Canine Hypoadrenocorticism: Pathogenesis, Diagnosis, and Treatment
Hypoadrenocorticism (Addison’s disease) is an uncommon condition in dogs and even more rare in cats. Hypoadrenocorticism is most often caused by immune mediated destruction of the adrenal glands resulting in decreased mineralocorticoid and glucocorticoid production. Although less common, some dogs with hypoadrenocorticism have normal serum electrolytes. Hypoadrenocorticism causes a wide variety of clinical symptoms including gastrointestinal upset, weakness, weight loss, and hypovolemia. Laboratory and diagnostic findings vary but classic abnormalities include hyperkalemia, hyponatremia, azotemia, anemia, and lack of a s...
Source: Topics in Companion Animal Medicine - October 16, 2014 Category: Veterinary Research Authors: Kathleen Van Lanen, Allison Sande Source Type: research

Gastropexy for prevention of gastric dilatation-volvulus in dogs: History and techniques
Gastric dilatation-volvulus (GDV) is a common and catastrophic disease of large and giant breed dogs. Treatment of GDV includes medical stabilization followed by prompt surgical repositioning of the stomach in its normal anatomic position. In order to prevent reoccurrence, gastropexy is used to securely adhere the stomach to the body wall. Effective gastropexy decreases the recurrence of GDV from as high as 80% to less than 5%. The purpose of this article is to describe the history, indications and techniques for gastropexy. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Philip Allen, April Paul Source Type: research

Inherited and Predisposing Factors in the Development of Gastric Dilatation Volvulus in Dogs
This review article summarizes what is known as well as what is undetermined concerning the inherited and environmental pathogenesis of gastric dilatation volvulus in dogs. The disorder primarily affects large and giant, deep-chested breeds. A concise description of a typical dog affected with gastric dilatation volvulus is presented. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Jerold S. Bell Tags: Topical Review Source Type: research

Postoperative Management of Dogs With Gastric Dilatation and Volvulus
The objective of the study was to review the veterinary literature for evidence-based and common clinical practice supporting the postoperative management of dogs with gastric dilatation and volvulus (GDV). GDV involves rapid accumulation of gas in the stomach, gastric volvulus, increased intragastric pressure, and decreased venous return. GDV is characterized by relative hypovolemic-distributive and cardiogenic shock, during which the whole body may be subjected to inadequate tissue perfusion and ischemia. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Yaron Bruchim, Efrat Kelmer Tags: Topical Review Source Type: research

Introduction to Therapeutic Lasers in a Rehabilitation Setting
The term laser is an acronym for the light amplification of the stimulation of the emission of radiation. Interestingly, it was also referred to as the light oscillation of the stimulation of the emission of radiation - but loser is not a wonderful acronym. Laser therapy, also known as therapeutic laser, low-level laser therapy (LLT), cold laser, or just laser, is becoming more and more popular in the treatment of animals. It has also recently been pointed out as photobiomodulation and this has become a popular term for the introduction of laser. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Deborah Marie Gross Tags: Review Article Source Type: research

Plasma lactate concentration as a prognostic biomarker in dogs with Gastric Dilation and Volvulus
Gastric dilation and volvulus (GDV) is an acute condition of dogs characterized by dilation of the stomach and rotation on its mesenteric axis. Affected dogs may suffer from circulatory shock and a proportion of dogs develop gastric necrosis. Reported mortality rates for GDV vary between 10 – 33% .1–6 Biomarkers, such as plasma lactate concentration, can help guide prognostication. Understanding lactate physiology and how GDV may cause hyperlactatemia is important, but knowing how to apply the results of studies of prognostic indicators to individual animals is vital so that reasonable and proportionate prognostic info...
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Erin Mooney, Cameron Raw, Dez Hughes Source Type: research

The Relationship Between Gastrointestinal Motility and Gastric Dilatation-Volvulus in Dogs
Gastric dilatation-volvulus (GDV) is a devastating disease that most commonly affects large and giant-breed dogs. Though a number of risk factors have been associated with the development of GDV, the etiology of GDV remains unclear. Abnormal gastric motility patterns and delayed gastric emptying have been previously described in dogs following GDV. Work evaluating the effects of gastropexy procedures and changes to gastric motility after experimental GDV has not found the same changes as those found in dogs with naturally-occurring GDV. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Krista M. Gazzola, Laura L. Nelson Source Type: research

Cardiovascular and Systemic Effects of Gastric Dilatation and Volvulus in Dogs
Gastric dilatation and volvulus (GDV) is a common emergency condition in large and giant breed dogs that is associated with high morbidity and mortality. Dogs with GDV classically fulfill the criteria for the systemic inflammatory response syndrome (SIRS) and can go on to develop multiple organ dysfunction syndrome (MODS). Previously reported organ dysfunctions in dogs with GDV include cardiovascular, respiratory, gastrointestinal, coagulation and renal dysfunction. Cardiovascular manifestations of GDV include shock, cardiac arrhythmias and myocardial dysfunction. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Claire R. Sharp, Elizabeth A. Rozanski Tags: Topical Review Source Type: research

Foreword
Gastric dilatation volvulus (GDV) or in layman׳s terms “bloat” is a condition that primarily affects large- and giant-breed dogs. The last 30 years have seen tremendous advances in the preoperative stabilization of dogs with GDV, as well as surgical and postsurgical interventions. GDV has moved from a dreaded, nearly unsurvivable, condition to one with survival rates of more than 80% in treated dogs. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Elizabeth Rozanski, Claire Sharp Tags: Topical Review Source Type: research

Foreword
The science and art of rehabilitation of companion animals has undergone exponential growth over the last decade. New therapies have evolved and advanced to ease pain in our pets. More collaborative efforts between referral veterinarians, surgeons and therapists have paved the way for better pain management and faster recovery. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 18, 2014 Category: Veterinary Research Authors: Dierdre Chiaramonte Source Type: research

Table of Contents
(Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - September 1, 2014 Category: Veterinary Research Source Type: research

Adjunctive, Pain-Modifying, Analgesic Drugs
Alpha-2 and opioid receptors are co-located on central nociceptors, and use of the two drug classes together is highly synergistic for sedation and analgesia. The analgesic and sedating effect have been reported to be similar to opioids in dogs1, although used together the two drug classes are highly synergistic (allowing dose reduction of both drugs). Alpha-2 binding pre-synaptically reduces NE production and sedation occurs; binding post-synaptically, analgesia is produced. It also blocks NE receptors on blood vessels, resulting in vasoconstriction; the resulting hypertension parasympathetically induces bradycardia, whic...
Source: Topics in Companion Animal Medicine - August 1, 2014 Category: Veterinary Research Authors: Mark E. Epstein Source Type: research

Table of Contents
(Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - June 1, 2014 Category: Veterinary Research Source Type: research

WITHDRAWN: Canine Hypoadrenocorticism: Pathogenesis, Diagnosis, and Treatment
Available onlineThe Publisher regrets that this article is an accidental duplication of an article that has already been published, 10.1053/j.tcam.2014.10.001. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. (Source: Topics in Companion Animal Medicine)
Source: Topics in Companion Animal Medicine - May 15, 2014 Category: Veterinary Research Authors: Kathleen Van Lanen, Allison Sande Source Type: research