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Dosimetric impact on changes in target volumes during intensity-modulated radiotherapy for nasopharyngeal carcinoma
ConclusionTumor volume reduction during the IMRT of NPC was accompanied by deterioration of the dosimetric coverage for the different target volumes. It is essential that a careful adaptation of the treatment plan be considered during therapy for selected patients. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 18, 2019 Category: Cancer & Oncology Source Type: research

Feasibility of 4D CT Simulation with Synchronized Intravenous Contrast injection in Hepatocellular Carcinoma
ConclusionA synchronized contrast 4D CT simulation for HCC is safe and feasible. It results in good contrast enhancement comparable to a diagnostic 3D contrast CT scan. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 15, 2019 Category: Cancer & Oncology Source Type: research

Breast telecobalt beam therapy using multi-isocentric technique
ConclusionSingle isocenter technique was not feasible as the telecobalt unit did not have multileaf collimators and asymmetric jaws. With improved image based planning, a multi-isocentric technique was planned. By evaluating the dose distribution, beam modifications can be made and treatments can be given with acceptable toxicity. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 13, 2019 Category: Cancer & Oncology Source Type: research

Energy and dose dependence of GafChromic EBT3-V3 film across a wide energy range
Conclusionwithin the range 6 MV-2 mm Al HVL and dose higher than 500cGy, GafChromic EBT3-V3 films are energy independent. In this dose range, films can be calibrated in a simple geometry, using a 6 MV Linac beam, and can be used for brachytherapy sources dose measures. The use of EBT3 films can be extended to reference dosimetry in Ir-192 clinical brachytherapy. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

Cardiotoxicity of breast cancer radiotherapy – overview of current results
Publication date: Available online 9 December 2019Source: Reports of Practical Oncology & RadiotherapyAuthor(s): R. Soumarová, L. RušinováAbstractAdjuvant radiotherapy after breast cancer surgery is an important part of breast cancer treatment improving local control and overall survival. However, a higher risk of cardiac mortality was observed when conventional radiotherapy techniques were used. Cardiac morbidity and mortality after radiation therapy have been studied in many meta-analyses. In those focused on modern radiotherapy techniques, cardiac morbidity and mortality were no longer presented. However, an extremel...
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

Evaluating the predictive value of quantec rectum tolerance dose suggestions on acute rectal toxicity in prostate carcinoma patients treated with IMRT
Conclusion: Our results were not able to show any significant correlation between increasing convenience with QUANTEC limits and lower rectal toxicity. Conclusively, new dosimetric definitions are warranted to predict acute rectal toxicity more accurately in prostate cancer patients during IMRT treatment. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

Positive prostate biopsy following radiotherapy can predict metastasis-free survival in localized prostate cancer
ConclusionA positive biopsy following RT can predict MFS in localized prostate cancer. These data highlight the relevance of achieving a local control and support the use of aggressive local therapeutic interventions for PCa. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

A new strategy for craniospinal axis localization and adaptive dosimetric evaluation using cone beam CT
ConclusionOur protocol serves as a guide for precise localization of entire CSA and to ensure adequate dose to the large and complex targets. It can also be adapted for other complex treatment techniques such as total-marrow-irradiation and total-lymphoid-irradiation. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

Retrospective study on performance of constancy check device in Linac beam monitoring using Statistical Process Control
ConclusionSPC is proven to be effective for detection of loss in control in machine QA. The Ishikawa chart provides the set of probable root causes of machine error useful while troubleshooting. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

Radiobiological models in prediction of radiation cardiotoxicity
Publication date: Available online 10 December 2019Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Wiktoria M. SuchorskaAbstractCoronary disease induced by previous radiotherapy is the most common cause of death among patients treated with radiotherapy for cancer. Risk factors that may affect the frequency and intensity of radiotherapy’s cardiac toxicity are primarily the radiation dose and the volume of the heart exposed to radiation. The prolonged survival time of patients after radiotherapy, but also the intensive development of modern radiotherapy techniques results in the necessity of precise estimati...
Source: Reports of Practical Oncology and Radiotherapy - December 10, 2019 Category: Cancer & Oncology Source Type: research

Comparison of CT Artifacts and Image Recognition of Various Fiducial Markers Including Two Types of Thinner Fiducial Markers for CyberKnife Treatment
ConclusionOur results indicated that VISICOIL 0.5 × 5.0 mm and the GAs can be used nearly always for CyberKnife treatment in spite of their much thinner needles than those of cylinder types. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 9, 2019 Category: Cancer & Oncology Source Type: research

Normal tissue sparing using different techniques for prostate irradiation
ConclusionsThe dosimetric parameters for the cylindrical normal tissue volumes show that using RapidArc technique gives equal or slightly better normal tissue sparing and SIB provided the same normal tissue sparing as CFRT planned with RapidArc. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 9, 2019 Category: Cancer & Oncology Source Type: research

Change of telomerase activity in peripheral blood of patients with head and neck squamous cell carcinoma pre and post curative treatment
ConclusionIn patients with head and neck squamous cell carcinomas treated with a curative intent, the change in levels of telomerase correlates neither with the disease status nor with prognostic factors. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 1, 2019 Category: Cancer & Oncology Source Type: research

Editorial board
Publication date: November–December 2019Source: Reports of Practical Oncology & Radiotherapy, Volume 24, Issue 6Author(s): (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 27, 2019 Category: Cancer & Oncology Source Type: research

Hyperbaric oxygen therapy for radiation-induced brachial plexopathy, a case report and literature review
ConclusionsThe best management strategy of RIBP is prevention by reducing total RT doses and close follow-up. However, when RIBP occurs, we recommend treatment with HBO therapy, steroids, trental, and vitamin E as tolerable. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - November 20, 2019 Category: Cancer & Oncology Source Type: research