Development of new 3D human ex vivo models to study sebaceous gland lipid metabolism and modulations
ConclusionFunctional sebocyte maturation and physiological maintenance were preserved up to 6 weeks in our models. Associated with functional assays, they provide a powerful platform to mimic physiological skin lipid metabolism and to screen for active ingredients modulating sebum production. (Source: Cell Proliferation)
Source: Cell Proliferation - November 6, 2018 Category: Cytology Authors: Anne ‐France Bengy,
Nico Forraz,
Louis Danoux,
Nicolas Berthelemy,
Sébastien Cadau,
Olivier Degoul,
Valérie Andre,
Sabine Pain,
Colin McGuckin Tags: ORIGINAL ARTICLE Source Type: research
Bidirectional regulation of osteogenic differentiation by the FOXO subfamily of Forkhead transcription factors in mammalian MSCs
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - November 6, 2018 Category: Cytology Authors: Duanjing Chen,
Yuanyuan Gong,
Ling Xu,
Mengjiao Zhou,
Jie Li,
Jinlin Song Source Type: research
Recent progress in the emerging role of exosome in hepatocellular carcinoma
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - November 6, 2018 Category: Cytology Authors: Mubalake Abudoureyimu,
Hao Zhou,
Yingru Zhi,
Ting Wang,
Bing Feng,
Rui Wang,
Xiaoyuan Chu Source Type: research
Effects of simulated microgravity on the expression profiles of RNA during osteogenic differentiation of human bone marrow mesenchymal stem cells
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - November 6, 2018 Category: Cytology Authors: Liang Li,
Cui Zhang,
Jian ‐ling Chen,
Fan‐fan Hong,
Ping Chen,
Jin‐fu Wang Source Type: research
Recent progress in the emerging role of exosome in hepatocellular carcinoma
AbstractExosomes are small membrane vesicles 50 ‐150 nm in diameter released by a variety of cells, which contain miRNAs, mRNAs and proteins with the potential to regulate signalling pathways in recipient cells. Exosomes deliver nucleic acids and proteins to participate in orchestrating cell‐cell communication and microenvironment modulation . In this review, we summarize recent progress in our understanding of the role of exosomes in hepatocellular carcinoma (HCC). This review focuses on recent studies on HCC exosomes, considering biogenesis, cargo and their effects on the development and progression of HCC, includin...
Source: Cell Proliferation - November 5, 2018 Category: Cytology Authors: Mubalake Abudoureyimu,
Hao Zhou,
Yingru Zhi,
Ting Wang,
Bing Feng,
Rui Wang,
Xiaoyuan Chu Tags: REVIEW ARTICLE Source Type: research
Effects of simulated microgravity on the expression profiles of RNA during osteogenic differentiation of human bone marrow mesenchymal stem cells
ConclusionOur data revealed that SMG inhibits the proliferation and inhibits the differentiation towards osteoblasts but promotes adipogenesis. SMG also selects highly tumorigenic cells for survival under prolonged SMG. (Source: Cell Proliferation)
Source: Cell Proliferation - November 5, 2018 Category: Cytology Authors: Liang Li,
Cui Zhang,
Jian ‐ling Chen,
Fan‐fan Hong,
Ping Chen,
Jin‐fu Wang Tags: ORIGINAL ARTICLE Source Type: research
Bidirectional regulation of osteogenic differentiation by the FOXO subfamily of Forkhead transcription factors in mammalian MSCs
AbstractThrough loss ‐ and gain‐of‐function experiments in knockout and transgenic mice, Forkhead box O (FOXO) family transcription factors have been demonstrated to play essential roles in many biological processes, including cellular proliferation, apoptosis and differentiation. Osteogenic differentiation from m esenchymal stem cells (MSCs) into osteoblasts is a well‐organized process that is carefully guided and characterized by various factors, such as runt‐related transcription factor 2 (Runx2), β‐catenin, osteocalcin (OCN), alkaline phosphatase (ALP) and activating transcription factor 4 (ATF4). Accumula...
Source: Cell Proliferation - November 5, 2018 Category: Cytology Authors: Duanjing Chen,
Yuanyuan Gong,
Ling Xu,
Mengjiao Zhou,
Jie Li,
Jinlin Song Tags: REVIEW ARTICLE Source Type: research
Emerging roles of long non ‐coding RNAs in neuropathic pain
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - October 26, 2018 Category: Cytology Authors: Zheng Li,
Xingye Li,
Xin Chen,
Shugang Li,
Idy H. T. Ho,
Xiaodong Liu,
Matthew T. V. Chan,
William K. K. Wu Source Type: research
LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF ‐κB/NLRP3 inflammasome pathway
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - October 26, 2018 Category: Cytology Authors: Mengru Ma,
Yifei Pei,
Xixi Wang,
Jiaxin Feng,
Yong Zhang,
Ming ‐Qing Gao Source Type: research
The spatiotemporal expression and mineralization regulation of p75 neurotrophin receptor in the early tooth development
Conclusionp75NTR might play an important role in the regulation of tooth morphogenesis, especially dental hard tissue formation. (Source: Cell Proliferation)
Source: Cell Proliferation - October 25, 2018 Category: Cytology Authors: Manzhu Zhao,
Xiujie Wen,
Gang Li,
Yingxin Ju,
Yingying Wang,
Zhi Zhou,
Jinlin Song Tags: ORIGINAL ARTICLE Source Type: research
Emerging roles of long non ‐coding RNAs in neuropathic pain
AbstractNeuropathic pain, a type of chronic and potentially disabling pain resulting from primary injury/dysfunction of the somatosensory nervous system and spinal cord injury, is one of the most intense types of chronic pain, which incurs a significant economic and public health burden. However, our understanding of its cellular and molecular pathogenesis is still far from complete. Long non ‐coding RNAs (lncRNAs) are important regulators of gene expression and have recently been characterized as key modulators of neuronal functions. Emerging evidence suggested that lncRNAs are deregulated and play pivotal roles in the ...
Source: Cell Proliferation - October 25, 2018 Category: Cytology Authors: Zheng Li,
Xingye Li,
Xin Chen,
Shugang Li,
Idy H. T. Ho,
Xiaodong Liu,
Matthew T. V. Chan,
William K. K. Wu Tags: REVIEW Source Type: research
LncRNA XIST mediates bovine mammary epithelial cell inflammatory response via NF ‐κB/NLRP3 inflammasome pathway
ConclusionsThe expression of XIST was promoted by activated NF ‐κB pathway and, in turn, XIST generated a negative feedback loop to regulate NF‐κB/NLRP3 inflammasome pathway for mediating the process of inflammation. (Source: Cell Proliferation)
Source: Cell Proliferation - October 25, 2018 Category: Cytology Authors: Mengru Ma,
Yifei Pei,
Xixi Wang,
Jiaxin Feng,
Yong Zhang,
Ming ‐Qing Gao Tags: ORIGINAL ARTICLE Source Type: research
The spatiotemporal expression and mineralization regulation of p75 neurotrophin receptor in the early tooth development
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - October 25, 2018 Category: Cytology Authors: Manzhu Zhao,
Xiujie Wen,
Gang Li,
Yingxin Ju,
Yingying Wang,
Zhi Zhou,
Jinlin Song Source Type: research
Golgi protein 73 and its diagnostic value in liver diseases
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - October 20, 2018 Category: Cytology Authors: Yanyan Xia,
Yuanying Zhang,
Mengjiao Shen,
Hongpan Xu,
Zhiyang Li,
Nongyue He Source Type: research
