Promising clinical practices of metformin in women with PCOS and early-stage endometrial cancer
Publication date: December 2014 Source:BBA Clinical, Volume 2 Author(s): Ruijin Shao , Xin Li , Håkan Billig Young women with polycystic ovary syndrome (PCOS) have a high risk of developing endometrial cancer (EC). There is an urgent need for non-surgical prevention and treatment strategies for these patients who fail to respond to progesterone treatment and wish to preserve their fertility. Recently, we have reported that the combined treatment with metformin and progesterone-based oral contraceptives has successfully reversed the early-stage EC into normal endometria in addition to improvement of insulin resistan...
Source: BBA Clinical - November 1, 2014 Category: Biochemistry Source Type: research
