Scientists pinpoint molecule that controls stem cell plasticity by boosting gene expression
Experiments placed Sox9 at the crux of a shift in gene expression associated with hair follicle stem cell identity. The molecule first makes stem cell genes accessible so they can become active, then recruits other molecules that promote the expression of these genes in stem cells found at the base of the hair follicle. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 19, 2015 Category: Biomedical Science Authors: pubaff Tags: Science News Elaine Fuchs hair follicle stem cells Hanseul Yang Laboratory of Mammalian Cell Biology and Development Rene Adam Sox9 stem cell plasticity super-enhancers transcription factors Source Type: news

In the News – Xconomy – Darnell
Six Takeaways From “New York’s Life Science Disruptors”   “Genomics is so daunting, it made New York institutions collaborate…The answers to so many questions are at scientists’ fingertips, but finding them is a huge undertaking. [Robert] Darnell’s lab at Rockefeller … More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 16, 2015 Category: Biomedical Science Authors: pubaff Tags: In the News Robert B. Darnell Source Type: news

New antibody therapy dramatically improves psoriasis symptoms in clinical trial
Only a single treatment produced what researchers describe as “rapid, substantial, and durable clinical improvement” in patients. This raises the prospect of a treatment that could put this autoimmune disease of the skin into long-term remission. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 13, 2015 Category: Biomedical Science Authors: pubaff Tags: Science News antibody therapy autoimmune disease interleukin-23 James Krueger Laboratory of Investigative Dermatology psoriasis Source Type: news

Lewis Thomas Prize to honor mathematicians Steven Strogatz and Ian Stewart
The first mathematicians to receive the prize for writing about science, Strogatz and Stewart will be honored at a ceremony in Caspary Auditorium on the evening of Monday, March 30. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 13, 2015 Category: Biomedical Science Authors: pubaff Tags: Awards and Honors Ian Stewart Jesse Ausubel Lewis Thomas Prize Steven Strogatz Source Type: news

Analysis of worm neurons suggests how a single stimulus can trigger different responses
In experiments, the state of a simple brain network determined the likelihood a worm would move toward a delicious smell or ignore it. Scaled up to account for the more nuanced behaviors of humans, the research may suggest ways in which our brains process competing motivations. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - March 12, 2015 Category: Biomedical Science Authors: pubaff Tags: Science News Andrew Gordus behavioral variability Cori Bargmann Laboratory of Neural Circuits and Behavior network state neuroscience Source Type: news