A review of influenza detection and prediction through social networking sites
Early prediction of seasonal epidemics such as influenza may reduce their impact in daily lives. Nowadays, the web can be used for surveillance of diseases. Search engines and social networking sites can be us... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - February 1, 2018 Category: Biomedical Science Authors: Ali Alessa and Miad Faezipour Tags: Review Source Type: research

Time-homogeneous Markov process for HIV/AIDS progression under a combination treatment therapy: cohort study, South Africa
As HIV enters the human body, its main target is the CD4 cell which it turns into a factory that produces millions of other HIV particles. These HIV particles target new CD4 cells resulting in the progression ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - January 18, 2018 Category: Biomedical Science Authors: Claris Shoko and Delson Chikobvu Tags: Research Source Type: research

A patient-specific treatment model for Graves ’ hyperthyroidism
Graves ’ is disease an autoimmune disorder of the thyroid gland caused (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - January 9, 2018 Category: Biomedical Science Authors: Balamurugan Pandiyan, Stephen J. Merrill, Flavia Di Bari, Alessandro Antonelli and Salvatore Benvenga Tags: Research Source Type: research

On the utility of a compartmental population kinetics model of intestinal epithelial stem cell proliferation and differentiation
The small intestinal epithelium is a dynamic system with specialized cell types. The various cell populations of this tissue are continually renewed and replenished from stem cells that reside in the small int... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 19, 2017 Category: Biomedical Science Authors: Erik R. Barthel Tags: Research Source Type: research

Effects of pathogen dependency in a multi-pathogen infectious disease system including population level heterogeneity – a simulation study
Increased computational resources have made individual based models popular for modelling epidemics. They have the advantage of incorporating heterogeneous features, including realistic population structures (... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 13, 2017 Category: Biomedical Science Authors: Abhishek Bakuli, Frank Klawonn, Andr é Karch and Rafael Mikolajczyk Tags: Research Source Type: research

A mathematical model for histamine synthesis, release, and control in varicosities
Histamine (HA), a small molecule that is synthesized from the amino acid histidine, plays an important role in the immune system where it is associated with allergies, inflammation, and T-cell regulation. In t... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 12, 2017 Category: Biomedical Science Authors: Janet Best, H. F. Nijhout, Srimal Samaranayake, Parastoo Hashemi and Michael Reed Tags: Research Source Type: research

Estimating the prevalence of infectious diseases from under-reported age-dependent compulsorily notification databases
National or local laws, norms or regulations (sometimes and in some countries) require medical providers to report notifiable diseases to public health authorities. Reporting, however, is almost always incompl... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 12, 2017 Category: Biomedical Science Authors: Marcos Amaku, Marcelo Nascimento Burattini, Eleazar Chaib, Francisco Antonio Bezerra Coutinho, David Greenhalgh, Luis Fernandez Lopez and Eduardo Massad Tags: Research Source Type: research

Classification and sensitivity analysis of the transmission dynamic of hepatitis B
Hepatitis B infection caused by the hepatitis B virus is one of the most serious viral infections and a global health problem. In the transmission of hepatitis B infection, three different phases, i.e. acute i... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 5, 2017 Category: Biomedical Science Authors: Tahir Khan, Il Hyo Jung, Amir Khan and Gul Zaman Tags: Research Source Type: research

Theoretically proposed optimal frequency for ultrasound induced cartilage restoration
Matching the frequency of the driving force to that of the system ’s natural frequency of vibration results in greater amplitude response. Thus we hypothesize that applying ultrasound at the chondrocyte’s reson... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - November 14, 2017 Category: Biomedical Science Authors: April D. Miller, Anuradha Subramanian and Hendrik J. Viljoen Tags: Research Source Type: research

Anistropically varying conductivity in irreversible electroporation simulations
One recent area of cancer research is irreversible electroporation (IRE). Irreversible electroporation is a minimally invasive procedure where needle electrodes are inserted into the body to ablate tumor cells... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - November 1, 2017 Category: Biomedical Science Authors: Nicholas Labarbera and Corina Drapaca Tags: Research Source Type: research

A Theoretical Model of the Wnt Signaling Pathway in the Epithelial Mesenchymal Transition
Following the formation of a primary carcinoma, neoplastic cells metastasize by undergoing the epithelial mesenchymal transition (EMT), which is triggered by cues from inflammatory and stromal cells in the mic... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 10, 2017 Category: Biomedical Science Authors: Kelsey Gasior, Marlene Hauck, Alyson Wilson and Sudin Bhattacharya Tags: Research Source Type: research

Perspective on the dynamics of cancer
The genetic diversity of cancer and the dynamic interactions between heterogeneous tumor cells, the stroma and immune cells present daunting challenges to the development of effective cancer therapies. Althoug... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 3, 2017 Category: Biomedical Science Authors: Youcef Derbal Tags: Review Source Type: research

Forecasting infectious disease emergence subject to seasonal forcing
Despite high vaccination coverage, many childhood infections pose a growing threat to human populations. Accurate disease forecasting would be of tremendous value to public health. Forecasting disease emergenc... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - September 6, 2017 Category: Biomedical Science Authors: Paige B. Miller, Eamon B. O ’Dea, Pejman Rohani and John M. Drake Tags: Research Source Type: research

Test-and-treat approach to HIV/AIDS: a primer for mathematical modeling
The public benefit of test-and-treat has induced a need to justify goodness for the public, and mathematical modeling studies have played a key role in designing and evaluating the test-and-treat strategy for ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - September 5, 2017 Category: Biomedical Science Authors: Kyeongah Nah, Hiroshi Nishiura, Naho Tsuchiya, Xiaodan Sun, Yusuke Asai and Akifumi Imamura Tags: Review Source Type: research

Theory of synergistic effects: Hill-type response surfaces as ‘null-interaction’ models for mixtures
The classification of effects caused by mixtures of agents as synergistic, antagonistic or additive depends critically on the reference model of ‘null interaction’. Two main approaches are currently in use, th... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 2, 2017 Category: Biomedical Science Authors: Michael Schindler Tags: Research Source Type: research