Conditioned media from endothelial progenitor cells cultured in simulated microgravity promote angiogenesis and bone fracture healing
Paracrine signaling from endothelial progenitor cells (EPCs) is beneficial for angiogenesis and thus promotes tissue regeneration. Microgravity (MG) environment is found to facilitate the functional potentials... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 8, 2021 Category: Stem Cells Authors: Lingchi Kong, Yan Wang, Haixing Wang, Qi Pan, Rongtai Zuo, Shanshan Bai, Xiaoting Zhang, Wayne Yukwai Lee, Qinglin Kang and Gang Li Tags: Research Source Type: research
LncRNA NORAD promotes bone marrow stem cell differentiation and proliferation by targeting miR-26a-5p in steroid-induced osteonecrosis of the femoral head
Steroid-induced osteonecrosis of the femoral head (SONFH) is a devastating orthopedic disease, which seriously affects the quality of life of patients. The study aims to investigate the effects of LncRNA NORAD... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 7, 2021 Category: Stem Cells Authors: Dapeng Fu, Sheng Yang, Jianmin Lu, Haoyi Lian and Kairong Qin Tags: Research Source Type: research
Single-cell transcriptome analysis of uncultured human umbilical cord mesenchymal stem cells
Umbilical cord mesenchymal stem cells (UC-MSCs) have certain advantages over other MSCs and about 300 clinical trials have been registered using UC-MSCs to treat diseases such as osteoarthritis, autoimmune dis... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 7, 2021 Category: Stem Cells Authors: Shaoyang Zhang, Jing Yi Wang, Baojie Li, Feng Yin and Huijuan Liu Tags: Letter Source Type: research
Precision regenerative medicine
Precision or individualized medicine is increasingly pervasive across medical and surgical disciplines. However, the concept has not been introduced in regenerative medicine. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 7, 2021 Category: Stem Cells Authors: Amy L. Lightner and Timothy Chan Tags: Viewpoint Source Type: research
Improvement of the therapeutic capacity of insulin-producing cells trans-differentiated from human liver cells using engineered cell sheet
Although pancreatic islet transplantation therapy is ideal for diabetes patients, several hurdles have prevented it from becoming a standard treatment, including donor shortage and low engraftment efficacy. In... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 6, 2021 Category: Stem Cells Authors: Yu Na Lee, Hye-Jin Yi, Eun Hye Seo, Jooyun Oh, Song Lee, Sarah Ferber, Teruo Okano, In Kyong Shim and Song Cheol Kim Tags: Research Source Type: research
The potential therapy with dental tissue-derived mesenchymal stem cells in Parkinson ’s disease
Parkinson ’s disease (PD), the second most common neurodegenerative disease worldwide, is caused by the loss of dopaminergic (DAergic) neurons in the substantia nigra resulting in a series of motor or non-motor... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 6, 2021 Category: Stem Cells Authors: Zhuangzhuang Xiao, Tong Lei, Yanyan Liu, Yanjie Yang, Wangyu Bi and Hongwu Du Tags: Review Source Type: research
Characterization of traumatized muscle-derived multipotent progenitor cells from low-energy trauma
Multipotent progenitor cells have been harvested from different human tissues, including the bone marrow, adipose tissue, and umbilical cord blood. Previously, we identified a population of mesenchymal progeni... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 6, 2021 Category: Stem Cells Authors: Marvin Dingle, Stephen D. Fernicola, Jaira F. de Vasconcellos, Sonia Zicari, Christopher Daniels, John C. Dunn, Alexander Dimtchev and Leon J. Nesti Tags: Research Source Type: research
Adipose tissue-derived stem cells in breast reconstruction: a brief review on biology and translation
Recent developments in adipose-derived stromal/stem cell (ADSC) biology provide new hopes for tissue engineering and regeneration medicine. Due to their pluripotent activity, paracrine activity, and immunomodu... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 6, 2021 Category: Stem Cells Authors: Jun Fang, Feng Chen, Dong Liu, Feiying Gu and Yuezhen Wang Tags: Review Source Type: research
Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of dexamethasone
Abnormalities in apoptosis, cell cycle, proliferation, and differentiation of human bone marrow mesenchymal stem cells (hBMSCs) significantly impact bone metabolism and remodeling, resulting in various skeleta... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 6, 2021 Category: Stem Cells Authors: Tao Li, Yingxing Xu, Yingzhen Wang and Yaping Jiang Tags: Research Source Type: research
Overview of current adipose-derived stem cell (ADSCs) processing involved in therapeutic advancements: flow chart and regulation updates before and after COVID-19
Adipose-derived stem cells (ADSCs) have raised big interest in therapeutic applications in regenerative medicine and appear to fulfill the criteria for a successful cell therapy. Their low immunogenicity and t... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - January 4, 2021 Category: Stem Cells Authors: Loubna Mazini, Mohamed Ezzoubi and Gabriel Malka Tags: Review Source Type: research
Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation
An amendment to this paper has been published and can be accessed via the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - December 17, 2020 Category: Stem Cells Authors: Selami Demirci, Juan J. Haro-Mora, Alexis Leonard, Claire Drysdale, Daniela Malide, Keyvan Keyvanfar, Khaled Essawi, Raul Vizcardo, Naritaka Tamaoki, Nicholas P. Restifo, John F. Tisdale and Naoya Uchida Tags: Correction Source Type: research
Correction to: Separating mouse malignant cell line (EL4) from neonate spermatogonial stem cells utilizing microfluidic device in vitro
An amendment to this paper has been published and can be accessed via the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - December 16, 2020 Category: Stem Cells Authors: Behnaz Ashtari, Azar Shams, Narges Esmaeilzadeh, Sara Tanbakooei, Morteza Koruji, Mojtaba Johari Moghadam, Javad Mohajer Ansari, Adel Johari Moghadam and Ronak Shabani Tags: Correction Source Type: research
Quantitative assessment of the impact of cryopreservation on human bone marrow-derived mesenchymal stem cells: up to 24 h post-thaw and beyond
In this study, a quantitative approach was adopted to measure several post-thaw cell attrib... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - December 14, 2020 Category: Stem Cells Authors: Soukaina Bahsoun, Karen Coopman and Elizabeth C. Akam Tags: Research Source Type: research
ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and ERK1/2 pathways
Mesenchymal stem cells (MSCs) have exerted their brilliant potential to promote heart repair following myocardial infarction. However, low survival rate of MSCs after transplantation due to harsh conditions wi... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - December 14, 2020 Category: Stem Cells Authors: Jiaying Fu, Xuxiang Chen, Xin Liu, Daishi Xu, Huan Yang, Chaotao Zeng, Huibao Long, Changqing Zhou, Haidong Wu, Guanghui Zheng, Hao Wu, Wuming Wang and Tong Wang Tags: Research Source Type: research
Potential of resveratrol in enrichment of neural progenitor-like cell induction of human stem cells from apical papilla
Stem cell transplantation of exogenous neural progenitor cells (NPCs) derived from mesenchymal stem cells (MSCs) has emerged as a promising approach for neurodegenerative disease. Human stem cells from apical ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - December 14, 2020 Category: Stem Cells Authors: Anupong Songsaad, Thanasup Gonmanee, Nisarat Ruangsawasdi, Chareerut Phruksaniyom and Charoensri Thonabulsombat Tags: Research Source Type: research
