Researchers find new signs of stress damage in the brain, plus hope for prevention
New research shows that when mice experience chronic stress, neurons within part of their brain’s fear and anxiety center, the amygdala, retract. It also suggests how such changes could be prevented. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 31, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News acetyl carnitine amygdala anxiety Bruce McEwen Bruce S. McEwen Carla Nasca depression neurosciences and behavior Stress Source Type: news

In the News – The Atlantic – Leslie Vosshall
Using CRISPR to Learn How a Body Builds Itself   “They call the technique ‘genome editing of synthetic target arrays for lineage tracing’ or GESTALT for short. ‘It’s a great starting point for understanding how a single cell gives rise … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 26, 2016 Category: Biomedical Science Authors: Jessica Rothschild Tags: In the News Source Type: news

New technique captures the activity of an entire brain in a snapshot
With a new imaging tool, scientists are able to measure the activity of all the neurons in a mouse brain with unmatched precision. The method is widely applicable for studying how the brain functions both under normal conditions and in disease. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 26, 2016 Category: Biomedical Science Authors: pubaff Tags: Science News brain mapping Laboratory of Brain Development and Repair Marc Tessier-Lavigne neuroscience and behavior Source Type: news

New method gives scientists a better look at how HIV infects and takes over its host cells
A research team wanted to know how HIV uses its tiny genome to manipulate our cells, gain entry, and replicate—all while escaping the immune system. They’ve spent a decade developing an experimental approach that finally is yielding answers. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 23, 2016 Category: Biomedical Science Authors: Wynne Perry Tags: Science News Aaron Diamond AIDS Research Center ADARC Brian Chait env HIV interactome Michael P. Rout Michael Rout vif virus virus-host interactions Source Type: news

Rockefeller tops global ranking of scientific impact
Rockefeller has the highest percentage of frequently cited scientific publications among 842 leading universities worldwide, according to a survey created by the Center for Science and Technology Studies of Leiden University. The ranking is based on publications indexed in a Thomson Reuters database between 2011 and 2014. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 19, 2016 Category: Biomedical Science Authors: Alexandra MacWade Tags: Awards and Honors CWTS Leiden Ranking Source Type: news

Scientists find evidence that cancer can arise from changes in the proteins that package DNA
Mutations in histones, the proteins that shield and package DNA, have been linked to many types of cancer, but their role in promoting disease has not been clear. Now, for the first time, scientists have found that a change to the structure of a histone can trigger a tumor on its own. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 12, 2016 Category: Biomedical Science Authors: pubaff Tags: Science News chondroblastoma David Allis epigenetics genetics and genomics histones Laboratory of Chromatin Biology and Epigenetics sarcoma Source Type: news

C. David Allis receives the 2016 Gruber Genetics Prize
Allis shares the award with Michael Grunstein of UCLA for identifying the critical role of histones and histone modification in regulating gene activity. The prize is awarded by The Gruber Foundation of Yale University and honors scientists whose work inspires fundamental shifts in knowledge and culture. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 11, 2016 Category: Biomedical Science Authors: Alexandra MacWade Tags: Awards and Honors C. David Allis epigenetics gene regulation Gruber Genetics Prize histones Laboratory of Chromatin Biology and Epigenetics The Gruber Foundation Source Type: news

Torsten Wiesel wins Karolinska Institute’s Jubilee Gold Medal
Wiesel is celebrated with the medical university’s Jubilee Gold Medal for his extraordinary contributions to the Swedish scientific community and to Karolinska itself. The Karolinska Institute, one of the world’s leading medical universities, will present Wiesel with the medal at a ceremony on May 13. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 11, 2016 Category: Biomedical Science Authors: Alexandra MacWade Tags: Awards and Honors Karolinska Institute Karolinska Institutet Karolinska Institute’s Jubilee Gold Medal Torsten N. Wiesel Torsten Wiesel Source Type: news

Antibody therapy opens door to potential new treatment for HIV
Researchers are developing an antibody-based drug that may provide a better strategy for long-term control of HIV. New results from a clinical trial suggest that a single dose of a so-called broadly neutralizing antibody enables patients’ immune systems to better fight the virus. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 6, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: Science News antibody therapy clinical trial HIV Michel C. Nussenzweig Michel Nussenzweig Rockefeller University Hospital Source Type: news

Richard P. Lifton named 11th president of The Rockefeller University
The Rockefeller University today announced that its Board of Trustees has elected Richard P. Lifton to be the 11th president of the university, effective September 1, 2016. Lifton, 62, Sterling Professor of Genetics and chair of the Department of Genetics at Yale University, will succeed Marc Tessier-Lavigne, who is leaving Rockefeller to become Stanford University’s next president. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 5, 2016 Category: Biomedical Science Authors: Zach Veilleux Tags: Campus News Source Type: news

Researchers use new CRISPR-based strategy to replicate disease in cells
With a new strategy they developed, Rockefeller scientists used the CRISPR genome editing system to engineer neurons so they looked like those in the brains of people suffering from Alzheimer’s disease. This development will aid biomedical research by making it easier to create cellular models of disease. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 4, 2016 Category: Biomedical Science Authors: pubaff Tags: Science News Alzheimer’s disease cellular models CRISPR-Cas9 Dominik Paquet Dylan Kwart genome editing Marc Tessier-Lavigne Source Type: news

A central clock runs the cell division cycle
Scientists have long known that proteins called cyclins regulate cell division in yeast, but this picture has lately come into question as oscillations in gene expression were posited to run independently in the cell division cycle. Now a new study confirms that cyclins are indeed in control. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 4, 2016 Category: Biomedical Science Authors: Eva Kiesler Tags: Science News cyclin Frederick R. Cross genomics and genetics Jamal Rahi Laboratory of Cell Cycle Genetics Source Type: news

New method allows first look at key stage of human development, embryo implantation
Almost nothing is known about the stage of human development called implantation, when the developing embryo attaches to the uterus. Now scientists have devised a method that replicates implantation in an experimental setting, providing a revolutionary system capable of answering basic questions about our own development. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 4, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: Science News Ali H. Brivanlou Amy Wilkerson bioethics developmental biology embryo development Laboratory of Stem Cell Biology and Molecular Embryology Source Type: news

In the News – Wall Street Journal – Brivanlou
Scientists Grow Embryos for Up to 13 Days Outside the Uterus   “In addition, to both teams’ surprise, the embryos outside the womb were able to ‘self-organize’ or begin to set in motion early development of key body organs without … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 4, 2016 Category: Biomedical Science Authors: Katie Fenz Tags: In the News Ali H. Brivanlou developmental biology embryo development Source Type: news

Nathaniel Heintz and Stanislas Leibler elected to the National Academy of Sciences
Heintz, who studies the inner workings of the mammalian brain, and Leibler, who explores questions related to how simple genetic and biochemical networks function, are among the new members and foreign associates to be inducted into the Academy. With Heintz and Leibler’s election, Rockefeller now boasts 37 members or foreign associates of the National Academy of Sciences among its current faculty. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - May 4, 2016 Category: Biomedical Science Authors: Alexandra MacWade Tags: Awards and Honors Laboratory of Living Matter Laboratory of Molecular Biology Nathaniel Heintz Stanislas Leibler U.S. National Academy of Sciences Source Type: news