Asian Journal of Pharmaceutical Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Determination of N-trans-feruloyltyramine content and nitric oxide inhibitory and antioxidant activities of Tinospora crispa
Publication date: Available online 25 November 2015Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Attawadee SaeYoon, Bhudsaban Sukkarn, Wichit Nosoongnoen, Chutima Jantarat, Poonsit Hiransai, Pajaree Sakdiset, Jiraporn Chingunpitak, Sunita Makchuchit, Arunporn Itharat (Source: Asian Journal of Pharmaceutical Sciences)
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Factors affecting formation of microemulsions containing modified coconut oil
Publication date: Available online 25 November 2015Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Sirikarn Pengon, Chutima Limmatvapirat, Sontaya Limmatvapirat (Source: Asian Journal of Pharmaceutical Sciences)
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Preparation and optimization of fenofibrate loaded self-microemulsifying drug delivery system (SMEDDS) by application of box-behnken design
Publication date: Available online 25 November 2015Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Jin Wook Tak, Bijay Kumar Poudel, Pathak Shiva, Toe Kyung Go, Kyu bong Woo, Dong Shik Kim, Han-Gon Choi, Jee-Heon Jeong, Chul Soon Yong, Jong Oh Kim (Source: Asian Journal of Pharmaceutical Sciences)
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Optimization of trans-resveratrol extraction from peanut kernels using supercritical fluid extraction
Publication date: Available online 25 November 2015Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Kritamorn Jitrangsri, Amornrut Chaidedgumjorn, Malai Satiraphan (Source: Asian Journal of Pharmaceutical Sciences)
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design
Publication date: Available online 13 October 2017Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Thuy Tran, Thomas Rades, Anette MüllertzAbstractThe development of self-nanoemulsifying drug delivery systems (SNEDDS) to enhance the oral bioavailability of lipophilic drugs is usually based on traditional one-factor-at-a-time approaches. These approaches may be inadequate to analyse the effect of each excipient and their potential interactions on the emulsion droplet size formed when dispersing the SNEDDS in an aqueous environment. The current study investigates the emulsion droplet sizes formed from SNEDDS conta...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Development and bioequivalence study of potassium chloride extended release tablets
Publication date: Available online 23 October 2017Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Thu Van Le Thi, Nghiem Le Quan, Hau LeAbstractThe purposes of this study are to prepare the generic extended release tablet of potassium chloride (PC) 600 mg and to compare the absorption of potassium ion from the experimental tablets to that of Kaleorid® LP 600 mg (Leo Pharmaceutical Products, Denmark). Carnauba wax was used as retardant in the matrix core tablets. The core tablets were coated with blends of ethyl cellulose (EC) and hydroxypropyl methyl cellulose (HPMC) to modulate the drug release. Results of...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Challenges and trends in apomorphine drug delivery systems for the treatment of parkinson's disease
Publication date: Available online 6 December 2017Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Nrupa Borkar, Huiling Mu, René HolmAbstractParkinson's disease (PD) is a chronic debilitating disease affecting approximately 1 % of the population over the age of 60. The severity of PD is correlated to the degree of dopaminergic neuronal loss. Apomorphine has a similar chemical structure as the neurotransmitter dopamine and has been used for the treatment of advanced PD patients. In PD patients, apomorphine is normally administered subcutaneously with frequent injections because of the compound's extensive hepati...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Enhanced transdermal delivery of meloxicam by nanocrystals: Preparation, in vitro and in vivo evaluation
In conclusion, nanocrystal is advantageous for transdermal delivery of MLX.Graphical AbstractMeloxicam nanocrystals were successfully prepared by the nanoprecipitation technique based on acid-base neutralization. Nanocrystals significantly increased both in vitro and in vivo transdermal permeation of meloxicam due to increased transdermal concentration gradient and facilitated follicular permeation. (Source: Asian Journal of Pharmaceutical Sciences)
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

3D TECA hydrogel reduces cellular senescence and enhances fibroblasts migration in wound healing
This study was designed to investigate the effect of 3D TECA hydrogel on the inflammatory-induced senescence marker, and to assess the influence of the gel on the periodontal ligament fibroblasts (PDLFs) migration in wound healing in vitro. PDLFs were cultured with 20 ng/ml TNF-α to induce inflammation in the presence and absence of 50 µM 3D TECA gel for 14 d. The gel effect on the senescence maker secretory associated-β-galactosidase (SA-β-gal) activity was measured by a histochemical staining. Chromatin condensation and DNA synthesis of the cells were assessed by 4′,6-diamidino-2-phenylindole and 5-ethynyl-2′...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Design and characterization of monolaurin loaded electrospun shellac nanofibers with antimicrobial activity
Publication date: Available online 27 December 2017Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Nawinda Chinatangkul, Chutima Limmatvapirat, Jurairat Nunthanid, Manee Luangtana-Anan, Pornsak Sriamornsak, Sontaya LimmatvapiratAbstractThe aim of this study was to elucidate the optimized fabrication factors influencing the formation and properties of shellac (SHL) nanofibers loaded with an antimicrobial monolaurin (ML). The main and interaction effects of formulation and process parameters including SHL content (35%–40% w/w), ML content (1%–3% w/w), applied voltage (9–27 kV) and flow rate (0.4–1.2 ml...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Formulation and evaluation of gels containing coconut kernel extract for topical application
Publication date: Available online 31 January 2018Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Wantanwa Krongrawa, Sontaya Limmatvapirat, Nushjira Pongnimitprasert, Paranee Meetam, Chutima LimmatvapiratAbstractThe biological activity of coconut (Cocos nucifera L.) extracts from its kernels and various parts was reported by many previous studies, it is therefore believable that the extracts of its kernels might show some activities in topical formulations. Among several kernel extracts, the TC06 extract prepared by soaking the steamed coconut kernels in hot water showed the highest total phenolic content (6.98...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Design and characterization of clindamycin-loaded nanofiber patches composed of polyvinyl alcohol and tamarind seed gum and fabricated by electrohydrodynamic atomization
In this study, we developed a polymeric nanofiber patch (PNP) for topical disease treatment using electrohydrodynamic atomization (EHDA). The nanofibers were prepared using various concentrations of polyvinyl alcohol (PVA) and tamarind seed gum and loaded with clindamycin HCl as a model drug. The precursor polymer solutions were sprayed using the EHDA technique; the EHDA processing parameters were optimized to obtain blank and drug-loaded PNPs. The skin adherence, translucence, and ventilation properties of the prepared PNPs indicated that they are appropriate for topical application. The conductivity of the polymer soluti...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Predicting oral disintegrating tablet formulations by neural network techniques
Publication date: Available online 2 February 2018Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Run Han, Yilong Yang, Xiaoshan Li, Defang OuyangAbstractOral disintegrating tablets (ODTs) are a novel dosage form that can  be dissolved on the tongue within 3 min or less especially for geriatric and pediatric patients. Current ODT formulation studies usually rely on the personal experience of pharmaceutical experts and trial-and-error in the laboratory, which is inefficient and time-consuming. The aim of current research was to establish the prediction model of ODT formulations with direct compression process...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
Publication date: Available online 21 February 2018Source: Asian Journal of Pharmaceutical SciencesAuthor(s): Anna Slita, Anna Egorova, Eudald Casals, Anton Kiselev, Jessica M. RosenholmAbstractGene therapy using siRNA molecules is nowadays considered as a promising approach. For successful therapy, development of a stable and reliable vector for siRNA is crucial. Non-viral and non-organic vectors like mesoporous silica nanoparticles (MSN) are associated with lack of most viral vector drawbacks, such as toxicity, immunogenicity, but also generally a low nucleic acid carrying capacity. To overcome this hurdle, we here modif...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Quantification and spatial distribution of salicylic acid in film tablets using FT-Raman mapping with multivariate curve resolution
In this study, we proposed a rapid and sensitive method for quantification and spatial distribution of salicylic acid in film tablets using FT-Raman spectroscopy with multivariate curve resolution (MCR). For this purpose, the constituents of film tablets were identified by using FT-Raman spectroscopy, and then eight different concentrations of salicylic acid tablets were visualized by Raman mapping. MCR was applied to mapping data to expose the active pharmaceutical ingredients in the presence of other excipients by monitoring distribution maps and combination of FT-Raman mapping with MCR enabled the determination of lower...
Source: Asian Journal of Pharmaceutical Sciences - July 10, 2018 Category: Drugs & Pharmacology Source Type: research