Fak ‐Mapk, Hippo and Wnt signalling pathway expression and regulation in distraction osteogenesis

ConclusionIt was inferred that the mechanical stimulus induces increased expression of Fak and activates Fak‐Mapk pathway, by activation of Erk, Jnk and p38‐Mapk pathway, and that Fak at least, in part, plays an important role in maintaining osteogenic effect by activating Fak‐Mapk pathway during distraction osteogenesis.

Source: Cell Proliferation - March 5, 2018 Category: Cytology Authors: Jian Song, Bin Ye, Hanghang Liu, Ruiye Bi, Nian Zhang, Jing Hu, En Luo Tags: ORIGINAL ARTICLE Source Type: research