Therapeutic Advances in Cardiovascular Disease This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Early 'in-lab' use of levosimendan in patients with cardiogenic shock unsuitable for intra-aortic balloon pump counterpulsation
We report the results of four patients with ST elevation myocardial infarction, complicated by cardiogenic shock unsuitable for intra-aortic balloon pump counterpulsation treated with early levosimendan infusion during primary percutaneous coronary intervention. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - February 3, 2014 Category: Cardiology Authors: Summaria, F., Mustilli, M., Sette, A., Lanzillo, C., Romagnoli, E. Tags: Letters to the Editor Source Type: research

The key features of percutaneous coronary intervention with chronic total obstruction lesion of right coronary artery
We summarize recent research on percutaneous coronary intervention of chronic total occlusion of the right coronary artery. We then explain the method and technology of forward and backward revascularization in chronic total occlusion of the right coronary artery. Finally, we emphasize the monitoring methods and key treating measures for better prognosis of the patients. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - February 3, 2014 Category: Cardiology Authors: Lv, A., Tao, L., Cao, F., Li, Y., Guo, W., Wang, H. Tags: Review Source Type: research

Efficacy and safety of olmesartan/amlodipine/hydrochlorothiazide in patients with hypertension not at goal with mono, dual or triple drug therapy: results of the CHAMPiOn study
Conclusion: Treatment with OM/AM/HCTZ achieved superior (SBP) ABPM reductions compared with mono, dual or triple drug therapy, resulting in all patients achieving systolic ABPM goal without ABPM documented hypotension. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - February 3, 2014 Category: Cardiology Authors: Punzi, H. A. Tags: Original Research Source Type: research

Antioxidants and tumor necrosis factor alpha-inhibiting activity of sesame oil against doxorubicin-induced cardiotoxicity
Conclusion: The chronic oral administration of sesame oil prevents acute doxorubicin-induced cardiotoxicity by enhancing cardiac endogenous antioxidants and decreasing myocardial TNF-α expression. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - February 3, 2014 Category: Cardiology Authors: Saleem, M. T. S., Chetty, M. C., Kavimani, S. Tags: Original Research Source Type: research

Constrictive pericarditis in a young patient with very thick pericardium initially diagnosed as cirrhosis
Constrictive pericarditis (CP) is a disease of pericardium that restricts filling of the heart. Patients with CP generally present to hospitals with exercise-induced dyspnea, pretibial edema and abdominal ascites, and it is sometimes mistakenly diagnosed as liver or renal disease. Pericardial thickening, which is defined as more than 4 mm in diameter, is observed in nearly 80% of patients. In the present paper, we describe a case of CP with a pericardial thickness of 12 mm that was initially diagnosed as cirrhosis. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - December 10, 2013 Category: Cardiology Authors: Durmus, E., Sunbul, M., Kivrak, T., Sari, I., Mutlu, B. Tags: Letter to the Editor Source Type: research

Sevelamer revisited: pleiotropic effects on endothelial and cardiovascular risk factors in chronic kidney disease and end-stage renal disease
Endothelial dysfunction underlies multiple cardiovascular consequences of chronic kidney disease (CKD) and antecedent diabetes or hypertension. Endothelial insults in CKD or end-stage renal disease (ESRD) patients include uremic toxins, serum uric acid, hyperphosphatemia, reactive oxygen species, and advanced glycation endproducts (AGEs). Sevelamer carbonate, a calcium-free intestinally nonabsorbed polymer, is approved for hyperphosphatemic dialysis patients in the US and hyperphosphatemic stage 3–5 CKD patients in many other countries. Sevelamer has been observed investigationally to reduce absorption of AGEs, bacte...
Source: Therapeutic Advances in Cardiovascular Disease - December 10, 2013 Category: Cardiology Authors: Rastogi, A. Tags: Review Source Type: research

The relationship between serum bilirubin concentration and coronary slow flow
Conclusions: The study revealed a relationship between serum bilirubin and CSF. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - December 10, 2013 Category: Cardiology Authors: Demir, M., Demir, C., Cosar, S. Tags: Original Research Source Type: research

Comparative efficacy and adverse effects of the addition of ezetimibe to statin versus statin titration in chronic kidney disease patients
Conclusion: When statin uptitration produces adverse effects such as myopathy, combination therapy with ezetimibe is recommended instead of statin alone. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - December 10, 2013 Category: Cardiology Authors: Suzuki, H., Watanabe, Y., Kumagai, H., Shuto, H. Tags: Original Research Source Type: research

Hemodynamic and hormonal patterns of untreated essential hypertension in men and women
Conclusion: The impact of sex differences in the hemodynamic factors accounting for the elevation in arterial pressure in subjects with essential hypertension has been poorly characterized or this information is not available. We suggest that this gap in knowledge may adversely influence choices of drug treatment since our study shows for the first time significant differences in the hemodynamic and hormonal mechanisms accounting for the increased blood pressure in women compared to men. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - December 10, 2013 Category: Cardiology Authors: Ferrario, C. M., Jessup, J. A., Smith, R. D. Tags: Original Research Source Type: research

Singular and combined effects of nebivolol and lifestyle modification on large artery stiffness in hypertensive adults
Conclusion: In summary, our findings indicate that the combination of nebivolol and lifestyle modification reduced large artery stiffness to a similar degree as either intervention alone in middle-aged and older hypertensive adults. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - December 10, 2013 Category: Cardiology Authors: Werner, T. J., Boutagy, N. E., Osterberg, K. L., Rivero, J. M., Davy, K. P. Tags: Original Research Source Type: research

Sevelamer revisited: pleiotropic effects on endothelial and cardiovascular risk factors in chronic kidney disease and end-stage renal disease
Anjay RastogiDec 1, 2013; 7:322-342Review (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - November 30, 2013 Category: Cardiology Authors: Anjay Rastogi Tags: Review Source Type: research

ST-segment elevation induced by coronary artery spasm during tilt-table test
(Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - October 16, 2013 Category: Cardiology Authors: Omar, H. R., Wang, F., Fairbairn, J. Tags: Letter to the Editor Source Type: research

Left ventricular noncompaction cardiomyopathy: updated review
The first case of noncompaction was described in 1932 after an autopsy performed on a newborn infant with aortic atresia/coronary–ventricular fistula. Isolated noncompaction cardiomyopathy was first described in 1984. A review on selected/relevant medical literature was conducted using Pubmed from 1984 to 2013 and the pathogenesis, clinical features, and management are discussed. Left ventricular noncompaction (LVNC) is a relatively rare congenital condition that results from arrest of the normal compaction process of the myocardium during fetal development. LVNC shows variability in its genetic pattern, pathophysiol...
Source: Therapeutic Advances in Cardiovascular Disease - October 16, 2013 Category: Cardiology Authors: Udeoji, D. U., Philip, K. J., Morrissey, R. P., Phan, A., Schwarz, E. R. Tags: Reviews Source Type: research

Management of hypertension with fixed-dose triple-combination treatments
The objective of this review is to evaluate the role of fixed-dose triple-combination therapy for the management of hypertension. An assessment of clinical trials showed that half the patients with hypertension have uncontrolled blood pressure (BP), with underlying factors including therapeutic inertia and poor patient adherence. Many patients will require three antihypertensive agents to achieve BP goals, and current guidelines recommend combining drugs with complementary mechanisms of action. Three single-pill triple-combination treatments are available and each includes an agent affecting the renin-angiotensin-aldostero...
Source: Therapeutic Advances in Cardiovascular Disease - October 16, 2013 Category: Cardiology Authors: Epstein, B. J., Shah, N. K., Borja-Hart, N. L. Tags: Reviews Source Type: research

Echocardiographic changes and treatment goal rates after a 6-month combined treatment with amlodipine and losartan: a validation study in Andean countries (METAL study)
Conclusion: Every two of three patients of this sample of Andean countries reached adequate control after 6 months of combined antihypertensive treatment with amlodipine/losartan. (Source: Therapeutic Advances in Cardiovascular Disease)
Source: Therapeutic Advances in Cardiovascular Disease - October 16, 2013 Category: Cardiology Authors: Perez Carreno, J. G., Romero, J. D., Villar Centeno, J. C., for the METAL Study Investigators Tags: Original Research Source Type: research