Profile of Road Traffic Accidents–related Head Injuries in Alexandria During the Egyptian Revolution 2011
Conclusions: The increased number of patients with RTA-related head injuries who were discharged from the Alexandria Main University Hospital despite medical advice, because of deficient health care resources during the Egyptian revolution 2011, necessitates the foundation of a specialized neurotrauma intensive care unit and the establishment of an efficient patients’ referral system between the governmental and private hospitals in Alexandria for better health care services, particularly for patients with moderate and severe head injuries. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - February 1, 2015 Category: Neurosurgery Tags: Original Articles Source Type: research

An Unusual Case of Extradural Primary Ewing Sarcoma of Lumbar Spine in an Adult
We present a case of an extraskeletal ES that belongs to the primitive neuroectodermal tumor/ES family occurring in the lumbar epidural space. A 46-year-old woman was admitted to neurosurgery department with the complaint of 1 month of worsening leg pain. Lumbosacral magnetic resonance imaging revealed the presence of a large, enhancing, extradural mass lesion at the level of L4 without any bony involvement. The patient underwent laminectomy and total tumor resection. ES diagnosis arising in the lumbar epidural space was confirmed by histopathologic examination. The patient received both chemotherapy and radiotherapy after...
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Report Source Type: research

The Role of Neuropsychological Evaluation in Epilepsy Surgery Candidates
Neuropsychological evaluations of preoperative epilepsy surgical candidates have been a routine portion of the multidisciplinary evaluation at most epilepsy centers for decades. Neuropsychology assessments have been explored as a means to predict and identify postoperative cognitive deficits after resections (chiefly temporal lobe), and in numerically quantifying those changes that do occur. In this manuscript, we describe the typical tools used, including tests of general intelligence, tests of language, tests of visuospatial cognition, and tests of verbal memory. Evidence for or against the use of the neuropsychological ...
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Original Article Source Type: research

Aberrant Direct Origin of the Cerebellar Arteries From the Internal Carotid Artery
The persistence of carotid-basilar anastomoses is a well known but rare condition, with the trigeminal artery being the most common. Cerebellar arteries originating directly from the internal carotid artery are considered variants of the persistent trigeminal artery and are less known. The authors present 3 cases of anomalous origin of the cerebellar arteries from the internal carotid artery and a review of the literature to elucidate their etiology and clinical implications. Although these anatomic variants are often an incidental finding, their recognition is important to explain atypical clinical presentations and for p...
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Report Source Type: research

S100B Protein Value in Predicting Brain Death After Head Trauma
Background: Protein S100B is a biomarker that reflects brain injury after trauma. In traumatic brain injury definite prediction of outcome of the patients is an important goal. In this regard, our study focuses on the S100B protein value in predicting brain death after head trauma. Methods: Seventy-two patients with a mean age of 40±17.72 years (range, 5 to 80 y; 50 male and 22 female) with severe head trauma [Glasgow Coma Scale (GCS)≤8] were recruited in this cross-sectional study. For all patients, the GCS score was evaluated, computed tomography scan was performed, and a single 5 mL blood sample was obtained from eac...
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Original Articles Source Type: research

The Role of Oxidative Stress Markers in the Pathophysiology of Migraine and After Treatment
Conclusions: The effect of oxidative stress in the pathophysiology of migraine is more likely to be an oxidant. These parameters alone are not sufficient to explain the pathophysiology of migraine because no significant changes were observed in either of antioxidant and oxidant levels, whereas a significant improvement in pain was achieved after the treatment of patients. Therefore, these results suggest that there are more than one mechanism in the pathophysiology of migraine. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Original Articles Source Type: research

Effect of Progesterone Administration on Prognosis of Patients With Diffuse Axonal Injury Due to Severe Head Trauma
Conclusions: The present study indicated that the use of progesterone may significantly improve neurologic outcome of patients suffering severe TBI up to 3 months after injury, especially those with 5≤GCS≤8, providing a potential benefit to the treatment of acute severe TBI patients. As there is no significant side effect of this drug, progesterone could be used in patients with severe TBI as a neuroprotective drug. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Original Articles Source Type: research

Ruptured Aneurysm of the Superior Cerebellar Artery Associated With Cerebellar Hemangioblastoma: A Case Report and Review of Literature
Aneurysms associated with hemangioblastoma are very rare. We encountered a patient in whom an aneurysm of the distal superior cerebellar artery, the main feeding vessel of cerebellar hemangioblastoma, ruptured and caused hemorrhage. On the basis of the computed tomography findings, the superior cerebellar artery aneurysm was identified as the source of hemorrhage, and embolization using a Guglielmi detachable coil was performed in subsequent endovascular surgery. Endovascular embolization was applied to the artery feeding the tumor at 4 weeks after admission, and the tumor was removed using an occipital transtentorial appr...
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Report Source Type: research

Middle Fossa and Sylvian Fissure Arachnoid Cysts Associated With Intracystic Hemorrhage and Subdural Hematoma
Conclusions: The annual hemorrhage risk for patients with middle cranial fossa cysts remains very low. However, when hemorrhage occurs, in most occasions it can be effectively managed only by hematoma evacuation; however, occasionally microsurgical and endoscopic cyst-wall fenestration to basal cisterns and, rarely, cystoperitoneal shunt might be needed. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Original Article Source Type: research

Cortical Dysplasia in a DNET Case Presenting With Seizures
Conclusion: To the best of our knowledge, DNET is a rare, benign intracranial neoplasm. With early and complete excision, we can get a better control of seizures, avoiding neuropsychological changes. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Report Source Type: research

Endoscopic Third Ventriculostomy in Patients With Vestibular Schwannoma and Hydrocephalus: A Clinical Trial
Conclusions: ETV is a safe procedure and an effective treatment option for hydrocephalus. Age and the analysis of underlying causes of hydrocephalus play important roles in the outcome prediction in patients with hydrocephalus who undergo ETV. Randomized clinical studies are needed to explore further the role of this treatment in patients having obstructive hydrocephalus associated with VS. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Original Article Source Type: research

Malignant Behavior of a Craniopharyngioma: A Case Report and Open Questions
We report a case of a 58-year-old man who presented with a 4-month history of visual disturbances, amnesia, and confusion. Brain magnetic resonance imaging (MRI) showed a large intrasellar and suprasellar lesion with solid and cystic components. The tumor was partially removed through a right pterional craniotomy; postoperative MRI revealed residual tumor in the interpeduncolar fossa. Histopathologic examination showed adamantinomatous craniopharyngioma. At 1 month after discharge, the patient experienced amnesia and disorientation. A new MRI showed an extraordinary increase of the residual suprasellar component. A second ...
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Reports Source Type: research

High-failure Rate of ETV in Pineal Region Glioblastoma
We present a case of pineal region glioblastoma multiforme that initially failed ETV and required subsequent shunting. In a review of the literature, this seems to be a characteristic of previously reported cases. Although ETV is commonly used to treat hydrocephalus related to a variety of pineal region tumors and is usually a very successful strategy, treating physicians should be aware that in the case of a pineal region glioblastoma multiforme there is a high failure rate of ETV and these cases are better managed by a ventriculoperitoneal shunt. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Reports Source Type: research

Congenital Glioblastoma Multiforme: A Case Report and Literature Review
Conclusions: Favorable prognosis in cGBM should be considered in a cystic solid brain lesion, the combination of gross total resection and adjuvant high dose of chemotherapy, and the absence of p53 overexpression. However, additional reports with ample number of patients are needed to strengthen our findings. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Reports Source Type: research

An Unusual Presentation of Hangman’s Fracture During Wrestling
We present the case of a 26-year-old man who sustained an Effendi Type II of hangman’s fracture with an unusual mechanism of injury that occurred while wrestling. Fractures can be treated by external immobilization or surgical intervention. (Source: Neurosurgery Quarterly)
Source: Neurosurgery Quarterly - October 30, 2014 Category: Neurosurgery Tags: Case Reports Source Type: research