CDR1as is overexpressed in laryngeal squamous cell carcinoma to promote the tumour ’s progression via miR‐7 signals
ConclusionCDR1as is an oncogene that promotes LSCC progression by regulating miR ‐7 signals. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Jianzhong Zhang,
Huayong Hu,
Yaoxin Zhao,
Yulin Zhao Tags: ORIGINAL ARTICLE Source Type: research
Upregulated miR ‐1258 regulates cell cycle and inhibits cell proliferation by directly targeting E2F8 in CRC
ConclusionMiR ‐1258 may function as a suppressive factor by negatively controlling E2F8, thus, highlighting the potential role of miR‐1258 as a therapeutic target for human CRC. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Zhiyuan Zhang,
Jie Li,
Yuanjian Huang,
Wen Peng,
Wenwei Qian,
Jiou Gu,
Qingyuan Wang,
Tao Hu,
Dongjian Ji,
Bing Ji,
Yue Zhang,
Shijia Wang,
Yueming Sun Tags: ORIGINAL ARTICLE Source Type: research
LncRNA B4GALT1 ‐AS1 recruits HuR to promote osteosarcoma cells stemness and migration via enhancing YAP transcriptional activity
ConclusionsWe indicate that lncRNA B4GALT1 ‐AS1 promotes OS cells stemness and migrationvia recruiting HuR to enhance YAP activity. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Zhikun Li,
Yi Wang,
Ruixi Hu,
Ruijun Xu,
Wei Xu Tags: ORIGINAL ARTICLE Source Type: research
Tetrahedral DNA nanostructures facilitate neural stem cell migration via activating RHOA/ROCK2 signalling pathway
ConclusionsIn conclusion, TDNs could enter NSCs without the aid of other transfection reagents in large amounts, whereas only small amounts of ssDNA could enter the cells. TDNs taken up by NSCs activated the RHOA/ROCK2 signalling pathway, which had effects on the relevant genes and proteins expression, eventually promoting the migration of NE ‐4C stem cells. These findings suggested that TDNs have great potential in application for the repair and regeneration of neural tissue. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Wenjuan Ma,
Xueping Xie,
Xiaoru Shao,
Yuxin Zhang,
Chenchen Mao,
Yuxi Zhan,
Dan Zhao,
Mengting Liu,
Qianshun Li,
Yunfeng Lin Tags: ORIGINAL ARTICLE Source Type: research
Cathepsin B regulates non ‐canonical NLRP3 inflammasome pathway by modulating activation of caspase‐11 in Kupffer cells
ConclusionOur results suggest a critical role for cathepsin B as activators of proinflammatory caspases ‐11 and the regulatory effect in LPS‐induced caspases‐11‐dependent necrosis. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Nan Chen,
Zhibing Ou,
Wenfeng Zhang,
Xiwen Zhu,
Peizhi Li,
Jianping Gong Tags: ORIGINAL ARTICLE Source Type: research
Oestrogen receptor α regulates the odonto/osteogenic differentiation of stem cells from apical papilla via ERK and JNK MAPK pathways
ConclusionsTogether, the data accumulated here indicated that ER α can enhance the odonto/osteogenic differentiation of SCAPs via ERK and JNK MAPK pathways. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Yanqiu Wang,
Yadie Lu,
Zehan Li,
Yixiang Zhou,
Yongchun Gu,
Xiyao Pang,
Jintao Wu,
Romila Gobin,
Jinhua Yu Tags: ORIGINAL ARTICLE Source Type: research
Prolyl hydroxylases positively regulated LPS ‐induced inflammation in human gingival fibroblasts via TLR4/MyD88‐mediated AKT/NF‐κB and MAPK pathways
ConclusionsProlyl hydroxylases acted as a positive regulator in LPS ‐induced inflammation of HGFs via TLR4/MyD88‐mediated NF‐κB, MAPK and AKT signalling pathways and PHD2 among three isoforms was principally responsible for the effects. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Lingling Shang,
Ting Wang,
Dongdong Tong,
Wenyan Kang,
Qianyu Liang,
Shaohua Ge Tags: ORIGINAL ARTICLE Source Type: research
AMOT130 linking F ‐actin to YAP is involved in intervertebral disc degeneration
ConclusionsThis study showed that a mechanism by which Hippo pathway and F ‐actin synergize to modulate YAP activation and localization in the context of IDD and help to control NPCs proliferation. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Cong Zhang,
Feng Wang,
Zhiyang Xie,
Lu Chen,
Arjun Sinkemani,
Haomin Yu,
Xiaotao Wu Tags: ORIGINAL ARTICLE Source Type: research
Cover Image, Volume 51, Issue 6
The cover image is based on the Original ArticleTetrahedral DNA nanostructures facilitate neural stem cell migration via activating RHOA/ROCK2 signalling pathway by Wenjuan Ma et al.,https://doi.org/10.1111/cpr.12503. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Wenjuan Ma,
Xueping Xie,
Xiaoru Shao,
Yuxin Zhang,
Chenchen Mao,
Yuxi Zhan,
Dan Zhao,
Mengting Liu,
Qianshun Li,
Yunfeng Lin Tags: COVER IMAGE Source Type: research
Issue Information
Cell Proliferation, Volume 51, Issue 6, December 2018. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Tags: ISSUE INFORMATION Source Type: research
Melatonin protects mesenchymal stem cells from autophagy ‐mediated death under ischaemic ER‐stress conditions by increasing prion protein expression
ConclusionMelatonin protects against ER stress/autophagy ‐induced apoptotic cell death by augmenting PrPC expression. Thus, melatonin ‐treated MSCs could be a potential cell‐based therapeutic agent for ER stress–induced ischaemic diseases, and melatonin‐induced PrPC might be a key molecule in ameliorating ER stress and autophagy. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Jun Hee Lee,
Yeo Min Yoon,
Yong ‐Seok Han,
Seo Kyung Jung,
Sang Hun Lee Tags: ORIGINAL ARTICLE Source Type: research
Nuclear factor ‐kappa B‐dependent X‐box binding protein 1 signalling promotes the proliferation of nucleus pulposus cells under tumour necrosis factor alpha stimulation
ConclusionsUnfolded protein response reinforces the survival and proliferation of NPCs under TNF ‐α stimulation by activating the XBP1 pathway, and NF‐κB serves as a vital mediator in these events. The XBP1 signalling of UPR can be a novel therapeutic target in IDD. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Lu Chen,
Zhi ‐Yang Xie,
Lei Liu,
Lei Zhu,
Feng Wang,
Pan Fan,
Arjun Sinkemani,
Cong Zhang,
Xin Hong,
Xiao‐Tao Wu Tags: ORIGINAL ARTICLE Source Type: research
IL ‐33 guides osteogenesis and increases proliferation and pluripotency marker expression in dental stem cells
ConclusionsIL ‐33 treatment impairs osteogenesis of PDLSCs and DPSCs, while increases their clonogenicity, proliferation and pluripotency marker expression. After exposure to IL‐33, osteogenic capacity of cells stayed intact. NF‐κB and β‐catenin are implicated in the effects achieved by IL‐33 in PDLSC s and DPSCs. (Source: Cell Proliferation)
Source: Cell Proliferation - November 14, 2018 Category: Cytology Authors: Tamara Kukolj,
Drenka Trivanovi ć,
Slavko Mojsilović,
Ivana Okić Djordjević,
Hristina Obradović,
Jelena Krstić,
Aleksandra Jauković,
Diana Bugarski Tags: ORIGINAL ARTICLE Source Type: research
LncRNA NEAT1 promotes the tumorigenesis of colorectal cancer by sponging miR ‐193a‐3p
ConclusionOur findings demonstrate that lncRNA NEAT1 acts as an oncogenic role in CRC cells by sponging miR ‐193a and may represent a potential marker for CRC patients. (Source: Cell Proliferation)
Source: Cell Proliferation - November 8, 2018 Category: Cytology Authors: Hong ‐Mei Yu,
Chen Wang,
Zhen Yuan,
Guang‐Liang Chen,
Tao Ye,
Bi‐Wei Yang Tags: ORIGINAL ARTICLE Source Type: research
