Best Practice and Research. Clinical Rheumatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Assessment of structural damage progression in established rheumatoid arthritis by conventional radiography, computed tomography, and magnetic resonance imaging
Publication date: Available online 27 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Lykke Midtbøll Ørnbjerg, Mikkel ØstergaardAbstractStructural damage progression in patients with established rheumatoid arthritis (RA) has traditionally been assessed by conventional radiography (CR), which has proven its value in clinical practice and clinical trials over the past decades. The most prominent abnormalities visualized by CR in RA patients are erosions as a consequence of bone destruction and joint space narrowing (JSN) as a consequence of cartilage damage. Several validated scoring systems t...
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

When the first visit to the rheumatologist is established rheumatoid arthritis
Publication date: Available online 27 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Peter C. Taylor, Shing T. LawAbstractThe outlook for people living with rheumatoid arthritis (RA) has improved tremendously in a generation. Major contributions to this include recognition of the importance of early treatment initiation, improved understanding of the pathobiology, the identification of therapeutic targets and their subsequent validation in clinic trials and the realisation of the importance of ‘tight control’ of inflammatory responses. Despite these advances, many patients meeting classifi...
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

Established Rheumatoid Arthritis
Publication date: Available online 28 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ana M. Ortiz, Sebnem Ataman (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - January 28, 2020 Category: Rheumatology Source Type: research

Nonpharmacological treatment in established rheumatoid arthritis
Publication date: Available online 25 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ayşe A. KüçükdeveciAbstractThe goals in the management of established rheumatoid arthritis (RA) are to control pain and disease activity, prevent further joint damage, and enhance functioning and quality of life. Despite the fact that aggressive and the early use of biological and nonbiological disease-modifying antirheumatic drugs have been associated with substantial gains in clinical, radiological, and disability outcomes, a considerable proportion of patients still report significant problems of physic...
Source: Best Practice and Research Clinical Rheumatology - January 25, 2020 Category: Rheumatology Source Type: research

The epidemiology of established rheumatoid arthritis
Publication date: Available online 25 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): Teresa Otón, Loreto CarmonaAbstractNo published epidemiological study has specifically focused on the prevalence of established rheumatoid arthritis (RA), as epidemiologists do not study established RA separated from RA as a whole; especially no incidence studies can be found, as incidence refers to new cases (early RA). Such a study, if it existed, would find a prevalence much larger than that of recent-onset RA, and should be planned based on clear definitions that currently do not exist in epidemiology. As...
Source: Best Practice and Research Clinical Rheumatology - January 25, 2020 Category: Rheumatology Source Type: research

Autoantibodies in connective tissue disease
Publication date: Available online 14 December 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ben Mulhearn, Sarah L. Tansley, Neil J. McHughAbstractAutoimmune connective tissue diseases are heterogeneous rheumatic diseases with the potential to affect multiple body systems. Autoantibodies are a characteristic feature of these diseases and are typically highly disease specific. In addition to aiding diagnosis, many autoantibodies have established associations with clinically important disease complications including internal organ involvement. In this chapter, we review the autoantibodies relevant to a...
Source: Best Practice and Research Clinical Rheumatology - January 21, 2020 Category: Rheumatology Source Type: research

Systemic sclerosis: Advances towards stratified medicine
Publication date: Available online 21 January 2020Source: Best Practice & Research Clinical RheumatologyAuthor(s): A. Quinlivan, L. Ross, S. ProudmanAbstractEpidemiological studies reporting demographic, clinical and serological factors predictive of various outcomes in systemic sclerosis (SSc) range from the prediction of mortality to the development and progression of disease manifestations. However, predicting the disease trajectory in the individual patient is a challenging but important step towards a stratified approach to disease management. Recent technological advances provide the opportunity for new subgroupings ...
Source: Best Practice and Research Clinical Rheumatology - January 21, 2020 Category: Rheumatology Source Type: research

Antiphospholipid syndrome
Publication date: Available online 19 December 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Lisa R. SammaritanoAbstractAntiphospholipid syndrome is an autoimmune systemic disorder characterized by arterial, venous, or small vessel thrombosis and/or recurrent early pregnancy loss, fetal loss, or pregnancy morbidity in the setting of documented persistent antiphospholipid antibodies that include the lupus anticoagulant, or moderate-high titer anticardiolipin, or anti-β2Glycoprotein I antibodies. Associated clinical manifestations include livedo reticularis, cutaneous ulcerations, thrombocytopenia, he...
Source: Best Practice and Research Clinical Rheumatology - December 20, 2019 Category: Rheumatology Source Type: research

Autoantibodies in connective tissuedisease
Publication date: Available online 14 December 2019Source: Best Practice & Research Clinical RheumatologyAuthor(s): Ben Mulhearn, Sarah L. Tansley, Neil J. McHughAbstractAutoimmune connective tissue diseases are heterogeneous rheumatic diseases with the potential to affect multiple body systems. Autoantibodies are a characteristic feature of these diseases and are typically highly disease specific. In addition to aiding diagnosis, many autoantibodies have established associations with clinically important disease complications including internal organ involvement. In this chapter, we review the autoantibodies relevant to a...
Source: Best Practice and Research Clinical Rheumatology - December 15, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: August 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 4Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - December 4, 2019 Category: Rheumatology Source Type: research

How to investigate: Very early inflammatory rheumatic diseases
Publication date: August 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 4Author(s): Luís Sousa Inês, László Czirják, Anisur Rahman (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - December 4, 2019 Category: Rheumatology Source Type: research

Index
Publication date: August 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 4Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - December 4, 2019 Category: Rheumatology Source Type: research

Pain without inflammation in rheumatic diseases
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): Jon LampaAbstractChronic pain is a common symptom in rheumatic diseases, and the patient with pain and no signs of inflammation poses a challenge to the physician.Notably, all rheumatic diseases have components of non-inflammatory pain and a higher prevalence of fibromyalgia compared to the overall population.Hypothetically, a chronic pain stimulus may have stronger impact in a chronic inflammatory state, and the process towards a pain condition may be influenced by individual predisposition for development of ch...
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research

Index
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research

Editorial Board
Publication date: June 2019Source: Best Practice & Research Clinical Rheumatology, Volume 33, Issue 3Author(s): (Source: Best Practice and Research Clinical Rheumatology)
Source: Best Practice and Research Clinical Rheumatology - November 7, 2019 Category: Rheumatology Source Type: research