journal, Volume 33, Issue 1 Author(s): Chao Li, Yubing Wen, Hang Li, Mingxi Li, Xuewang Li, Xuemei Li Fibronectin glomerulopathy is a rare autosomal dominant inherited glomerular disease associated with massive deposition of fibronectin. We recently diagnosed fibronectin glomerulopathy in a 29-year-old woman presenting nephrotic syndrome. Genetic analysis of fibronectin 1 gene showed heterozygosity for the Y973C mutation. However, this mutation was not found in her parents. She had stable renal function but persistent nephrotic proteinuria after one-year ...
Source: Chinese Medical Sciences Journal - April 6, 2018 Category: General Medicine Source Type: research
Progress in the Diagnosis and Management of Chorea-acanthocytosis
Publication date: March 2018 Source:Chinese Medical Sciences Journal, Volume 33, Issue 1 Author(s): Yang Liu, Ziyuan Liu, Xinhua Wan, Yi Guo Chorea-acanthocytosis (ChAc) is the most common subtype of neuroacanthocytosis syndrome, characterized by the presence of acanthocytes and neurological disorders. It is thought to be caused by VPS13A mutations. Characteristic movement disorders in ChAc is choreiform movements affecting both trunk and extremities and prominent orolingual dyskinesia is pathognomonic. Acanthocytosis in peripheral blood smear, elevated serum creatine kinase and atrophy of heads of caudate nuclei and...
Source: Chinese Medical Sciences Journal - April 6, 2018 Category: General Medicine Source Type: research
Gene Expression Profile of Hypertrophic Chondrocytes Treated with H2O2: A Preliminary Investigation
Conclusions H2O2 significantly changed the expression of several genes involved in a variety of biological functions. Because of the link between oxidative damage and Kashin-Beck disease, these genes may also be involved in the deep-zone necrosis of the cartilage observed in Kashin-Beck disease. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 6, 2018 Category: General Medicine Source Type: research
Reliability of Three Dimentional Pseudo-continuous Arterial Spin Labeling: A Volumetric Cerebral Perfusion Imaging with Different Post-labeling Time and Functional State in Health Adults
Conclusion This work demonstrated that 3D pc-ASL might be a reliable imaging technique to measure CBF over the whole brain at different PLD in the resting state or controlled state. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - April 6, 2018 Category: General Medicine Source Type: research
