Fak ‐Mapk, Hippo and Wnt signalling pathway expression and regulation in distraction osteogenesis
ConclusionIt was inferred that the mechanical stimulus induces increased expression of Fak and activates Fak‐Mapk pathway, by activation of Erk, Jnk and p38‐Mapk pathway, and that Fak at least, in part, plays an important role in maintaining osteogenic effect by activating Fak‐Mapk pathway during distraction osteogenesis. (Source: Cell Proliferation)
Source: Cell Proliferation - March 5, 2018 Category: Cytology Authors: Jian Song, Bin Ye, Hanghang Liu, Ruiye Bi, Nian Zhang, Jing Hu, En Luo Tags: ORIGINAL ARTICLE Source Type: research
Overcoming resistance to mitochondrial apoptosis by BZML ‐induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - March 1, 2018 Category: Cytology Source Type: research
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Cell Proliferation, Ahead of Print. (Source: Cell Proliferation)
Source: Cell Proliferation - March 1, 2018 Category: Cytology Source Type: research
Pharmacological or transcriptional inhibition of both HDAC1 and 2 leads to cell cycle blockage and apoptosis via p21Waf1/Cip1 and p19INK4d upregulation in hepatocellular carcinoma
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - February 27, 2018 Category: Cytology Source Type: research
The BRAF activated non ‐coding RNA: A pivotal long non‐coding RNA in human malignancies
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - February 27, 2018 Category: Cytology Source Type: research
Coroglaucigenin induces senescence and autophagy in colorectal cancer cells
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - February 27, 2018 Category: Cytology Source Type: research
The long non ‐coding RNA SPRY4‐IT1: An emerging player in tumorigenesis and osteosarcoma
Cell Proliferation, EarlyView. (Source: Cell Proliferation)
Source: Cell Proliferation - February 27, 2018 Category: Cytology Source Type: research
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Cell Proliferation, Ahead of Print. (Source: Cell Proliferation)
Source: Cell Proliferation - February 27, 2018 Category: Cytology Source Type: research
The long non ‐coding RNA SPRY4‐IT1: An emerging player in tumorigenesis and osteosarcoma
Abstract
Accumulating evidence from genome‐wide analysis and functional studies has begun to unveil the important role of long non‐coding RNAs (lncRNAs) in cancer development. The lncRNA SPRY4‐IT1 is derived from an intron of SPRY4 gene and was originally reported to be upregulated in melanoma in which it functioned as an oncogene. Since this discovery, an increasing number of studies have investigated the expression and function of SPRY4‐IT1 in human cancers. Aberrant expression of SPRY4‐IT1 has now been documented in different cancer types, including osteosarcoma, breast, renal, oesophageal and prostate cancers...
Source: Cell Proliferation - February 27, 2018 Category: Cytology Authors: Zheng Li, Jianxiong Shen, Matthew T. V. Chan, William Ka Kei Wu Tags: REVIEW ARTICLE Source Type: research
Coroglaucigenin induces senescence and autophagy in colorectal cancer cells
ConclusionsOur results demonstrate that CGN induces senescence and autophagy in colorectal cancer cells and indicate that combining it with an autophagy inhibitor may be a novel strategy suitable for CGN‐mediated anti‐cancer therapy. (Source: Cell Proliferation)
Source: Cell Proliferation - February 27, 2018 Category: Cytology Authors: Yong ‐Hao Huang, Jing Lei, Guo‐Hui Yi, Feng‐Ying Huang, Yue‐Nan Li, Cai‐Chun Wang, Yan Sun, Hao‐Fu Dai, Guang‐Hong Tan Tags: ORIGINAL ARTICLE Source Type: research
The BRAF activated non ‐coding RNA: A pivotal long non‐coding RNA in human malignancies
Abstract
Long non‐coding RNAs (lncRNAs) participate in the complex network of cancer and play an important role in tumourigenesis and progression. BRAF activated non‐coding RNA (BANCR), a 4‐exon transcript of 693‐bp, was first discovered as an oncogenic long non‐coding RNA in BRAFV600E melanomas cells in 2012 and was related to melanoma cell migration. Besides melanoma, increasing evidence has explored the potential role of BANCR in the development and progression of multiple other human malignancies, such as retinoblastoma, lung cancer, gastric cancer etc. since its discovery. The expression pattern of BANCR va...
Source: Cell Proliferation - February 27, 2018 Category: Cytology Authors: Xiu ‐Fen Liu, Ji‐Long Hao, Tian Xie, Om Prakash Pant, Cheng‐Bo Lu, Cheng‐Wei Lu, Dan‐Dan Zhou Tags: REVIEW ARTICLE Source Type: research
