Theoretical Biology and Medical Modelling This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The self-organization model reveals systematic characteristics of aging
Aging is a fundamental biological process, where key bio-markers interact with each other and synergistically regulate the aging process. Thus aging dysfunction will induce many disorders. Finding aging marker... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - March 20, 2020 Category: Biomedical Science Authors: Yin Wang, Tao Huang, Yixue Li and Xianzheng Sha Tags: Research Source Type: research

Computational modeling of the effects of autophagy on amyloid- β peptide levels
Autophagy is an evolutionarily conserved intracellular process that is used for delivering proteins and organelles to the lysosome for degradation. For decades, autophagy has been speculated to regulate amyloi... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - February 26, 2020 Category: Biomedical Science Authors: Kyungreem Han, Soon Ho Kim and MooYoung Choi Tags: Research Source Type: research

Modeling methods for estimating HIV incidence: a mathematical review
Estimating HIV incidence is crucial for monitoring the epidemiology of this infection, planning screening and intervention campaigns, and evaluating the effectiveness of control measures. However, owing to the... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - January 22, 2020 Category: Biomedical Science Authors: Xiaodan Sun, Hiroshi Nishiura and Yanni Xiao Tags: Review Source Type: research

UGM: a more stable procedure for large-scale multiple testing problems, new solutions to identify oncogene
Variations of gene expression levels play an important role in tumors. There are numerous methods to identify differentially expressed genes in high-throughput sequencing. Several algorithms endeavor to identi... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 23, 2019 Category: Biomedical Science Authors: Chengyou Liu, Leilei Zhou, Yuhe Wang, Shuchang Tian, Junlin Zhu, Hang Qin, Yong Ding and Hongbing Jiang Tags: Review Source Type: research

Modelling the effects of glucagon during glucose tolerance testing
Glucose tolerance testing is a tool used to estimate glucose effectiveness and insulin sensitivity in diabetic patients. The importance of such tests has prompted the development and utilisation of mathematica... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 12, 2019 Category: Biomedical Science Authors: Ross A. Kelly, Molly J. Fitches, Steven D. Webb, S. R. Pop and Stewart J. Chidlow Tags: Research Source Type: research

Response of membrane tension to gravity in an approximate cell model
Gravity, especially hypergravity, can affect the morphology of membranes, and further influence most biological processes. Since vesicle structures are relatively simple, the vesicle can be treated as a vital ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - December 5, 2019 Category: Biomedical Science Authors: Lili Wang, Weiyi Chen, Hongmei Guo and Airong Qian Tags: Research Source Type: research

Development and validation of a Bayesian survival model for inclusion body myositis
Associations between disease characteristics and payer-relevant outcomes can be difficult to establish for rare and progressive chronic diseases with sparse available data. We developed an exploratory bridging... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - November 7, 2019 Category: Biomedical Science Authors: Gorana Capkun, Jens Schmidt, Shubhro Ghosh, Harsh Sharma, Thomas Obadia, Ana de Vera, Valery Risson and Billy Amzal Tags: Research Source Type: research

Autophagy and apoptosis are regulated by stress on Bcl2 by AMBRA1 in the endoplasmic reticulum and mitochondria
Autophagy and apoptosis are two important physiological processes that determine cell survival or death in response to different stress signals. The regulatory mechanisms of these two processes share B-cell ly... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 29, 2019 Category: Biomedical Science Authors: Bojie Yang, Quansheng Liu and Yuanhong Bi Tags: Research Source Type: research

Evaluating the potential impact of targeted vaccination strategies against severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks in the healthcare setting
Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are two coronaviruses with demonstrated potential to generate significant nosocomial outbreaks. In particular, MERS continue... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - October 7, 2019 Category: Biomedical Science Authors: Fatima Abdirizak, Rayleen Lewis and Gerardo Chowell Tags: Research Source Type: research

The effect of group A streptococcal carrier on the epidemic model of acute rheumatic fever
Group A streptococcus (GAS) is the most frequent cause of bacterial pharyngitis in school-aged children. The postinfection sequel as acute rheumatic fever (ARF) and rheumatic heart disease that cause morbidity... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - September 10, 2019 Category: Biomedical Science Authors: Natsuda Yokchoo, Nichaphat Patanarapeelert and Klot Patanarapeelert Tags: Research Source Type: research

A quantitative method for estimating the adaptedness in a physiological study
Existed mathematical models of individual adaptation are mostly reductionist by nature. Researchers usually a priori consider the subject adapted basing only on the fact of continued or prolonged influence of ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - September 3, 2019 Category: Biomedical Science Authors: Vladimir N. Melnikov Tags: Research Source Type: research

Mathematical simulation of temperature distribution in tumor tissue and surrounding healthy tissue treated by laser combined with indocyanine green
This study is aimed to investigate the temperature distribution in tumor tissue ... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 19, 2019 Category: Biomedical Science Authors: Yuanyuan Xu, Shan Long, Yunning Yang, Feifan Zhou, Ning Dong, Kesong Yan, Bo Wang, Yachao Zeng, Nan Du, Xiaosong Li and Wei R. Chen Tags: Research Source Type: research

Steady state analysis of influx and transbilayer distribution of ergosterol in the yeast plasma membrane
The transbilayer sterol distribution between both plasma membrane (PM) leaflets has long been debated. Recent studies in mammalian cells and in yeast show that the majority of sterol resides in the inner PM le... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - August 15, 2019 Category: Biomedical Science Authors: Daniel W üstner Tags: Research Source Type: research

Effects of a high protein diet and liver disease in an in silico model of human ammonia metabolism
After proteolysis, the majority of released amino acids from dietary protein are transported to the liver for gluconeogenesis or to peripheral tissues where they are used for protein synthesis and eventually c... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - July 31, 2019 Category: Biomedical Science Authors: Jeddidiah W. D. Griffin and Patrick C. Bradshaw Tags: Research Source Type: research

The effects of time valuation in cancer optimal therapies: a study of chronic myeloid leukemia
The mathematical design of optimal therapies to fight cancer is an important research field in today ’s Biomathematics and Biomedicine given its relevance to formulate patient-specific treatments. Until now, ho... (Source: Theoretical Biology and Medical Modelling)
Source: Theoretical Biology and Medical Modelling - May 28, 2019 Category: Biomedical Science Authors: Pedro Jos é Gutiérrez-Diez, Miguel Ángel López-Marcos, Julia Martínez-Rodríguez and Jose Russo Tags: Research Source Type: research