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Obesity in patients with carcintoma cervix increases the risk of adverse events
Publication date: Available online 26 December 2019Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Ramaiah Vinay Kumar, Suman BhaskerAbstractObesity has become epidemic both in developed and developing countries. Socio-economic (SE) development has resulted in increased prevalence of obesity across all social groups in developing countries that is contrary to the effects of a rising SE status on prevalence of obesity in the developed world. Obesity is not only associated with metabolic syndrome, cardiovascular disease, diabetes but is also a risk factor for cancer and is responsible for increased cancer mort...
Source: Reports of Practical Oncology and Radiotherapy - December 27, 2019 Category: Cancer & Oncology Source Type: research

Protection effect of cerium oxide nanoparticles against radiation-induced acute lung injuries in rats
ConclusionThe results suggested the possibility of using CNP as a future radioprotector due to its ability to protect normal cells against radiation-induced damage. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 27, 2019 Category: Cancer & Oncology Source Type: research

Dosimetric investigation of a new high dose rate 192Ir brachytherapy source, IRAsource, by Monte Carlo method
ConclusionIn line with those reported by Sarabiasl et al., the results of this study confirmed the IRAsource 192Ir source for clinical uses. The calculated dosimetric parameters of the IRAsource source could be utilized in clinical practices as input data sets or for validation of treatment planning system calculations. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 27, 2019 Category: Cancer & Oncology Source Type: research

Surface brachytherapy in the treatment of keloid scars in Mexico
ConclusionsTreatment with superficial brachytherapy in keloid scars using a mould with catheters or a Leipzig applicator is a therapeutic option that results in 95% local control and low toxicity. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 25, 2019 Category: Cancer & Oncology Source Type: research

Radiation therapy for bone-only metastases in breast cancer patients: a GOCO survey of current clinical practice
ConclusionWhile BOM breast cancer patients have a relatively good prognosis, there is a lack of consistency in their approach with RT. This can be explained by the absence of evidence-based guidelines and an incomplete availability of SBRT. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 21, 2019 Category: Cancer & Oncology Source Type: research

The importance of Image Guided Radiotherapy in small cell lung cancer: Case Report and review of literature
ConclusionsThe complete radiological response was possible due to systematic monitoring of the tumor during CRT. We recommend frequent on-site image verification. Daily CBCT should be considered with pretreatment tumor obstruction, pleural effusion, atelectasis, large volumes or radiosensitive histology that might resolve early and rapidly and could lead to a miss of the tumor or increased toxicity. Further research should be made in replanning effect in coverage of microscopic disease since it increases uncertainty in this scenario. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 21, 2019 Category: Cancer & Oncology Source Type: research

Optimization of an ultra-fast silicon detector for proton and carbon beams using GEANT4 Monte Carlo toolkit
ConclusionsThe results are reasonable, good and useful to optimize the geometry of future silicon detectors in order to be used as beam monitoring in hadron therapy applications. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 21, 2019 Category: Cancer & Oncology Source Type: research

Monte Carlo Simulation using PRIMO code as a Tool for Checking the Credibility of Commissioning and Quality Assurance of 6 MV TrueBeam STx Varian LINAC
ConclusionThe PRIMO code has good accuracy and is appropriate for use as a tool to check the credibility of beam scanning and output measurement in initial commissioning and routine QA. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 21, 2019 Category: Cancer & Oncology Source Type: research

Improvement of sensitivity of X-ray CT reading method for polymer gel in radiation therapy
ConclusionsThe sensitivity of X-ray CT reading technique of NIPAM Polymer gel depended on the slice thickness and kVp. The wiener2 filtering was useful to improving sensitivity. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 20, 2019 Category: Cancer & Oncology Source Type: research

Appropriate endpoints for stereotactic body radiotherapy for bone metastasis: classification into five treatment groups
Publication date: Available online 18 December 2019Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Kei Ito, Naoki Nakamura, Takuya Shimizuguchi, Hiroaki Ogawa, Katsuyuki KarasawaAbstractTreatment of bone metastasis using stereotactic body radiotherapy (SBRT) is being widely used in clinical practice. The reported clinical advantages of SBRT include high pain and local control rates, high response rates against bone metastasis from radio-resistant tumors, and safe re-irradiations. Although most reports in the literature use local control as the primary treatment endpoint, this endpoint is not appropriate beca...
Source: Reports of Practical Oncology and Radiotherapy - December 19, 2019 Category: Cancer & Oncology Source Type: research

Voluntary breath-hold reduces dose to organs at risk in radiotherapy of left-sided breast cancer
ConclusionThe VBH technique significantly reduces the dose to organs at risk in 3D-CRT treatment plans of left sided breast cancer. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 19, 2019 Category: Cancer & Oncology Source Type: research

Pathology of radiation induced heart disease
Publication date: Available online 17 December 2019Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Ivo ŠteinerAbstractThe aim of this paper is dual - to review the relevant literature on pathology of radiation induced heart disease (RIHD), and to present an illustrative case of our own. Therapeutic ionizing radiation, such as that used in the treatment of Hodgkin´s lymphoma and cancers of left breast, lungs, esophagus, and thymus, can cause cardiac damage that may take several years to manifest.The spectrum of RIHD is broad and includes [1] pericarditis and pericardial effusion; [2] endocardial fibrosis an...
Source: Reports of Practical Oncology and Radiotherapy - December 18, 2019 Category: Cancer & Oncology Source Type: research

Optimization of treatment planning for hypoxic tumours and re-modulation of radiation intensity in heavy-ion radiotherapy
ConclusionThe results show that taking the effect of hypoxia into account would cause the reduction of average doses delivered to the tumour tissues up to 1.54 times. In this regard, the required dose is reduced by 1.63 times in the healthy tissues before the tumour. This will result in an effective protection of healthy tissues around the tumour. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 18, 2019 Category: Cancer & Oncology Source Type: research

Single dose radiotherapy in soft tissue tumoral masses: just enough palliation
ConclusionDespite the effectiveness of SFR is well-established in BM, its use in symptoms caused by soft tissue lesions have been underreported. SFR could be a good option for providing palliation in some patients, particularly in those who are frail or have a poor performance status. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 18, 2019 Category: Cancer & Oncology Source Type: research

In vivo monitoring of total skin electron dose using optically stimulated luminescence dosimeters
ConclusionsOSLDs can be used to obtain measurements of TSET dose that can inform monitor unit adjustments and identify regions of under and over dosage, while potentially informing continuous quality improvement in TSET treatment delivery. (Source: Reports of Practical Oncology and Radiotherapy)
Source: Reports of Practical Oncology and Radiotherapy - December 18, 2019 Category: Cancer & Oncology Source Type: research