Pharmacological agents for improving sleep quality at high altitude: A systematic review and meta-analysis of randomized controlled trials
Several hypnotic agents commonly recommended for improving sleep at sea level are discouraged at high altitude. We aimed to evaluate the efficacy and safety of drugs prescribed for improving sleep quality in patients with acute exposure to high altitudes by conducting a systematic review and meta-analysis. An electronic search was executed for randomized controlled trials comparing drug treatments with placebo and no-treatment conditions, which used objective sleep parameters or subjective sleep quality evaluations. (Source: Sleep Medicine)
Source: Sleep Medicine - July 15, 2018 Category: Sleep Medicine Authors: Fanyi Kong, Guoyi Liu, Jingjing Xu Tags: Review Article Source Type: research
Sub-Regions of The Dorsal Raph é Nuleus Receive Different Inputs From The Brainstem
The dorsal raphe nucleus (DRN) through its extensive efferent projections has been implicated in a great variety of physiological and behavioral functions including the regulation of the sleep-wake cycle. This nucleus is composed of 5 sub-regions defined according to the distribution of its serotonergic (5-HT) neurons. In addition to its heterogeneity in neuronal populations, the DRN contains a great diversity of 5-HT neuronal subtypes identified based on their electrophysiological characteristics, morphology and sub-regional distribution. (Source: Sleep Medicine)
Source: Sleep Medicine - July 15, 2018 Category: Sleep Medicine Authors: Christelle Peyron, Claire Rampon, Jean-Marie Petit, Pierre-Herv é Luppi Source Type: research
Women with both sleep problems and snoring show objective impairment of sleep
Combined insomnia and obstructive sleep apnea has been the focus of considerable research with respect to its health effects. A related issue is whether sleep disturbances in combination with snoring might exert effects on objective sleep variables in the non-clinical general population. The purpose of the present study was to investigate the polysomnographical characteristics of individuals who had sought medical help for both disturbed sleep and for snoring. No previous work of this type has been carried out. (Source: Sleep Medicine)
Source: Sleep Medicine - July 15, 2018 Category: Sleep Medicine Authors: Torbj örn Åkerstedt, Johanna Schwarz, Georg Gruber, Jenny Theorell-Haglöw, Eva Lindberg Source Type: research
Obstructive sleep apnea and hypertension: The role of altered sleep architecture
I read with great interest the recently published article entitled “Relationship between obstructive sleep apnoea syndrome and essential hypertension: A dose−response meta-analysis” by Xia et al. [1]. The authors found that a high apnea−hypopnea index (AHI) significantly increased the risk of essential hypertension compared with a low AHI (odds ratio = 1.77 ) and reported that the risk of essential hypertension increased by 17% for every 10-events/h increase in the AHI. (Source: Sleep Medicine)
Source: Sleep Medicine - July 15, 2018 Category: Sleep Medicine Authors: Mohammad Rasoul Ghadami Source Type: research
Association of sleep disorders, chronic pain, and fatigue with survival in patients with chronic kidney disease: A meta-analysis of clinical trials
Sleep disorders, chronic pain, and fatigue have been long-standing torments in most patients with chronic kidney disease (CKD). In this review, we attempted to explore whether these nontraditional cardiovascular risk factors are associated with increased mortality in patients with CKD. (Source: Sleep Medicine)
Source: Sleep Medicine - July 15, 2018 Category: Sleep Medicine Authors: Xiu Hong Yang, Bao Long Zhang, Yan Hong Gu, Xiao Li Zhan, Li Li Guo, Hui Min Jin Tags: Review Article Source Type: research
Association between periodic limb movements during sleep and cerebral small vessel disease
Periodic limb movements (PLMs) can increase the risk of cardiovascular disease and mortality. Small vessel disease (SVD) has been considered a precursor to symptomatic stroke. We aimed to investigate the association between PLMs and cerebral SVD. (Source: Sleep Medicine)
Source: Sleep Medicine - July 12, 2018 Category: Sleep Medicine Authors: Min Kyoung Kang, Dae Lim Koo, Jung Hwan Shin, Hyung-Min Kwon, Hyunwoo Nam Tags: Original Article Source Type: research
Association of social jetlag with metabolic syndrome among Japanese working population: the Furukawa Nutrition and Health Study
Social jetlag, ie, the mismatch between biological and social timing, has been suggested to induce obesity and cardiometabolic abnormalities. Yet, no study has currently linked social jetlag to metabolic syndrome (MetS) among Asians. The aim of this study was to investigate the cross-sectional association of social jetlag with MetS in a Japanese working population. (Source: Sleep Medicine)
Source: Sleep Medicine - July 12, 2018 Category: Sleep Medicine Authors: Zobida Islam, Shamima Akter, Takeshi Kochi, Huanhuan Hu, Masafumi Eguchi, Miwa Yamaguchi, Keisuke Kuwahara, Isamu Kabe, Tetsuya Mizoue Source Type: research
Editorial Board
(Source: Sleep Medicine)
Source: Sleep Medicine - July 11, 2018 Category: Sleep Medicine Source Type: research
Longitudinal Study of Narcolepsy Symptoms in First, Second, and Third-Degree Relatives of Simplex and Multiplex Narcolepsy Families
To assess the evolution of narcolepsy symptoms in first-, second, and third-degree relatives and to compare multiplex and simplex families. (Source: Sleep Medicine)
Source: Sleep Medicine - July 6, 2018 Category: Sleep Medicine Authors: Maurice M. Ohayon, Jed Black, Andrew D. Krystal, Colin M. Shapiro, Todd J. Swick, Richard Bogan, Charles C. Wells Tags: Original Article Source Type: research
Gravitational forces, negative pressure and facial structure in the genesis of airway dysfunction during sleep: A review of the paradigm
The recent and distant literature has extensive discussion of how sleep apnea, adeno-tonsillar growth, and facial structural deformity are related. Conventionally, the order of cause and effect are: Inflammatory/infectious process →tonsillar/adenoid tissue growth→2) airway obstruction and mouth breathing/Obstructive Sleep Apnea (OSA)→3) altered facial structure (adenoid facies). Using this same reasoning, adenotonsillectomy is the first line of treatment in the prevention of structural abnormalities. (Source: Sleep Medicine)
Source: Sleep Medicine - July 6, 2018 Category: Sleep Medicine Authors: Howard D. Stupak, Steven Y. Park Tags: Review Article Source Type: research
The Unfinished Journey with Modafinil and Discovery of a Novel Population of Modafinil-Immunoreactive Neurons
Modafinil, a wake-promoting compound now used worldwide in sleep medicine, was initially regarded as a sedative compound because mice were so quiet with respect to locomotion after receiving it that this behavioral state was qualified as sedation. In the early 1980 ’s when modafinil was first assessed by polysomnography in a cat in our laboratory, surprisingly, the cat spent the whole night awake without even one minute of sleep! This initial observation resulted subsequently in a series of basic and clinical studies in order to define the pharmacological pr ofile of modafinil and its mode of action and, notably, to iden...
Source: Sleep Medicine - July 4, 2018 Category: Sleep Medicine Authors: Jian-Sheng Lin, Bernard Roussel, Alexandre Gaspar, Yan Zhao, Yiping Hou, Markus Schmidt, Anne Jouvet, Michel Jouvet Source Type: research
Sleep versus non −sleep-related fatal road accidents
To study different factors that are associated with fatal sleepiness-related motor vehicle accidents (FSMVA) and in other types of fatal motor vehicle accidents (FMVA) in Finland. (Source: Sleep Medicine)
Source: Sleep Medicine - July 4, 2018 Category: Sleep Medicine Authors: Juhani Kalsi, Timo Tervo, Adel Bachour, Markku Partinen Tags: Original Article Source Type: research
The Relationships between Improvements in Daytime Sleepiness, Fatigue and Depression and Psychomotor Vigilance Task Testing with CPAP Use in Patients with Obstructive Sleep Apnea
The purpose of this study was to determine if the subjective improvements in daytime sleepiness, fatigue and depression experienced by patients with obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) therapy predict an objective improvement in vigilance, and whether patients with mild-to-moderate OSA differ from patients with severe OSA in this regard. (Source: Sleep Medicine)
Source: Sleep Medicine - July 4, 2018 Category: Sleep Medicine Authors: Sushanth Bhat, Divya Gupta, Omar Akel, Peter G. Polos, Vincent A. DeBari, Shaista Akhtar, Anna McIntyre, Sue X. Ming, Hinesh Upadhyay, Sudhansu Chokroverty Source Type: research
Impaired cerebral oxygenation and exercise tolerance in patients with severe obstructive sleep apnea syndrome
Impaired cerebral blood flow and cerebrovascular reactivity to hypercapnia during wakefulness at rest as well as reduced exercise tolerance have been reported in severe obstructive sleep apnea (OSA) patients. Impaired cerebral oxygenation and hemodynamics can contribute to reduced exercise performance. We hypothesized that (i) OSA patients show impaired cerebrovascular response both during exercise and in response to hypercapnia together with reduced exercise tolerance and (ii) continuous positive airway pressure (CPAP) treatment improves these alterations in cerebral oxygenation. (Source: Sleep Medicine)
Source: Sleep Medicine - July 4, 2018 Category: Sleep Medicine Authors: Mathieu Marillier, Mathieu Gruet, S ébastien Baillieul, Bernard Wuyam, Renaud Tamisier, Patrick Levy, Jean-Louis Pepin, Samuel Verges Tags: Original Article Source Type: research
Sociodemographic and behavioural correlates of social jetlag in Australian adults: results from the 2016 National Sleep Health Study
This study aimed to identify the prevalence of social jetlag, and its sociodemographic and behavioural correlates, in 837 respondents who completed the Sleep Health Foundation Australia 2016 online survey. Binomial logistic regression models determined associations between social jetlag and self-reported lifestyle and work outcomes, excluding night, evening or rotating shift workers. (Source: Sleep Medicine)
Source: Sleep Medicine - July 4, 2018 Category: Sleep Medicine Authors: Carol J. Lang, Amy C. Reynolds, Sarah L. Appleton, Anne W. Taylor, Tiffany K. Gill, R. Doug McEvoy, Sally A. Ferguson, Robert A. Adams Tags: Original Article Source Type: research
